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Database: UniProt/TrEMBL
Entry: Q5AFE9_CANAL
LinkDB: Q5AFE9_CANAL
Original site: Q5AFE9_CANAL 
ID   Q5AFE9_CANAL            Unreviewed;       765 AA.
AC   Q5AFE9; Q3MPX4;
DT   26-APR-2005, integrated into UniProtKB/TrEMBL.
DT   26-APR-2005, sequence version 1.
DT   07-SEP-2016, entry version 77.
DE   SubName: Full=DNA repair helicase RAD3 {ECO:0000313|EMBL:KHC71700.1};
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EAL01566.1};
GN   Name=RAD3 {ECO:0000313|CGD:CAL0000192893,
GN   ECO:0000313|EMBL:EAL01566.1};
GN   OrderedLocusNames=orf19.7119 {ECO:0000313|CGD:CAL0000192893};
GN   ORFNames=CaO19.7119 {ECO:0000313|EMBL:EAL01566.1}, I503_05016
GN   {ECO:0000313|EMBL:KHC80822.1}, W5Q_05059
GN   {ECO:0000313|EMBL:KHC71700.1};
OS   Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
OC   Saccharomycetes; Saccharomycetales; Debaryomycetaceae;
OC   Candida/Lodderomyces clade; Candida.
OX   NCBI_TaxID=237561 {ECO:0000313|EMBL:EAL01566.1, ECO:0000313|Proteomes:UP000000559};
RN   [1] {ECO:0000313|EMBL:EAL01566.1, ECO:0000313|Proteomes:UP000000559}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SC5314 {ECO:0000313|EMBL:EAL01566.1}, and SC5314 / ATCC
RC   MYA-2876 {ECO:0000313|Proteomes:UP000000559};
RX   PubMed=15123810; DOI=10.1073/pnas.0401648101;
RA   Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S.,
RA   Magee B.B., Newport G., Thorstenson Y.R., Agabian N., Magee P.T.,
RA   Davis R.W., Scherer S.;
RT   "The diploid genome sequence of Candida albicans.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004).
RN   [2] {ECO:0000313|EMBL:KHC71700.1, ECO:0000313|Proteomes:UP000030447, ECO:0000313|Proteomes:UP000030576}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SC5314 {ECO:0000313|Proteomes:UP000030447,
RC   ECO:0000313|Proteomes:UP000030576};
RG   The Broad Institute Genome Sequencing Platform;
RG   The Broad Institute Genome Sequencing Center for Infectious Disease;
RA   Cuomo C., Bennett R., Hirakawa M., Noverr M., Mitchell A., Young S.K.,
RA   Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L.,
RA   Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A., Gujja S.,
RA   Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C., Murphy C.,
RA   Pearson M., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA   Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Candida albicans SC5314.";
RL   Submitted (JUN-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: ATP + H(2)O = ADP + phosphate.
CC       {ECO:0000256|SAAS:SAAS00566177}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|SAAS:SAAS00553264}.
CC   -!- SIMILARITY: Contains helicase ATP-binding domain.
CC       {ECO:0000256|SAAS:SAAS00566183}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:EAL01566.1}.
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DR   EMBL; AACQ01000024; EAL01566.1; -; Genomic_DNA.
DR   EMBL; AJJF01000032; KHC71700.1; -; Genomic_DNA.
DR   EMBL; JTBX01000063; KHC80822.1; -; Genomic_DNA.
DR   RefSeq; XP_720409.1; XM_715316.1.
DR   RefSeq; XP_888639.1; XM_883546.1.
DR   EnsemblFungi; EAL01566; EAL01566; CaO19.7119.
DR   EnsemblFungi; KHC71700; KHC71700; W5Q_05059.
DR   EnsemblFungi; KHC80822; KHC80822; I503_05016.
DR   GeneID; 3638014; -.
DR   GeneID; 3704106; -.
DR   KEGG; cal:CaO19.7119; -.
DR   KEGG; cal:CaO19_7119; -.
DR   CGD; CAL0002854; orf19.7119.
DR   CGD; CAL0000192893; RAD3.
DR   KO; K10844; -.
DR   OrthoDB; EOG092C28I3; -.
DR   Proteomes; UP000000559; Unassembled WGS sequence.
DR   Proteomes; UP000030447; Unassembled WGS sequence.
DR   Proteomes; UP000030576; Unassembled WGS sequence.
DR   GO; GO:0000439; C:core TFIIH complex; IEA:EnsemblFungi.
DR   GO; GO:0005829; C:cytosol; IEA:EnsemblFungi.
DR   GO; GO:0005675; C:holo TFIIH complex; IEA:EnsemblFungi.
DR   GO; GO:0000112; C:nucleotide-excision repair factor 3 complex; IEA:EnsemblFungi.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:EnsemblFungi.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0043141; F:ATP-dependent 5'-3' DNA helicase activity; IEA:EnsemblFungi.
