ID   Q5KM78_CRYNJ            Unreviewed;       488 AA.
AC   Q5KM78;
DT   15-FEB-2005, integrated into UniProtKB/TrEMBL.
DT   15-FEB-2005, sequence version 1.
DT   01-MAY-2013, entry version 48.
DE   SubName: Full=Hexokinase, putative;
GN   OrderedLocusNames=CNB02660;
OS   Cryptococcus neoformans var. neoformans serotype D (strain JEC21 /
OS   ATCC MYA-565) (Filobasidiella neoformans).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina;
OC   Tremellomycetes; Tremellales; Tremellaceae; Filobasidiella;
OC   Filobasidiella/Cryptococcus neoformans species complex.
OX   NCBI_TaxID=214684;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JEC21 / ATCC MYA-565;
RX   PubMed=15653466; DOI=10.1126/science.1103773;
RA   Loftus B.J., Fung E., Roncaglia P., Rowley D., Amedeo P., Bruno D.,
RA   Vamathevan J., Miranda M., Anderson I.J., Fraser J.A., Allen J.E.,
RA   Bosdet I.E., Brent M.R., Chiu R., Doering T.L., Donlin M.J.,
RA   D'Souza C.A., Fox D.S., Grinberg V., Fu J., Fukushima M., Haas B.J.,
RA   Huang J.C., Janbon G., Jones S.J.M., Koo H.L., Krzywinski M.I.,
RA   Kwon-Chung K.J., Lengeler K.B., Maiti R., Marra M.A., Marra R.E.,
RA   Mathewson C.A., Mitchell T.G., Pertea M., Riggs F.R., Salzberg S.L.,
RA   Schein J.E., Shvartsbeyn A., Shin H., Shumway M., Specht C.A.,
RA   Suh B.B., Tenney A., Utterback T.R., Wickes B.L., Wortman J.R.,
RA   Wye N.H., Kronstad J.W., Lodge J.K., Heitman J., Davis R.W.,
RA   Fraser C.M., Hyman R.W.;
RT   "The genome of the basidiomycetous yeast and human pathogen
RT   Cryptococcus neoformans.";
RL   Science 307:1321-1324(2005).
CC   -!- SIMILARITY: Belongs to the hexokinase family.
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DR   EMBL; AE017342; AAW41546.1; -; Genomic_DNA.
DR   RefSeq; XP_568853.1; XM_568853.1.
DR   UniGene; Fne.7304; -.
DR   ProteinModelPortal; Q5KM78; -.
DR   STRING; 214684.CNB02660; -.
DR   GeneID; 3255870; -.
DR   KEGG; cne:CNB02660; -.
DR   HOGENOM; HOG000162670; -.
DR   KO; K00844; -.
DR   OrthoDB; EOG4H75M2; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004396; F:hexokinase activity; IEA:InterPro.
DR   GO; GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
DR   InterPro; IPR001312; Hexokinase.
DR   InterPro; IPR022673; Hexokinase_C.
DR   InterPro; IPR019807; Hexokinase_CS.
DR   InterPro; IPR022672; Hexokinase_N.
DR   PANTHER; PTHR19443; PTHR19443; 1.
DR   Pfam; PF00349; Hexokinase_1; 1.
DR   Pfam; PF03727; Hexokinase_2; 1.
DR   PRINTS; PR00475; HEXOKINASE.
DR   PROSITE; PS00378; HEXOKINASES; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Glycolysis; Kinase;
KW   Nucleotide-binding; Reference proteome; Transferase.
SQ   SEQUENCE   488 AA;  53493 MW;  9742FA1095DCC4B8 CRC64;
     MTLPEVCKQF EPYFILDDAK LVDIVKHFRK EMEEGLASYG KDMAMIPTFV TGVPDGTEEG
     VFLALDLGGT NLRVCLILLQ GHNQFKIKQQ KYKVSEELKT GQARVLFDYI AESVDNFLTE
     VESHEDIAIP ATGEPMHLGF TFSFPVEQTA IDAGKLLTWT KGFNTKNAIG HDVVRLLQDA
     FDRKHMHVRC SALVNDTVGT LLSRSYQSGP ALIGAIFGTG TNGAYIDKTR TISKLGKEKI
     EDAEEGGEHA GEFMVVNMEW GAFDNKRQCL PISIFDNKLD RESINPRKQA FEKLVSGMYL
     GEITRNMLLY MIDSSLLFGG HSSEIINTHY GFDTSFVSGI EGISSPEEVK KLIVKELKVD
     PKHVTDKCPE IVQWAVRLVS DRACKLAACA IAAVVLHTGN DKAPEGEEDK GVDVGVDGSV
     AEFLPMFSER VMAALKAILG EKSAARVKLG LAKDGSGVGA ALTALQAKKA LDRRSDRSIK
     FVPGERGP
//