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Database: UniProt/TrEMBL
Entry: Q7CGA8_YERPE
LinkDB: Q7CGA8_YERPE
Original site: Q7CGA8_YERPE 
ID   Q7CGA8_YERPE            Unreviewed;       587 AA.
AC   Q7CGA8; Q74Q70;
DT   05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2004, sequence version 1.
DT   06-JUL-2016, entry version 84.
DE   SubName: Full=Penicillin-binding protein 3 {ECO:0000313|EMBL:AAS63783.1};
DE   SubName: Full=Peptidoglycan synthetase {ECO:0000313|EMBL:AAM87180.1};
GN   Name=ftsI {ECO:0000313|EMBL:AAM87180.1};
GN   OrderedLocusNames=y3632 {ECO:0000313|EMBL:AAM87180.1}, YP_3635
GN   {ECO:0000313|EMBL:AAS63783.1}, YPO0549 {ECO:0000313|EMBL:CAL19228.1};
OS   Yersinia pestis.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Yersinia.
OX   NCBI_TaxID=632 {ECO:0000313|Proteomes:UP000002490};
RN   [1] {ECO:0000313|EMBL:CAL19228.1, ECO:0000313|Proteomes:UP000000815}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CO-92 / Biovar Orientalis {ECO:0000313|Proteomes:UP000000815},
RC   and CO92 {ECO:0000313|EMBL:CAL19228.1};
RX   PubMed=11586360; DOI=10.1038/35097083;
RA   Parkhill J., Wren B.W., Thomson N.R., Titball R.W., Holden M.T.G.,
RA   Prentice M.B., Sebaihia M., James K.D., Churcher C., Mungall K.L.,
RA   Baker S., Basham D., Bentley S.D., Brooks K., Cerdeno-Tarraga A.M.,
RA   Chillingworth T., Cronin A., Davies R.M., Davis P., Dougan G.,
RA   Feltwell T., Hamlin N., Holroyd S., Jagels K., Leather S.,
RA   Karlyshev A.V., Moule S., Oyston P.C.F., Quail M., Rutherford K.,
RA   Simmonds M., Skelton J., Stevens K., Whitehead S., Barrell B.G.;
RT   "Genome sequence of Yersinia pestis, the causative agent of plague.";
RL   Nature 413:523-527(2001).
RN   [2] {ECO:0000313|EMBL:AAM87180.1, ECO:0000313|Proteomes:UP000002490}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KIM {ECO:0000313|EMBL:AAM87180.1}, and KIM10+ / Biovar
RC   Mediaevalis {ECO:0000313|Proteomes:UP000002490};
RX   PubMed=12142430; DOI=10.1128/JB.184.16.4601-4611.2002;
RA   Deng W., Burland V., Plunkett G.III., Boutin A., Mayhew G.F., Liss P.,
RA   Perna N.T., Rose D.J., Mau B., Zhou S., Schwartz D.C.,
RA   Fetherston J.D., Lindler L.E., Brubaker R.R., Plana G.V.,
RA   Straley S.C., McDonough K.A., Nilles M.L., Matson J.S., Blattner F.R.,
RA   Perry R.D.;
RT   "Genome sequence of Yersinia pestis KIM.";
RL   J. Bacteriol. 184:4601-4611(2002).
RN   [3] {ECO:0000313|EMBL:AAS63783.1, ECO:0000313|Proteomes:UP000001019}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=91001 {ECO:0000313|EMBL:AAS63783.1}, and 91001 / Biovar
RC   Mediaevalis {ECO:0000313|Proteomes:UP000001019};
RX   PubMed=15368893; DOI=10.1093/dnares/11.3.179;
RA   Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D.,
RA   Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z.,
RA   Jin L., Dai R., Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J.,
RA   Yang H., Wang J., Huang P., Yang R.;
RT   "Complete genome sequence of Yersinia pestis strain 91001, an isolate
RT   avirulent to humans.";
RL   DNA Res. 11:179-197(2004).
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DR   EMBL; AE009952; AAM87180.1; -; Genomic_DNA.
