ID   Q5KGT1_CRYNJ            Unreviewed;       836 AA.
AC   Q5KGT1;
DT   15-FEB-2005, integrated into UniProtKB/TrEMBL.
DT   15-FEB-2005, sequence version 1.
DT   27-MAR-2024, entry version 84.
DE   RecName: Full=Galactose oxidase {ECO:0008006|Google:ProtNLM};
GN   OrderedLocusNames=CNE02450 {ECO:0000313|EMBL:AAW43641.1};
OS   Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC
OS   MYA-565) (Filobasidiella neoformans).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC   Tremellales; Cryptococcaceae; Cryptococcus;
OC   Cryptococcus neoformans species complex.
OX   NCBI_TaxID=214684 {ECO:0000313|EMBL:AAW43641.1, ECO:0000313|Proteomes:UP000002149};
RN   [1] {ECO:0000313|EMBL:AAW43641.1, ECO:0000313|Proteomes:UP000002149}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JEC21 / ATCC MYA-565 {ECO:0000313|Proteomes:UP000002149};
RX   PubMed=15653466; DOI=10.1126/science.1103773;
RA   Loftus B.J., Fung E., Roncaglia P., Rowley D., Amedeo P., Bruno D.,
RA   Vamathevan J., Miranda M., Anderson I.J., Fraser J.A., Allen J.E.,
RA   Bosdet I.E., Brent M.R., Chiu R., Doering T.L., Donlin M.J., D'Souza C.A.,
RA   Fox D.S., Grinberg V., Fu J., Fukushima M., Haas B.J., Huang J.C.,
RA   Janbon G., Jones S.J., Koo H.L., Krzywinski M.I., Kwon-Chung J.K.,
RA   Lengeler K.B., Maiti R., Marra M.A., Marra R.E., Mathewson C.A.,
RA   Mitchell T.G., Pertea M., Riggs F.R., Salzberg S.L., Schein J.E.,
RA   Shvartsbeyn A., Shin H., Shumway M., Specht C.A., Suh B.B., Tenney A.,
RA   Utterback T.R., Wickes B.L., Wortman J.R., Wye N.H., Kronstad J.W.,
RA   Lodge J.K., Heitman J., Davis R.W., Fraser C.M., Hyman R.W.;
RT   "The genome of the basidiomycetous yeast and human pathogen Cryptococcus
RT   neoformans.";
RL   Science 307:1321-1324(2005).
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DR   EMBL; AE017345; AAW43641.1; -; Genomic_DNA.
DR   RefSeq; XP_570948.1; XM_570948.1.
DR   AlphaFoldDB; Q5KGT1; -.
DR   STRING; 214684.Q5KGT1; -.
DR   PaxDb; 214684-Q5KGT1; -.
DR   EnsemblFungi; AAW43641; AAW43641; CNE02450.
DR   GeneID; 3257833; -.
DR   KEGG; cne:CNE02450; -.
DR   VEuPathDB; FungiDB:CNE02450; -.
DR   eggNOG; ENOG502SA7Y; Eukaryota.
DR   HOGENOM; CLU_341313_0_0_1; -.
DR   InParanoid; Q5KGT1; -.
DR   OMA; NWEEIDF; -.
DR   OrthoDB; 1468171at2759; -.
DR   Proteomes; UP000002149; Chromosome 5.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 2.120.10.80; Kelch-type beta propeller; 2.
DR   InterPro; IPR011043; Gal_Oxase/kelch_b-propeller.
DR   InterPro; IPR015915; Kelch-typ_b-propeller.
DR   PANTHER; PTHR23244:SF503; -; 1.
DR   PANTHER; PTHR23244; KELCH REPEAT DOMAIN; 1.
DR   Pfam; PF13854; Kelch_5; 1.
DR   SUPFAM; SSF50965; Galactose oxidase, central domain; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002149};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        405..427
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          498..524
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          759..836
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        505..519
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        764..826
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   836 AA;  88326 MW;  902AAA226C60179F CRC64;
     MTRKIQKTST VTSAAAALAA LPRAFASTPA ARWGHQGVYV KSKKAMYIVG GETSASGYQI
     TNEVLVLSLN SSSPSFTTGS SDGLPAHAFA SAALSNDENS LVVMGGMTSD CSSDGLAHTL
     DLSNDDEWTS TSPSKFTRRR GAGMAWVDNN STYGEFMVIG GIADSYSCSS STSAYTAADV
     LSLPLSSSAL VSSRSLPKSL TGSTLAVSDF GLASDSSGKI YLAGGQSSSG DLVSLDTIGV
     WDSTNGWQSQ TTSGDVPDGR VGASLVAHPN LDMLVLHGGS VSNSTSGSYS STSLLAFLNT
     TTFEWSTPSN LQPPSSSAAS YHSAVMTDQG VMISAFGLSA SGAPRSDVYY LDLRDTAKTS
     WAWKSSWNSD MLEAYSGSST SANGTANGVT AADAKSSSSM SSKKLASIIV PILVVALLLT
     PLIVYLIRRR VRVIKKRRMA QHFSFSSQED SGAFNFRTPF NQYLAKRRSE GQFPVGGDSS
     EREGNFVTGV TGTLGRMVSR LSNRSSDSGH EDARESGEEG QRQMAQVGQR VMINLDDAQP
     MNWEEIDFGL GKLDESKGHG SSHDANSRAF VQDRQNSVPS AAEGYTADQL YALEEVPSEA
     ENVHAQIIPN TLVTAYPVME PSPAYTPHQA GDWTKLQEDL TQKPAFQKIS PSAQLRSHSH
     PAPAAISPFA DPTLASETLA INRSSSLTRT ISQAPSIAPS IPPFEFQRAE SPGGTITLVN
     PQTAAQTQEI LPFASAKGAN GTHRSVSQPI TRQLIDGRLA RRESAPSSSG SHSGSESGEA
     QPTKTLSHAK GRTVSANHAP QVRRSSSSSA GTVKYPSASR RKTQLRVVNL TESEEH
//