ID Q6LX47_METMP Unreviewed; 387 AA.
AC Q6LX47;
DT 05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2004, sequence version 1.
DT 27-MAR-2024, entry version 97.
DE SubName: Full=Pyruvate oxidoreductase (Synthase) subunit alpha {ECO:0000313|EMBL:CAF31061.1};
DE EC=1.2.7.1 {ECO:0000313|EMBL:CAF31061.1};
GN Name=porA {ECO:0000313|EMBL:CAF31061.1};
GN OrderedLocusNames=MMP1505 {ECO:0000313|EMBL:CAF31061.1};
OS Methanococcus maripaludis (strain S2 / LL).
OC Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC Methanococcaceae; Methanococcus.
OX NCBI_TaxID=267377 {ECO:0000313|Proteomes:UP000000590};
RN [1] {ECO:0000313|EMBL:CAF31061.1, ECO:0000313|Proteomes:UP000000590}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S2 / LL {ECO:0000313|Proteomes:UP000000590};
RX PubMed=15466049; DOI=10.1128/JB.186.20.6956-6969.2004;
RA Hendrickson E.L., Kaul R., Zhou Y., Bovee D., Chapman P., Chung J.,
RA Conway de Macario E., Dodsworth J.A., Gillett W., Graham D.E., Hackett M.,
RA Haydock A.K., Kang A., Land M.L., Levy R., Lie T.J., Major T.A.,
RA Moore B.C., Porat I., Palmeiri A., Rouse G., Saenphimmachak C., Soll D.,
RA Van Dien S., Wang T., Whitman W.B., Xia Q., Zhang Y., Larimer F.W.,
RA Olson M.V., Leigh J.A.;
RT "Complete genome sequence of the genetically tractable hydrogenotrophic
RT methanogen Methanococcus maripaludis.";
RL J. Bacteriol. 186:6956-6969(2004).
CC -!- SUBUNIT: Heterotetramer of one alpha, one beta, one delta and one gamma
CC chain. {ECO:0000256|ARBA:ARBA00011595}.
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DR EMBL; BX950229; CAF31061.1; -; Genomic_DNA.
DR RefSeq; WP_011171449.1; NC_005791.1.
DR AlphaFoldDB; Q6LX47; -.
DR STRING; 267377.MMP1505; -.
DR EnsemblBacteria; CAF31061; CAF31061; MMP1505.
DR GeneID; 2761618; -.
DR KEGG; mmp:MMP1505; -.
DR PATRIC; fig|267377.15.peg.1542; -.
DR eggNOG; arCOG01608; Archaea.
DR HOGENOM; CLU_002569_5_0_2; -.
DR OrthoDB; 372068at2157; -.
DR Proteomes; UP000000590; Chromosome.
DR GO; GO:0019164; F:pyruvate synthase activity; IEA:UniProtKB-EC.
DR CDD; cd07034; TPP_PYR_PFOR_IOR-alpha_like; 1.
DR Gene3D; 3.40.50.920; -; 1.
DR Gene3D; 3.40.50.970; -; 1.
DR InterPro; IPR033412; PFOR_II.
DR InterPro; IPR002880; Pyrv_Fd/Flavodoxin_OxRdtase_N.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR009014; Transketo_C/PFOR_II.
DR NCBIfam; NF040682; PorA_Arch; 1.
DR PANTHER; PTHR32154; PYRUVATE-FLAVODOXIN OXIDOREDUCTASE-RELATED; 1.
DR PANTHER; PTHR32154:SF0; PYRUVATE-FLAVODOXIN OXIDOREDUCTASE-RELATED; 1.
DR Pfam; PF17147; PFOR_II; 1.
DR Pfam; PF01855; POR_N; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
DR SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000313|EMBL:CAF31061.1};
KW Pyruvate {ECO:0000313|EMBL:CAF31061.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000590}.
FT DOMAIN 15..239
FT /note="Pyruvate flavodoxin/ferredoxin oxidoreductase
FT pyrimidine binding"
FT /evidence="ECO:0000259|Pfam:PF01855"
FT DOMAIN 264..364
FT /note="Pyruvate:ferredoxin oxidoreductase core"
FT /evidence="ECO:0000259|Pfam:PF17147"
SQ SEQUENCE 387 AA; 42248 MW; 32FD1D6485D3A111 CRC64;
MCEVKVITGT SAAAEAAKLA DVDVIAAYPI TPQTTCVEKL ADFVANGELN AEYIKVESEH
SAMSASIGAS AAGARAFTAT SSQGLALMHE VLFSAAGMRV PVVMMNANRA LSAPINIWND
QQDSLSQRDT GWIQLYAEDN QEVLDLVIQA FKIAEDEKVL LPVMVNLDGF ILTHTVEPVT
VPKQENVLDF IGTYEPKHAY LDPKKPMTQG ALGDPNYYME TRYAIETAMR NAEKVIADVH
DAFAEKFNRA YGNGLIESYN LEKAENVIIA MGSICGTIKD IIDLKKKEGV EIGLLKIRCY
RPLPVEMIKD ALKNAKNVAI LDKSISLGMN KGAIYADVAS HLKDKKTVNY IVGLGGRDIT
PEDILGIYDD VEISEDGKTN WIGLKEE
//
