ID Q4RW15_TETNG Unreviewed; 4301 AA.
AC Q4RW15;
DT 19-JUL-2005, integrated into UniProtKB/TrEMBL.
DT 19-JUL-2005, sequence version 1.
DT 27-MAR-2024, entry version 115.
DE RecName: Full=[histone H3]-lysine(4) N-methyltransferase {ECO:0000256|ARBA:ARBA00023620};
DE EC=2.1.1.364 {ECO:0000256|ARBA:ARBA00023620};
GN ORFNames=GSTENG00028083001 {ECO:0000313|EMBL:CAG07417.1};
OS Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon
OS nigroviridis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Tetraodon.
OX NCBI_TaxID=99883 {ECO:0000313|EMBL:CAG07417.1};
RN [1] {ECO:0000313|EMBL:CAG07417.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15496914; DOI=10.1038/nature03025;
RA Jaillon O., Aury J.-M., Brunet F., Petit J.-L., Stange-Thomann N.,
RA Mauceli E., Bouneau L., Fischer C., Ozouf-Costaz C., Bernot A., Nicaud S.,
RA Jaffe D., Fisher S., Lutfalla G., Dossat C., Segurens B., Dasilva C.,
RA Salanoubat M., Levy M., Boudet N., Castellano S., Anthouard V., Jubin C.,
RA Castelli V., Katinka M., Vacherie B., Biemont C., Skalli Z., Cattolico L.,
RA Poulain J., De Berardinis V., Cruaud C., Duprat S., Brottier P.,
RA Coutanceau J.-P., Gouzy J., Parra G., Lardier G., Chapple C.,
RA McKernan K.J., McEwan P., Bosak S., Kellis M., Volff J.-N., Guigo R.,
RA Zody M.C., Mesirov J., Lindblad-Toh K., Birren B., Nusbaum C., Kahn D.,
RA Robinson-Rechavi M., Laudet V., Schachter V., Quetier F., Saurin W.,
RA Scarpelli C., Wincker P., Lander E.S., Weissenbach J., Roest Crollius H.;
RT "Genome duplication in the teleost fish Tetraodon nigroviridis reveals the
RT early vertebrate proto-karyotype.";
RL Nature 431:946-957(2004).
RN [2] {ECO:0000313|EMBL:CAG07417.1}
RP NUCLEOTIDE SEQUENCE.
RG Genoscope;
RG Whitehead Institute Centre for Genome Research;
RL Submitted (FEB-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine = H(+) +
CC N(6)-methyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine;
CC Xref=Rhea:RHEA:60264, Rhea:RHEA-COMP:15543, Rhea:RHEA-COMP:15547,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:29969, ChEBI:CHEBI:57856,
CC ChEBI:CHEBI:59789, ChEBI:CHEBI:61929; EC=2.1.1.364;
CC Evidence={ECO:0000256|ARBA:ARBA00024515};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:60265;
CC Evidence={ECO:0000256|ARBA:ARBA00024515};
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CAG07417.1}.
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DR EMBL; CAAE01014991; CAG07417.1; -; Genomic_DNA.
DR KEGG; tng:GSTEN00028083G001; -.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0140999; F:histone H3K4 trimethyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd15698; ePHD2_KMT2D; 1.
DR CDD; cd22027; HMG-box_KMT2D; 1.
DR CDD; cd15597; PHD3_KMT2D; 1.
DR CDD; cd15513; PHD5_KMT2C_like; 1.
DR CDD; cd15601; PHD5_KMT2D; 1.
DR CDD; cd19171; SET_KMT2C_2D; 1.
DR Gene3D; 3.30.160.360; -; 1.
DR Gene3D; 1.10.30.10; High mobility group box domain; 1.
DR Gene3D; 2.170.270.10; SET domain; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 4.
DR InterPro; IPR034732; EPHD.
DR InterPro; IPR003889; FYrich_C.
DR InterPro; IPR003888; FYrich_N.
DR InterPro; IPR009071; HMG_box_dom.
DR InterPro; IPR036910; HMG_box_dom_sf.
DR InterPro; IPR041964; KMT2D_ePHD2.
DR InterPro; IPR047000; KMT2D_PHD3.
DR InterPro; IPR046999; KMT2D_PHD5.
DR InterPro; IPR003616; Post-SET_dom.
DR InterPro; IPR001214; SET_dom.
