ID Q7SZA7_XENLA Unreviewed; 197 AA.
AC Q7SZA7;
DT 01-OCT-2003, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2003, sequence version 1.
DT 27-MAR-2024, entry version 108.
DE RecName: Full=glutathione transferase {ECO:0000256|ARBA:ARBA00012452};
DE EC=2.5.1.18 {ECO:0000256|ARBA:ARBA00012452};
GN Name=hpgds.S {ECO:0000313|RefSeq:NP_001079730.1,
GN ECO:0000313|Xenbase:XB-GENE-944784};
GN Synonyms=gsts {ECO:0000313|RefSeq:NP_001079730.1}, hpgds
GN {ECO:0000313|RefSeq:NP_001079730.1,
GN ECO:0000313|Xenbase:XB-GENE-944784}, hpgds-a
GN {ECO:0000313|RefSeq:NP_001079730.1}, hpgds-b
GN {ECO:0000313|RefSeq:NP_001079730.1}, hpgdsb
GN {ECO:0000313|RefSeq:NP_001079730.1}, pgds
GN {ECO:0000313|RefSeq:NP_001079730.1}, XlGSTS1
GN {ECO:0000313|RefSeq:NP_001079730.1}, XlGSTS1-1
GN {ECO:0000313|EMBL:AAH53774.1}, xlgsts1-1
GN {ECO:0000313|RefSeq:NP_001079730.1};
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355 {ECO:0000313|EMBL:AAH53774.1};
RN [1] {ECO:0000313|RefSeq:NP_001079730.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=11142348; DOI=10.1080/152165400300001525;
RA Pennelli A., Ortolano S., Miele R., Renda T., Sacchetta P., Di Ilio C.,
RA Simmaco M.;
RT "Glutathione S-transferase, similar to sigma class, from skin secretions of
RT Xenopus laevis.";
RL IUBMB Life 50:203-207(2000).
RN [2] {ECO:0000313|RefSeq:NP_001079730.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=12454917; DOI=10.1002/dvdy.10174;
RA Klein S.L., Strausberg R.L., Wagner L., Pontius J., Clifton S.W.,
RA Richardson P.;
RT "Genetic and genomic tools for Xenopus research: The NIH Xenopus
RT initiative.";
RL Dev. Dyn. 225:384-391(2002).
RN [3] {ECO:0000313|RefSeq:NP_001079730.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=14592465; DOI=10.1016/j.abb.2003.08.024;
RA Carletti E., De Luca A., Urbani A., Sacchetta P., Di Ilio C.;
RT "Sigma-class glutathione transferase from Xenopus laevis: molecular
RT cloning, expression, and site-directed mutagenesis.";
RL Arch. Biochem. Biophys. 419:214-221(2003).
RN [4] {ECO:0000313|EMBL:AAH53774.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Whole {ECO:0000313|EMBL:AAH53774.1};
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases.
RN [5] {ECO:0000313|RefSeq:NP_001079730.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; BC053774; AAH53774.1; -; mRNA.
DR RefSeq; NP_001079730.1; NM_001086261.1.
DR DNASU; 379417; -.
DR GeneID; 379417; -.
DR KEGG; xla:379417; -.
DR AGR; Xenbase:XB-GENE-944784; -.
DR CTD; 379417; -.
DR Xenbase; XB-GENE-944784; hpgds.S.
DR OrthoDB; 1385810at2759; -.
DR Proteomes; UP000186698; Chromosome 1S.
DR Bgee; 379417; Expressed in camera-type eye and 19 other cell types or tissues.
DR CDD; cd10295; GST_C_Sigma; 1.
DR CDD; cd03039; GST_N_Sigma_like; 1.
DR Gene3D; 1.20.1050.10; -; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR InterPro; IPR010987; Glutathione-S-Trfase_C-like.
DR InterPro; IPR036282; Glutathione-S-Trfase_C_sf.
DR InterPro; IPR040079; Glutathione_S-Trfase.
DR InterPro; IPR004045; Glutathione_S-Trfase_N.
DR InterPro; IPR004046; GST_C.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR PANTHER; PTHR11571; GLUTATHIONE S-TRANSFERASE; 1.
DR PANTHER; PTHR11571:SF224; HEMATOPOIETIC PROSTAGLANDIN D SYNTHASE; 1.
DR Pfam; PF14497; GST_C_3; 1.
DR Pfam; PF02798; GST_N; 1.
DR SFLD; SFLDG01205; AMPS.1; 1.
DR SFLD; SFLDS00019; Glutathione_Transferase_(cytos; 1.
DR SUPFAM; SSF47616; GST C-terminal domain-like; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
DR PROSITE; PS50405; GST_CTER; 1.
DR PROSITE; PS50404; GST_NTER; 1.
PE 2: Evidence at transcript level;
KW Reference proteome {ECO:0000313|Proteomes:UP000186698}.
FT DOMAIN 2..79
FT /note="GST N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50404"
FT DOMAIN 81..194
FT /note="GST C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50405"
SQ SEQUENCE 197 AA; 22737 MW; 95FB174ADA497663 CRC64;
MPSYKLIYFN LEGRGEILRY LFSYSNIDFE DRRVEFADWP ALKPTIPYGQ LPVVEIDGVI
YNQSLAIGRY LAKKAGLTGK SELDEIRVDA LIDTIDDFFS KFPWMDTEKA KKEFMEKSSP
QLLAYLEKTL GNNPWFVGDS ATWADFFWDT CADSFESYVP GFAKDYPKLL ALKERVKAIP
TIAAWIKKRP KKIPVKH
//
