ID   Q7MLY7_VIBVY            Unreviewed;       482 AA.
AC   Q7MLY7;
DT   15-DEC-2003, integrated into UniProtKB/TrEMBL.
DT   15-DEC-2003, sequence version 1.
DT   01-MAY-2013, entry version 71.
DE   RecName: Full=Pyruvate kinase;
DE            EC=2.7.1.40;
GN   OrderedLocusNames=VV1289;
OS   Vibrio vulnificus (strain YJ016).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales;
OC   Vibrionaceae; Vibrio.
OX   NCBI_TaxID=196600;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YJ016;
RX   PubMed=14656965; DOI=10.1101/gr.1295503;
RA   Chen C.Y., Wu K.M., Chang Y.C., Chang C.H., Tsai H.C., Liao T.L.,
RA   Liu Y.M., Chen H.J., Shen A.B., Li J.C., Su T.L., Shao C.P., Lee C.T.,
RA   Hor L.I., Tsai S.F.;
RT   "Comparative genome analysis of Vibrio vulnificus, a marine
RT   pathogen.";
RL   Genome Res. 13:2577-2587(2003).
CC   -!- CATALYTIC ACTIVITY: ATP + pyruvate = ADP + phosphoenolpyruvate.
CC   -!- PATHWAY: Carbohydrate degradation; glycolysis; pyruvate from D-
CC       glyceraldehyde 3-phosphate: step 5/5.
CC   -!- SIMILARITY: Belongs to the pyruvate kinase family.
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DR   EMBL; BA000037; BAC94053.1; -; Genomic_DNA.
DR   RefSeq; NP_934082.1; NC_005139.1.
DR   HSSP; P14178; 1E0T.
DR   ProteinModelPortal; Q7MLY7; -.
DR   STRING; 196600.VV1289; -.
DR   EnsemblBacteria; BAC94053; BAC94053; BAC94053.
DR   GeneID; 2624093; -.
DR   KEGG; vvy:VV1289; -.
DR   PATRIC; 20169390; VBIVibVul40472_1282.
DR   eggNOG; COG0469; -.
DR   HOGENOM; HOG000021558; -.
DR   KO; K00873; -.
DR   OMA; TVRNDEN; -.
DR   ProtClustDB; CLSK241348; -.
DR   UniPathway; UPA00109; UER00188.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0030955; F:potassium ion binding; IEA:InterPro.
DR   GO; GO:0004743; F:pyruvate kinase activity; IEA:EC.
DR   GO; GO:0006096; P:glycolysis; IEA:UniProtKB-UniPathway.
DR   Gene3D; 2.40.33.10; -; 1.
DR   Gene3D; 3.20.20.60; -; 2.
DR   Gene3D; 3.40.1380.20; -; 1.
DR   InterPro; IPR001697; Pyr_Knase.
DR   InterPro; IPR015813; Pyrv/PenolPyrv_Kinase.
DR   InterPro; IPR011037; Pyrv_Knase-like_insert_dom.
DR   InterPro; IPR015794; Pyrv_Knase_a/b.
DR   InterPro; IPR018209; Pyrv_Knase_AS.
DR   InterPro; IPR015793; Pyrv_Knase_brl.
DR   InterPro; IPR015795; Pyrv_Knase_C.
DR   InterPro; IPR015806; Pyrv_Knase_insert_dom.
DR   PANTHER; PTHR11817; PTHR11817; 1.
DR   Pfam; PF00224; PK; 1.
DR   Pfam; PF02887; PK_C; 1.
DR   PRINTS; PR01050; PYRUVTKNASE.
DR   SUPFAM; SSF50800; PK_B_barrel_like; 1.
DR   SUPFAM; SSF52935; Pyruvate_kinase; 1.
DR   SUPFAM; SSF51621; Pyrv/PenolPyrv_Kinase_cat; 1.
DR   TIGRFAMs; TIGR01064; pyruv_kin; 1.
DR   PROSITE; PS00110; PYRUVATE_KINASE; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Glycolysis; Kinase; Magnesium; Pyruvate;
KW   Transferase.
SQ   SEQUENCE   482 AA;  52489 MW;  20BCECF80BB51A2F CRC64;
     MTQPLRRTKI VTTLGPSTDK DNVLEEIIRA GANVVRMNFS HGSAEDHKTR AEKVRNIAAR
     LGRQVAILGD LQGPKIRVST FKEGKIFLSV GDLFTLDSDL PKGEGDQKSV GLDYKALPQD
     VGPEDILLLD DGRVQLQVLT VDGNKVNTRV IVGGPLSNNK GINKKGGGLS ADALTEKDKQ
     DILLAAEIKV DYLAISFPRN GADMDYARRL ARDAGLEAKL VAKVERAETV RNDENIDDII
     MASDVIMVAR GDLGVEIGDP ELIGVQKKLI KRAKELNRVV ITATQMMESM IENPMPTRAE
     VMDVANAVLD GTDAVMLSGE TAAGKYPVET VRSMAEVCIG AEKTWEPGSQ NYRIDKSFVT
     AEETIAMSTI YAANHMEGVK AMVTLTESGR TALMTSRLNS TLPIFALSPN ERTLNRCSLY
     RGVTPVFFDT KVETGFDVAM AALSTLRKKK LLDFGDLVII TQGDIMDVEG STNCMRILPV
     FD
//