ID Q73FQ2_WOLPM Unreviewed; 515 AA.
AC Q73FQ2;
DT 05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2004, sequence version 1.
DT 27-MAR-2024, entry version 99.
DE SubName: Full=Penicillin-binding protein {ECO:0000313|EMBL:AAS14917.1};
GN OrderedLocusNames=WD_1273 {ECO:0000313|EMBL:AAS14917.1};
OS Wolbachia pipientis wMel.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rickettsiales;
OC Anaplasmataceae; Wolbachieae; Wolbachia.
OX NCBI_TaxID=163164 {ECO:0000313|EMBL:AAS14917.1, ECO:0000313|Proteomes:UP000008215};
RN [1] {ECO:0000313|EMBL:AAS14917.1, ECO:0000313|Proteomes:UP000008215}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WMel {ECO:0000313|EMBL:AAS14917.1};
RX PubMed=15024419; DOI=10.1371/journal.pbio.0020069;
RA Wu M., Sun L.V., Vamathevan J., Riegler M., Deboy R., Brownlie J.C.,
RA McGraw E.A., Martin W., Esser C., Ahmadinejad N., Wiegand C., Madupu R.,
RA Beanan M.J., Brinkac L.M., Daugherty S.C., Durkin A.S., Kolonay J.F.,
RA Nelson W.C., Mohamoud Y., Lee P., Berry K., Young M.B., Utterback T.,
RA Weidman J., Nierman W.C., Paulsen I.T., Nelson K.E., Tettelin H.,
RA O'Neill S.L., Eisen J.A.;
RT "Phylogenomics of the reproductive parasite Wolbachia pipientis wMel: a
RT streamlined genome overrun by mobile genetic elements.";
RL PLoS Biol. 2:327-341(2004).
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DR EMBL; AE017196; AAS14917.1; -; Genomic_DNA.
DR RefSeq; WP_010963147.1; NZ_OX384529.1.
DR AlphaFoldDB; Q73FQ2; -.
DR EnsemblBacteria; AAS14917; AAS14917; WD_1273.
DR GeneID; 70036739; -.
DR KEGG; wol:WD_1273; -.
DR eggNOG; COG0768; Bacteria.
DR Proteomes; UP000008215; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016757; F:glycosyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR Gene3D; 3.30.450.330; -; 1.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 4: Predicted;
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transferase {ECO:0000256|ARBA:ARBA00022676};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..34
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 54..157
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 211..502
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 515 AA; 57171 MW; 67BDC01EA6DB6E64 CRC64;
MQALLKNKLR SLCFIVPLFI FYIIIIFRIF SLTFDQLTTS ENFRKDNIVH KQPDILDRNG
VVIATNVPTT SLYIDATKVK NPESIAAQLC STLHDLEYKN LYRVLTSEKK FAWIKRHLTP
KELLAIKNAG VPGVNFDDDI KRIYPHSNLF SHVLGYTDID GNGIAGVEAY ISKNNEQEKP
IILSLDTRVQ SIVHEELTKA VRRYQALGGV GIVLNVRNSE VISMVSLPDF NPNLQNKAED
VQKFNRASLG VYEMGSVLKY FTIAAALDAN ATKTSDLYDV STPITIGKYK IQDFHKSKIP
KITVQDIFVK SSNIGAAKIA VKLGIEKQVE YFKAMKLFSP LKIEIPEKST PIIPDKWSET
TLITASYGYG IAVTPIHLAQ TAAALINNGI FHNATLMLNK RSIGEQIISR RTSREMRKLL
RAAVTDGTGR KAKIKAYSIG GKTGSAEKVV DGKYSKDANI ASFIGVLTML DPRYIVLIAI
DEPQGMHHTG GIIAAPIVKN IINRIAPILN VTPEM
//