DR InterPro; IPR046341; SET_dom_sf.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR45888:SF2; HISTONE-LYSINE N-METHYLTRANSFERASE 2D; 1.
DR PANTHER; PTHR45888; HL01030P-RELATED; 1.
DR Pfam; PF05965; FYRC; 1.
DR Pfam; PF05964; FYRN; 1.
DR Pfam; PF00628; PHD; 2.
DR Pfam; PF00856; SET; 1.
DR SMART; SM00542; FYRC; 1.
DR SMART; SM00541; FYRN; 1.
DR SMART; SM00398; HMG; 1.
DR SMART; SM00249; PHD; 4.
DR SMART; SM00508; PostSET; 1.
DR SMART; SM00317; SET; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 3.
DR SUPFAM; SSF82199; SET domain; 1.
DR PROSITE; PS51805; EPHD; 1.
DR PROSITE; PS51543; FYRC; 1.
DR PROSITE; PS51542; FYRN; 1.
DR PROSITE; PS50868; POST_SET; 1.
DR PROSITE; PS50280; SET; 1.
DR PROSITE; PS50016; ZF_PHD_2; 3.
PE 4: Predicted;
KW Chromatin regulator {ECO:0000256|ARBA:ARBA00022853};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT DOMAIN 186..239
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 236..286
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 313..368
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 3793..3901
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS51805"
FT DOMAIN 4161..4277
FT /note="SET"
FT /evidence="ECO:0000259|PROSITE:PS50280"
FT DOMAIN 4285..4301
FT /note="Post-SET"
FT /evidence="ECO:0000259|PROSITE:PS50868"
FT REGION 38..135
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 635..657
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 722..763
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 839..1105
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1244..1286
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1316..1347
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1591..1718
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1835..1893
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1944..1990
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2106..2137
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2236..2262
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2274..2293
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2480..2500
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2564..2651
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2671..2697
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2709..2839
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2959..3074
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3110..3135
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3196..3223
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3289..3309
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3392..3413
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3510..3542
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3601..3739
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 2512..2546
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 86..100
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 873..894
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 944..958
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 990..1020
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1054..1076
