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Database: UniProt/TrEMBL
Entry: Q6TNF3_BOVIN
LinkDB: Q6TNF3_BOVIN
Original site: Q6TNF3_BOVIN 
ID   Q6TNF3_BOVIN            Unreviewed;       846 AA.
AC   Q6TNF3;
DT   05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2005, sequence version 4.
DT   05-JUL-2017, entry version 82.
DE   SubName: Full=Tranglutaminase 1 {ECO:0000313|EMBL:AAR26246.2};
GN   Name=TGM1 {ECO:0000313|EMBL:AAR26246.2};
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;
OC   Pecora; Bovidae; Bovinae; Bos.
OX   NCBI_TaxID=9913 {ECO:0000313|EMBL:AAR26246.2};
RN   [1] {ECO:0000313|EMBL:AAR26246.2}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Skin biopsy {ECO:0000313|EMBL:AAR26246.2};
RA   Longeri M., Dardano S., Molteni L., Polli M., Parma P., Sironi G.,
RA   Zanotti M., Succi G.;
RT   "Ichthyosis disorder in Chianina cattle: identification of the
RT   inherited transmission by pedigree analysis and sequencing of TGM1
RT   candidate gene.";
RL   (In) Unknown A. (eds.);
RL   PROCEEDINGS OF THE 29TH CONFERENCE OF THE INTERNATIONAL SOCIETY OF
RL   ANIMAL GENETICS ISAG, pp.0-0, Blackwell Publishing, Edinburgh, United
RL   Kingdom (2004).
RN   [2] {ECO:0000313|EMBL:AAR26246.2}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Skin biopsy {ECO:0000313|EMBL:AAR26246.2};
RA   Longeri M., Parma P., Molteni L., Dardano S., Filippini F.,
RA   Zanotti M.;
RL   Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; AY676606; AAR26246.2; -; mRNA.
DR   RefSeq; NP_001010991.1; NM_001010991.1.
DR   UniGene; Bt.736; -.
DR   ProteinModelPortal; Q6TNF3; -.
DR   PaxDb; Q6TNF3; -.
DR   PRIDE; Q6TNF3; -.
DR   GeneID; 407997; -.
DR   KEGG; bta:407997; -.
DR   CTD; 7051; -.
DR   eggNOG; ENOG410IFMV; Eukaryota.
DR   eggNOG; ENOG410XQEZ; LUCA.
DR   HOGENOM; HOG000231695; -.
DR   HOVERGEN; HBG004342; -.
DR   KO; K05619; -.
DR   GO; GO:0003810; F:protein-glutamine gamma-glutamyltransferase activity; IEA:InterPro.
DR   GO; GO:0018149; P:peptide cross-linking; IEA:InterPro.
DR   Gene3D; 2.60.40.10; -; 3.
DR   Gene3D; 3.90.260.10; -; 1.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR002931; Transglutaminase-like.
DR   InterPro; IPR023608; Transglutaminase_animal.
DR   InterPro; IPR013808; Transglutaminase_AS.
DR   InterPro; IPR008958; Transglutaminase_C.
DR   InterPro; IPR001102; Transglutaminase_N.
DR   Pfam; PF00927; Transglut_C; 2.
DR   Pfam; PF01841; Transglut_core; 1.
DR   Pfam; PF00868; Transglut_N; 1.
DR   PIRSF; PIRSF000459; TGM_EBP42; 1.
DR   SMART; SM00460; TGc; 1.
DR   SUPFAM; SSF49309; SSF49309; 2.
DR   SUPFAM; SSF81296; SSF81296; 1.
DR   PROSITE; PS00547; TRANSGLUTAMINASES; 1.
PE   2: Evidence at transcript level;
FT   DOMAIN      399    492       TGc. {ECO:0000259|SMART:SM00460}.
FT   ACT_SITE    407    407       {ECO:0000256|PIRSR:PIRSR000459-1}.
FT   ACT_SITE    466    466       {ECO:0000256|PIRSR:PIRSR000459-1}.
FT   ACT_SITE    489    489       {ECO:0000256|PIRSR:PIRSR000459-1}.
SQ   SEQUENCE   846 AA;  93105 MW;  31B4A675365C4849 CRC64;
     MPSPTPSSGG PRSDVGRWGG NPWQPPTTPS PEPEPEPDRR SRRGGRSFWA RCCGCCSCRN
     TEDDDWGPER HGDRGGRGSG SRNRRPDSRG SDSRQPGSRD SRRPGSRDSR RPGSRDSRRP
     GSRGSAVNAA GDGTIREGML VVTGVDLLSS RSDQNRREHH TDEFEYDELI LRRGQPFQMV
     LFLSRPYESS DHVTLELCIG NNPEVGKGTH VIIPVGKGGS GGWKAQVTKS SGQNLNLRVH
     TSPNAIIGKF QFTIRTRCEA GEFQLPFDPR NEIYILFNPW CPEDIVYVDH EDWRQEYVLN
     ESGRIYYGTE AQIGERTWNY GQFDHGVLDA CLYILDRRGM PYGGRGDPVS VSRVISAMVN
     SLDDNGVLIG NWSGDYSRGT NPSAWVGSVE ILLSYLRTGN SVPFGQCWVF AGVTTTVLRC
     LGLATRTVTN FNSAHDTDTS LTMDIYFDEN MKPLEHLNHD SVWNFHVWND CWMKRPDLPS
     GFDGWQVVDA TPQETSSGIF CCGPCSVQSI KNGLVYMKYD TPFIFAEVNS DKVYWQRQDD
     GSFKIVYVEE KAIGSLIITK AIGSNMREDI THTYKHPEGS EAERKAVETA AAHGSKPNVY
     ATRDSAEDVA VQVEAQDAVM GQDLMVSVVL TNRGSSLRTV KLHLYLSVTF YTGVTGSVFK
     ESKKEVVLAP GASERVTMPV AYKEYRVHLV DQGAMLLNIS GHVKENGQVL AKQHTFRLRT
     PDLSLTLLGA AVVGQECEVQ IVFKNPLPVT LTNVVFRLEG SGLQRPKILN VGDIGGNETV
     TLRQTFVPVR PGPRQLIASL DSPQLSQVHG VIQVDVAPAS GGGAFSDIRG SGRSGETIPM
     ASRGGA
//
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