ID Q4WX29_ASPFU Unreviewed; 1191 AA.
AC Q4WX29;
DT 05-JUL-2005, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2005, sequence version 1.
DT 27-MAR-2024, entry version 94.
DE SubName: Full=PX domain protein {ECO:0000313|EMBL:EAL92774.1};
GN ORFNames=AFUA_3G08020 {ECO:0000313|EMBL:EAL92774.1};
OS Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 /
OS Af293) (Neosartorya fumigata).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Fumigati.
OX NCBI_TaxID=330879 {ECO:0000313|EMBL:EAL92774.1, ECO:0000313|Proteomes:UP000002530};
RN [1] {ECO:0000313|EMBL:EAL92774.1, ECO:0000313|Proteomes:UP000002530}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100
RC {ECO:0000313|Proteomes:UP000002530};
RX PubMed=16372009; DOI=10.1038/nature04332;
RA Nierman W.C., Pain A., Anderson M.J., Wortman J.R., Kim H.S., Arroyo J.,
RA Berriman M., Abe K., Archer D.B., Bermejo C., Bennett J., Bowyer P.,
RA Chen D., Collins M., Coulsen R., Davies R., Dyer P.S., Farman M.,
RA Fedorova N., Fedorova N., Feldblyum T.V., Fischer R., Fosker N., Fraser A.,
RA Garcia J.L., Garcia M.J., Goble A., Goldman G.H., Gomi K.,
RA Griffith-Jones S., Gwilliam R., Haas B., Haas H., Harris D., Horiuchi H.,
RA Huang J., Humphray S., Jimenez J., Keller N., Khouri H., Kitamoto K.,
RA Kobayashi T., Konzack S., Kulkarni R., Kumagai T., Lafon A., Latge J.P.,
RA Li W., Lord A., Lu C., Majoros W.H., May G.S., Miller B.L., Mohamoud Y.,
RA Molina M., Monod M., Mouyna I., Mulligan S., Murphy L., O'Neil S.,
RA Paulsen I., Penalva M.A., Pertea M., Price C., Pritchard B.L., Quail M.A.,
RA Rabbinowitsch E., Rawlins N., Rajandream M.A., Reichard U., Renauld H.,
RA Robson G.D., Rodriguez de Cordoba S., Rodriguez-Pena J.M., Ronning C.M.,
RA Rutter S., Salzberg S.L., Sanchez M., Sanchez-Ferrero J.C., Saunders D.,
RA Seeger K., Squares R., Squares S., Takeuchi M., Tekaia F., Turner G.,
RA Vazquez de Aldana C.R., Weidman J., White O., Woodward J., Yu J.H.,
RA Fraser C., Galagan J.E., Asai K., Machida M., Hall N., Barrell B.,
RA Denning D.W.;
RT "Genomic sequence of the pathogenic and allergenic filamentous fungus
RT Aspergillus fumigatus.";
RL Nature 438:1151-1156(2005).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAL92774.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AAHF01000002; EAL92774.1; -; Genomic_DNA.
DR RefSeq; XP_754812.1; XM_749719.1.
DR AlphaFoldDB; Q4WX29; -.
DR STRING; 330879.Q4WX29; -.
DR EnsemblFungi; EAL92774; EAL92774; AFUA_3G08020.
DR GeneID; 3512395; -.
DR KEGG; afm:AFUA_3G08020; -.
DR VEuPathDB; FungiDB:Afu3g08020; -.
DR eggNOG; KOG2273; Eukaryota.
DR HOGENOM; CLU_007739_1_1_1; -.
DR InParanoid; Q4WX29; -.
DR OMA; YGDFAKF; -.
DR OrthoDB; 1449900at2759; -.
DR Proteomes; UP000002530; Chromosome 3.
DR GO; GO:0035091; F:phosphatidylinositol binding; IBA:GO_Central.