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1086..1100
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1255..1269
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1327..1347
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1591..1609
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1616..1659
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1681..1697
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1835..1856
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1957..1983
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2121..2136
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2236..2251
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2564..2606
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2634..2651
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2671..2695
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2709..2814
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3017..3053
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3113..3135
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3605..3623
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3631..3649
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3703..3722
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3723..3739
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:CAG07417.1"
SQ SEQUENCE 4301 AA; 468594 MW; 53AD8EE674656CA8 CRC64;
EEEEEDDDPL REEPCVVIKQ ELQEQKIKPV LLLDETSNLS HGDESSSGFL GSPGEPDSHL
SMEFGLESGA HSHADNLLTE TDDSLPFEPL RSDREKVKRR GSPGRSRIKQ GRSSGFPGRR
RPRGGGGGRG RGGRSRLKAM ASCIDAVLLS MASDTGVTKE EEEEEDDTMQ NTVVLFSNTD
KFVLLQDMCV VCGSFGKGSE GQLLACAQCA QCYHPYCVNS KITKTKLRKG WRCLECIVCE
MCGKASDPSR LLLCDDCDVS YHTYCLEPPL HNVPKGGWKC KWCVCCVQCG SNTPGFHCEW
QNNYTHCGPC ASLVTCPVCR ENFMEEELLL QCQYCDRWVH AVCESLYTED EVEQASDEGF
ACTYCAPYVP KPVAIMASIK IKEPEPQFYR LEGVWLTESG MSLLRSISMS PLHKRRQRRS
RLGTLCCDGG ADGMDLREVE GDGEEGKGNK LQGHLDGGVE KDACVEGAEG MADCDLLKGG
EDTEDSKKRK RKPYRPGWLL FYSERTNFLR YPSSHKMFTD NLFLNGVRNR RLHAFSHSSQ
HLHSCLNAFL QEAFFGKTLI DLCKRAVLIP PGQRPASCLV RPSLPAQAGL KIPSPGCESM
SLFIFVDLIE TALKPKIVLF FKGVSASFLS LKNPATTDPH DSDAEKNEGL PQGVESQDSE
QFFRKVLGVS DGSSLGSMKP IIESGKGESH TALPQRALLP GSLPSAEMVD AFPGLSQSPF
LDMRERGGLF SPDGGEESPW ATPSTPVTPS SPSTPNETEG DGLSYNQRSL QRWEKDEELG
ELSTISPVLY ANTNFPTLKR DYPDWASRCK QIMKIWRKVS AADKVPYLQK AKDNRAAQRI
SKAQKQAESQ VCRPVKTETG RMKERPNLHL QIPPPSGSVS ASSQPSSAES PFPLLPDSGS
SVFFSDGPVR TPGSAEIRTD PLAKFPPQSP HCHSHPPTPF SHVGASPLQA SFSGYVPSGP
QGPPQGRPAS LGPFDMQPGT PGTPRRAQQV DPYFRSQLQK QQGHLTQSQP GSQESLAPSG
SPHSRVAGLG ESPMFSPSHS THYGDAFRNQ QGMGRPEYGS SPSHSGQTSS PANTGQYRAD
MGVPSPRSST GRTELSTGSP AGMLESGDGL FKAPMTPRMH QGGWWGRFTL ELLLAIPLKV
TNSLLPTRFL NHHLFPDHSL VTIVPLARRD IQLINKKCVQ ECPPAHSPTA TLSLPTLLEV
TPMTVTLPSL QPHLAFSPRN IVLSHPLDHS QEMRLLLSTN PLRSPSVAPE AASFKNSPHP
TNSSLGDPLS GKPSAPPHFS SIPSAGGFQV TQQQNQMLQG QLQQPQAQQN IGAENYGARV
PTPSGSQEVP AIRQPEPSHQ PTLPGTQEMS DISAVQDPAL GGLSPSELEK HRQRRKLQTA
AAAAAAAAAG KASSGWSGGE ISTFQQDKTH RAPPPYPQDR VSMSAAGAQA PVAGKMPVGG
FEDKLIRPPP MGTPAIMDPN TLRPQGPPRP QGMFSRPPFP PHWQDQAAGP RRFPQPDLQA