DR   EMBL; AE017042; AAS63783.1; -; Genomic_DNA.
DR   EMBL; AL590842; CAL19228.1; -; Genomic_DNA.
DR   PIR; AB0068; AB0068.
DR   RefSeq; WP_002210440.1; NZ_LQAY01000071.1.
DR   RefSeq; YP_002345620.1; NC_003143.1.
DR   STRING; 187410.y3632; -.
DR   DNASU; 1148579; -.
DR   EnsemblBacteria; AAM87180; AAM87180; y3632.
DR   EnsemblBacteria; AAS63783; AAS63783; YP_3635.
DR   EnsemblBacteria; KNX87033; KNX87033; ACX54_179.
DR   EnsemblBacteria; KNX88811; KNX88811; ACX52_1538.
DR   GeneID; 1173393; -.
DR   KEGG; ype:YPO0549; -.
DR   KEGG; ypk:y3632; -.
DR   KEGG; ypl:CH46_368; -.
DR   KEGG; ypm:YP_3635; -.
DR   KEGG; ypv:BZ15_3025; -.
DR   KEGG; ypw:CH59_1315; -.
DR   eggNOG; ENOG4105CJN; Bacteria.
DR   eggNOG; COG0768; LUCA.
DR   HOGENOM; HOG000049554; -.
DR   KO; K03587; -.
DR   OMA; FVINREE; -.
DR   OrthoDB; EOG6N0HHV; -.
DR   BioCyc; YPES214092:GKDD-543-MONOMER; -.
DR   Proteomes; UP000000815; Chromosome.
DR   Proteomes; UP000001019; Chromosome.
DR   Proteomes; UP000002490; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR   Gene3D; 3.40.710.10; -; 1.
DR   InterPro; IPR012338; Beta-lactam/transpept-like.
DR   InterPro; IPR005311; PBP_dimer.
DR   InterPro; IPR001460; PCN-bd_Tpept.
DR   Pfam; PF03717; PBP_dimer; 1.
DR   Pfam; PF00905; Transpeptidase; 1.
DR   SUPFAM; SSF56519; SSF56519; 1.
DR   SUPFAM; SSF56601; SSF56601; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000000815,
KW   ECO:0000313|Proteomes:UP000001019, ECO:0000313|Proteomes:UP000002490};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000815};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     21     43       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       67    219       PBP_dimer. {ECO:0000259|Pfam:PF03717}.
FT   DOMAIN      259    553       Transpeptidase. {ECO:0000259|Pfam:
FT                                PF00905}.
SQ   SEQUENCE   587 AA;  63639 MW;  93070618BAA0511C CRC64;
     MKTARPGKLK RQEEQASFIS WRFALLCGCI LLALVGLIMR TAYLQVINPD KLVREGDMRS
     LRVQEVPTAR GMISDRSGRP LAVSVPVNAV WADPKELIEQ GGISLDTRWK ALSDALEIPL
     DQLATRINAN PKGRFVYLAR QVNPAIGDYI RKLKLPGIHL RQESRRYYPA GQVMAHIIGV
     TNIDGQGIEG VEKSFDRWLT GQPGERTVRK DHYGRVIEDI SSVDSQAAHN LVLSVDERLQ
     ALVYRELNNA VAFNKAESGT AVLVDVNTGE VLAMANSPSY NPNNLTGTPK DAMRNRAITD
     IFEPGSTVKP MVVMTALQHG VVKENSVLNT LPYFVNGHQI KDVARYAELS VTGILQKSSN
     VGVSKLALAM PSSALVDTYS RFGFGKATNL GLVGESSGLY PKKQRWSDIE RATFSFGYGL
     MVTPLQLARV YATIGSMGVY RPLSITRVDP PVAGERIFPE PLVRTVVHMM ESVALPGGGG
     TKAAIKGYRI AIKTGTAKKV GPDGKYMDRY LAYTAGVAPA SNPRFALVVV INDPQAGKYY
     GGAVSAPVFG AIMGGVLRTM NIEPDALPTG DKSELVINTK EGSGGRS
//
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