DR CDD; cd06869; PX_UP2_fungi; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR InterPro; IPR024554; DUF3818_PX-associated.
DR InterPro; IPR024555; PX-associated.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR047168; YPR097W-like.
DR PANTHER; PTHR47185; PX DOMAIN-CONTAINING PROTEIN YPR097W; 1.
DR PANTHER; PTHR47185:SF1; PX DOMAIN-CONTAINING PROTEIN YPR097W; 1.
DR Pfam; PF12825; DUF3818; 1.
DR Pfam; PF00787; PX; 1.
DR Pfam; PF12828; PXB; 2.
DR SUPFAM; SSF64268; PX domain; 1.
DR PROSITE; PS50195; PX; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002530}.
FT DOMAIN 206..380
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
FT REGION 1..27
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 264..336
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 854..892
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 945..968
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1019..1090
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 269..303
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 314..332
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 854..868
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 869..892
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1041..1055
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1056..1083
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1191 AA; 135298 MW; F03F6E9B067BDB2E CRC64;
MLDATPASHD ADRLQSAGRP LSTHVPPGQI LTGKQEHYLK RELIGRQVRN EITELNSPTA
LHRFGAPFKS EFGEVAPVDS ELPILRYIFV HHVRKFPFLD QAREKEFWQD KLQVVSNLHQ
FGLSAVAGDS LRLTYFFMQF LESFANKHVS SSEDRLEETK RRKLARKAEK LVELMMVSGI
PTASGYEERI SFSEMEVVDR GANEKGLLVN MPEGHAIHGW DVNVAAEFIL RVQREGKPDI
FVARRYGEFA KLYRRLRTEF PGRTLAPLPR KNKSSTSTSF FGSADDEASS ISSVSTQDTS
EGYIGRTLAP GPHHSRSLSR SSMKSSKSGR LSSEGPRECV LYREEQRVSL RAFLRTLLQN
KRVSESKAME EFLTANPVTL NEEELTDVER RKAADAIRIE EQKQFYEIAR QRAAELDVYM
EQFRRDIVES NGLTKLFSEI REKNTIADLS PQYQKFAEWL RIEVAATLYH VFLAEDNSPE
MFAQFKRIHS LVPYTLLKNV IRIANPAAVM SGVLDLFLAQ PFGSRSLLQR IFSMALNDGI
KQFQKSIDSL AAKVDDPVLT GKLKEFTHAD ENIKNEIRTE AATEDVDLIV AILRSDLIAP
ELTPEQVGKV FNAYVAWNHA VDNVDLEMQE GAQWFANMKQ LLKLYTRQRD KAMILSIIEE
PVTLQLFRDL FTIFYEPLVR VYKSANVYSS ITDFAQFADD AIAVIEKCHR QDVSADPNQT
VQAFIDLCER HQDNFYKFIH EVHLHDNGLF TSLMGWIEDI LEFLRHGPQG GKLDMNALFH
GAKDVGQIDE AKAIEEINAL IKWHEDRKRW HLNKTRQKMA AEGTGNESFP GNATFRGSDF
GLDEADLEDL AISDAESEES EEMEEDDLDP ITAERRRRVK KQDQLRRTAG EPVKPEVQEI
LKLSESFNAI DTVYTCQKPQ HKRCNFFLWQ SDADAREKLT VLSNSRTEPF SANNTPTKPS
VQGSGLLTPQ TDTKVQDVRG MSVNRTPTPS KSGKARMMME DTDEFSWDDS TDAEELTKLL
EPPPQPDFGQ EGPRKAPRTE SFMSPGKRKL SDIENDGRQS TATFTPTSIF SSRTQTRLPP
ASAEVSMTPT PGRYRNVLST DARDDFSELG LQALKILESH KVVVPKQAQD ELLALLNKHD
LKMKGIMRGR DISRIALKKH EETIMKLNER ITSLESQREM DRAIIDGLRG R
//
