ID   Q54S87_DICDI            Unreviewed;       341 AA.
AC   Q54S87;
DT   24-MAY-2005, integrated into UniProtKB/TrEMBL.
DT   24-MAY-2005, sequence version 1.
DT   01-MAY-2013, entry version 51.
DE   SubName: Full=Ceramide synthase;
GN   Name=crsA; ORFNames=DDB_G0282607;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Mycetozoa; Dictyosteliida; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RG   The Dictyostelium discoideum Sequencing Consortium;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A.,
RA   Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q.,
RA   Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F.,
RA   Bankier A.T., Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P.,
RA   Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P.,
RA   Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N.,
RA   Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M.,
RA   Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I.,
RA   Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R.,
RA   Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C.,
RA   Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D.,
RA   Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S.,
RA   Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T.,
RA   Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A.,
RA   Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M.,
RA   Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G.,
RA   Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- SIMILARITY: Contains 1 TLC (TRAM/LAG1/CLN8) domain.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; AAFI02000047; EAL66163.1; -; Genomic_DNA.
DR   RefSeq; XP_640152.1; XM_635060.1.
DR   STRING; 44689.DDB_0230136; -.
DR   EnsemblProtists; DDB0230136; DDB0230136; DDB_G0282607.
DR   GeneID; 8623690; -.
DR   KEGG; ddi:DDB_G0282607; -.
DR   dictyBase; DDB_G0282607; crsA.
DR   eggNOG; COG5058; -.
DR   InParanoid; Q54S87; -.
DR   OMA; RFLENGW; -.
DR   GO; GO:0005783; C:endoplasmic reticulum; ISS:dictyBase.
DR   GO; GO:0016021; C:integral to membrane; ISS:dictyBase.
DR   GO; GO:0050291; F:sphingosine N-acyltransferase activity; ISS:dictyBase.
DR   GO; GO:0046513; P:ceramide biosynthetic process; ISS:dictyBase.
DR   InterPro; IPR006634; TLC-dom.
DR   Pfam; PF03798; TRAM_LAG1_CLN8; 1.
DR   SMART; SM00724; TLC; 1.
DR   PROSITE; PS50922; TLC; 1.
PE   4: Predicted;
KW   Complete proteome; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
SQ   SEQUENCE   341 AA;  40450 MW;  3E2ABDA17F072570 CRC64;
     MALDENGVSE IEWERLYNPD NSIFLSGRKL MSEVNAIIFL VVCTNIFFVI RFFFQHYVLK
     PIALSFNMRK SYTARFLENG WYTLYYISFF LIGSYVYSQE SWSIFPTMNI WLGWPTQPFS
     TLFRTYYLIE LSFYVHCTIA LFFETRRKDF NQMLTHHVAT FFLVGCSYWY RYHRIGIAIL
     WIHNIADIFL YSAKALNYIS KEVKNKTIQI ICDGLFVMFA VSFFVTRLIF FPFTLIKSSL
     TEAYYVSVEF PLFYPTNVAL LTLLILHMFW FFLIARIIYI KLFKSKDFDD IRSDSDEDEE
     VKPTQKGLEA EPTRTNKNTN NNKNNKLTQT KVSKAAQKKN E
//