DR   GO; GO:0003684; F:damaged DNA binding; IEA:EnsemblFungi.
DR   GO; GO:0003678; F:DNA helicase activity; IDA:CGD.
DR   GO; GO:0000717; P:nucleotide-excision repair, DNA duplex unwinding; IEA:EnsemblFungi.
DR   GO; GO:0033683; P:nucleotide-excision repair, DNA incision; IEA:EnsemblFungi.
DR   GO; GO:0070816; P:phosphorylation of RNA polymerase II C-terminal domain; IEA:EnsemblFungi.
DR   GO; GO:0045951; P:positive regulation of mitotic recombination; IEA:EnsemblFungi.
DR   GO; GO:0010525; P:regulation of transposition, RNA-mediated; IEA:EnsemblFungi.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IEA:EnsemblFungi.
DR   Gene3D; 3.40.50.300; -; 2.
DR   InterPro; IPR006555; ATP-dep_Helicase_C.
DR   InterPro; IPR010614; DEAD_2.
DR   InterPro; IPR002464; DNA/RNA_helicase_DEAH_CS.
DR   InterPro; IPR013020; DNA_helicase_DNA-repair_Rad3.
DR   InterPro; IPR010643; HBB.
DR   InterPro; IPR014013; Helic_SF1/SF2_ATP-bd_DinG/Rad3.
DR   InterPro; IPR006554; Helicase-like_DEXD_c2.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR001945; RAD3/XPD.
DR   Pfam; PF06733; DEAD_2; 1.
DR   Pfam; PF06777; HBB; 1.
DR   Pfam; PF13307; Helicase_C_2; 1.
DR   PRINTS; PR00852; XRODRMPGMNTD.
DR   SMART; SM00488; DEXDc2; 1.
DR   SMART; SM00491; HELICc2; 1.
DR   SUPFAM; SSF52540; SSF52540; 6.
DR   TIGRFAMs; TIGR00604; rad3; 1.
DR   PROSITE; PS00690; DEAH_ATP_HELICASE; 1.
DR   PROSITE; PS51193; HELICASE_ATP_BIND_2; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|SAAS:SAAS00566225};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000000559,
KW   ECO:0000313|Proteomes:UP000030447, ECO:0000313|Proteomes:UP000030576};
KW   Helicase {ECO:0000256|SAAS:SAAS00566214, ECO:0000313|EMBL:KHC71700.1};
KW   Hydrolase {ECO:0000256|SAAS:SAAS00566224};
KW   Nucleotide-binding {ECO:0000256|SAAS:SAAS00566213};
KW   Nucleus {ECO:0000256|SAAS:SAAS00439093};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000559}.
FT   DOMAIN        7    286       Helicase ATP-binding.
FT                                {ECO:0000259|PROSITE:PS51193}.
FT   COILED      257    299       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   765 AA;  87783 MW;  6207839FC6C6ED43 CRC64;
     MKFFIDDLPV LFPYPRIYPE QYSYMCDIKK TLDVGGNCIL EMPSGTGKTV SLLSLTVAYQ
     MHYPEHRKIV YCSRTMSEIE KALIELHKLM EFRANELGEV EDFRGLGLTS RKNLCLHPTI
     SKERKGVVVD EKCRRITNGQ LKEKIEKGVP TEDSLCSFHE KLYDLEPHNL VPPGVYSFDA
     LIKYCKEEGT CPYFTVRRMI PFCNIIIYSY HYLLDPKIAE RVSRELSKDS IVIFDEAHNI
     DNVCIESLSL DLTDETLKKA SRGANKLGEA IEDMKAQDSE KLQNEYEQLV EGLRQAEIAR
     DQELFMANPV LPQDLLDEAI PGNIRKGEHF IAFLKRFIEY LKTRMKVLHV ISETPTSFLQ
     HLKELTYIER KPLRFCSERL SLLVRTLEVT EIDDFNALKD IATFATLVST YDSGFQLILE
     PYETEGSTVP NPILHFTCLD ASIAIKPVFD RFSSVIITSG TISPLDMYPK MLKFETVIQE
     SYAMTLARRS FLPMIVTKGS DQVSISSRFE IRNDPSVVRN YGSLLIEFAK ITPDGMVVFF
     PSYLYMESII SMWQSMGVLD EVWKHKLILV ETPDAQETSL ALETYRKACS NGRGAVLLSV
     ARGKVSEGID FDHHYGRTVL MIGIPFQYTE SRILKARLEF MRDHFQIKEN DFLSFDAMRH
     AAQCLGRVLR GKDDYGIMVL ADRRFARKKN QLPKWIAQAL NDSDTNLSTD MALATAKKFL
     RSLAQPTNPK DSEGVSIWNI EQLQEYQQQF QKDEMDIDEE DLDLL
//
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