MGIRHNLNPA ANVQNMDGLG NPHAIITGHG GETMQPMSQG PPPQFIELRH NSQRLPLRPQ
FMPRGPQPRT RLFVPQQTMS APYVPQHPVA QAGSIQTDGG TNSQMGLHQG GLSVLLPQQP
PGSVTHKTHM GPQAASSTPN MSNVQSQLPP QSVVTRPHPA TVENSEELPE PDLEGLGDTS
ADGGVEDEDD LALDLDPDKG DDDLGNLDNL ETNDPHLDDL LNSDEFDLLA YTDPELDQGD
PKDVFSDQLR LVEAETEAPS SGTVSVKVEV KMEQGQKSTT VHSTACTSAN QLPASSSTAQ
NLKIKVEDSG LIPPGQPRQI VKDEIGEAVS ALLGATTPSP KSAQSENHSA SLSSVRLGGL
SYPLPTQTDP LHFPPTGSDA DDDPLELPDV GGQHSPAVDL AKVESSLDGE LPLLIQDLLE
HEKKEQQKQQ QLNSLHQGSV AAHFPSISNQ QPNPQVPGQI MLPPHHRPPP QGMMGPPGMV
PRPPHMQQQQ QQQQRLMGAG LVPPPHMAMN QQQTMIRMGQ PGIHAGLGHQ QQLQSGVKQP
PLSNNFFPDK DLDKFATDDI MDPIAKAKMV ALKGINRVLA QDPMVVPPGI NREQVSLLAQ
RLASAPATDA GQLASGPPKE GEPSDSTQSR PNPPQFVQGI INDAEKHQYE EWLLHTQQLL
QMQLKFLEEQ IGVHRKSRKA LCAKQRTAKK AGREFAEADA EKLKLVTEEQ SKIQKQLDQV
RKQQKEHTNL IAEYRSKQQQ HQQSSGLLNP GHSGQAGGPH MFPKMPGQMA IGQQGGQVMG
QQGGQVMGQQ GGQVMGQHPT MMPQGGMPVR MPQGQPFVGG PQPQLPGTLG NSSVRGPGPA
GTPARFFAQG PGMQGPDARL LQERQLQHRM QMAKLQQQQQ QMMMGQQPMP HTGNSQATMI
PQTQPGMIGN PVMAQQQVNA PQAMLTNQAS QQGMMQVPLP QNLAGQPIHH AQAMAAQPGI
MGNQQVALSE QQRPMQMLSQ QGMVGSPGHP GIRGPHSNLT PQQQNILAQR MLASQQQQQQ
QQQQQQLQLQ QQQQQQQQQL QLQQQQSVEK NMIQFQQQQQ LAQKQQPMQV SSQPSQEQGG
LSQPSTPQMG SSPCAGSVTP QPHGGTDGQN PCLKESGLLS PESKTPPQHS GPPTPSQAHQ
VASANQLQQN QIQDHSNLQK QTGLVGNQQQ SVVLQQQQQP PLLPLQRQGS ITDDKPNLMN
IKEEGKAIDV SAQQQQPQQK AVQNPMMQTQ DSSMQLQGLG QPHPGQQQPV GIGGSPQQQA
LMAQQRQQAM MGALRAQQQG ITAQRPTPST RTDPRPCQHP GYNSSESSAP QPSPQPADTA
HPGHNRPEAA PAGTDAAYVH GPRSNKVSYA CRTSVTGWTA APAQRVASWH SFSNAAGDDG
FRATAATRRR DDAKYLKKSG TGTRLPWRDG RMAMPASPCQ PVANPPGDPQ RHTFNQNMAM
RPPTPTQNQQ ALMAAGSRMQ GSPSHAYSPR GPFGMSPVHP ASPHSSHASS LWGMGGQEGA
VHTVKSPGAK SPLDSLVLKV ETQTSGSETS QTASGIPNGP QKGFNSKQHT QQVPEGPCPH
AHHGPSGDDP GRFSLQNIKQ EPREVHCDSA ALANSKAVKR EVTGEAVASG NNAGFINEGN
MSGDPGNQGP RSETGQQLLQ KLLKTKNLQL GAQRPSDGIH NEINGHINTK LAMLEQKLQG
TPQNMEDLQS ITKRAPVQKP KRTIKATGGP NARKKNKKEE VGKSAETLIK QLKQGLSLLP
LMEPSITASL DLFAPFGSSP ANDKAQLKGS FGNAVLDNIP DYYSQLLTKN NLSNPPTPPS
SLPPTPPPSV QHKMLNGVTS AEELTSGKKP AEVPMGKSGT FICMDSRLSG ILLQVRFSLT
ESVTDEVKSV DILAALPTPP HNQNEDIRME SDDEDAPESI IPASSPESNI GDEAKRFPHL
REPKEEETER AISPIIPLIP RTTIPAFPEN RLLEGSGGKV ASTSNHWQKA KSNEVSVTVT
LSSAAAKKLN HVMLAMAQLL NIQMPGSYEL SFPPQNPDTP GFDGPGKSPS QSEPLGLSES
AAVSQEEWLR QFDVSLPGCT LKKHVDILAL IKQEFSEKED RPVQHCYTTN VSDLDVRHLP
DIPVEESPPL SPSPPPPAAC APVPSSEAKP VKKSAPSSPA SSSPSLQIKT EAEGEGGAAA
DAAQTADARE SEGLEAKEAP ADSCPDPQPA APPEVHPAAT EENLTADQAQ PPEDPSNNME
SSMKALKHRR PLSPDEEEAL PNVKKWKGIR WKRLPIVISI RKGNSKKETS REVSELMESL
RITLRPEKLP RDKRKCCFCH EEGDGATDGP ARLLNIDVDL WVHLNCALWS TEVYETQGGA
LMNVEVALRR GLRTLCAFCQ KTGATNSCNR LRCPNVYHFA CAIRARCMFF KDKTMLCTQH
KLKGPSEDEL SVFAVLRRVY IERDEVKQIA SILQRGDRIH LFRVGGLIFH AVGQLLPSQM
SNFHSPTAIF PVGYEATRIY WSTRLPNKRC RYRCRISEDD GQPLFEVRVL EHGLEDLQFR
DGTPEGIWNQ VVQKVAQLRE ESSMLKLFTE HVKGEDMYGL TIHAVMRITE SLPGVENCQN
YQFRYGRHPL MELPLMINPT GCARSEPKVS TQCKRPHTLN STSVSKAYQS TFTGELNTPY
SKQFVHSKSS QYRRLKTEWK NNVYLARSRI QGLGLYAAKD LEKHTMVIEY IGTVIRNEVA
NRREKIYESQ NRGIYMFRIN NEQVIDATLT GGPARYVNHS CAPNCVAEVV TFDKEDKIII
ISSRRIPKGE ELTYDYQFDF EDDQHKIPCH CGAWNCRKWM N
//
