ID   Q4PGV0_USTMA            Unreviewed;       849 AA.
AC   Q4PGV0;
DT   19-JUL-2005, integrated into UniProtKB/TrEMBL.
DT   19-JUL-2005, sequence version 1.
DT   01-MAY-2013, entry version 64.
DE   RecName: Full=E3 ubiquitin-protein ligase;
DE            EC=6.3.2.-;
GN   ORFNames=UM00663.1;
OS   Ustilago maydis (strain 521 / FGSC 9021) (Corn smut fungus).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC   Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Ustilago.
OX   NCBI_TaxID=237631;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=521 / FGSC 9021;
RX   PubMed=17080091; DOI=10.1038/nature05248;
RA   Kaemper J., Kahmann R., Boelker M., Ma L.-J., Brefort T.,
RA   Saville B.J., Banuett F., Kronstad J.W., Gold S.E., Mueller O.,
RA   Perlin M.H., Woesten H.A.B., de Vries R., Ruiz-Herrera J.,
RA   Reynaga-Pena C.G., Snetselaar K., McCann M., Perez-Martin J.,
RA   Feldbruegge M., Basse C.W., Steinberg G., Ibeas J.I., Holloman W.,
RA   Guzman P., Farman M.L., Stajich J.E., Sentandreu R.,
RA   Gonzalez-Prieto J.M., Kennell J.C., Molina L., Schirawski J.,
RA   Mendoza-Mendoza A., Greilinger D., Muench K., Roessel N., Scherer M.,
RA   Vranes M., Ladendorf O., Vincon V., Fuchs U., Sandrock B., Meng S.,
RA   Ho E.C.H., Cahill M.J., Boyce K.J., Klose J., Klosterman S.J.,
RA   Deelstra H.J., Ortiz-Castellanos L., Li W., Sanchez-Alonso P.,
RA   Schreier P.H., Haeuser-Hahn I., Vaupel M., Koopmann E., Friedrich G.,
RA   Voss H., Schlueter T., Margolis J., Platt D., Swimmer C., Gnirke A.,
RA   Chen F., Vysotskaia V., Mannhaupt G., Gueldener U.,
RA   Muensterkoetter M., Haase D., Oesterheld M., Mewes H.-W.,
RA   Mauceli E.W., DeCaprio D., Wade C.M., Butler J., Young S.K.,
RA   Jaffe D.B., Calvo S.E., Nusbaum C., Galagan J.E., Birren B.W.;
RT   "Insights from the genome of the biotrophic fungal plant pathogen
RT   Ustilago maydis.";
RL   Nature 444:97-101(2006).
CC   -!- PATHWAY: Protein modification; protein ubiquitination.
CC   -!- SIMILARITY: Contains 1 C2 domain.
CC   -!- SIMILARITY: Contains 1 HECT (E6AP-type E3 ubiquitin-protein
CC       ligase) domain.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data.
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DR   EMBL; AACP01000016; EAK80831.1; -; Genomic_DNA.
DR   RefSeq; XP_756810.1; XM_751717.1.
DR   ProteinModelPortal; Q4PGV0; -.
DR   SMR; Q4PGV0; 266-297, 371-401, 427-463, 470-841.
DR   STRING; 5270.UM00663.1; -.
DR   EnsemblFungi; UM00663T0; UM00663P0; UM00663.
DR   GeneID; 3628705; -.
DR   KEGG; uma:UM00663.1; -.
DR   eggNOG; COG5021; -.
DR   KO; K10591; -.
DR   OMA; NIFEDAY; -.
DR   OrthoDB; EOG4SXRMK; -.
DR   UniPathway; UPA00143; -.
DR   GO; GO:0005622; C:intracellular; IEA:InterPro.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
DR   InterPro; IPR000008; C2_Ca-dep.
DR   InterPro; IPR008973; C2_Ca/lipid-bd_dom_CaLB.
DR   InterPro; IPR018029; C2_membr_targeting.
DR   InterPro; IPR024928; E3_ub_ligase_SMURF1.
DR   InterPro; IPR000569; HECT.
DR   InterPro; IPR001202; WW_dom.
DR   Pfam; PF00168; C2; 1.
DR   Pfam; PF00632; HECT; 1.
DR   Pfam; PF00397; WW; 3.
DR   PIRSF; PIRSF001569; E3_ub_ligase_SMURF1; 1.
DR   SMART; SM00239; C2; 1.
DR   SMART; SM00119; HECTc; 1.
DR   SMART; SM00456; WW; 3.
DR   SUPFAM; SSF49562; C2_CaLB; 1.
DR   SUPFAM; SSF56204; HECT; 1.
DR   SUPFAM; SSF51045; WW_Rsp5_WWP; 3.
DR   PROSITE; PS50004; C2; 1.
DR   PROSITE; PS50237; HECT; 1.
DR   PROSITE; PS01159; WW_DOMAIN_1; 3.
DR   PROSITE; PS50020; WW_DOMAIN_2; 3.
PE   4: Predicted;
KW   Complete proteome; Ligase; Reference proteome;
KW   Ubl conjugation pathway.
SQ   SEQUENCE   849 AA;  94114 MW;  4A4FCFB3127E461A CRC64;
     MVNPRAPGSL SRKIRITVVA ADGLAKRDVF RLPDPFAIVT VDGEQTHSTS VIKKTLNPYW
     NDSFDVNVTD SSVIAVQIFD QKKFKKRDQG FLGVINIRVA DVLDLELGGK RLLNKELKKS
     NDNLVVHGKL IIDLNTNVST PINNNSTAGP TNLLVPGTSN ASSASLATPS SSSVTRSDAP
     PNTSGSGAIA AAATAASTAS TNGDTSSRPA STIDTASSSA SVTVPSSAAT TPSAGVNNEA
     RSSAAPTSTA SRPNPSQDTR SDEYGPLPAG WERRTDHLGR TYYVDHNTRS TTWTRPSTNP
     SANDAAAASS SAADRQRHSN RALADDFLGV NDGDTSRSSA TGSTATSPGA AAASANPLPA
     SSSTTAGNGP LPAGWEQRHT PEGRPYFVDH NTRTTTWVDP RRQQILRIMG PNGSNLTVQP
     QSVSQLGPLP SGWEMRLTST ARVYFVDHNT KTTTWDDPRL PSSLDQNVPQ YKRDFRRKLI
     YFRSQPALRP IPGQCHIKVR RTHIFEDSYA EIMRQQPNDL KKRLMIKFDG EDGLDYGGLS
     REFFFLLSHE MFNPFYCLFE YSAHDNYTLQ INPHSGINPE HLNYFKFIGR VLGLAIFHRR
     FLDAYFIVSF YKMILKKKIT LSDLESVDAD YHRSLQWMLD NSIEGIVEET FTAVEDKFGE
     MVTVELKKGG EEVEVTDENK KEYVDLMTEW RISKRVEEQF KAFISGFTEL IPQDLINVFD
     ERELELLIGG MSEIDVDDWK KFTDYRGFTE QDQVVQWFWQ CVRAWPTEKK SRLLQFATGT
     SRIPVNGFKD LQGSDGPRRF TIEKSGDVNQ LPKSHTCFNR IDLPPYPSFE TLESKLALAI
     EEGMGFGNE
//