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Database: UniProt/TrEMBL
Entry: Q82M18_STRAW
LinkDB: Q82M18_STRAW
Original site: Q82M18_STRAW 
ID   Q82M18_STRAW            Unreviewed;       625 AA.
AC   Q82M18;
DT   01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT   01-JUN-2003, sequence version 1.
DT   07-JUN-2017, entry version 100.
DE   SubName: Full=Putative neuraminidase, secreted {ECO:0000313|EMBL:BAC69553.1};
GN   Name=neuA1 {ECO:0000313|EMBL:BAC69553.1};
GN   ORFNames=SAVERM_1842 {ECO:0000313|EMBL:BAC69553.1};
OS   Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 /
OS   NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680).
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Streptomyces.
OX   NCBI_TaxID=227882 {ECO:0000313|EMBL:BAC69553.1, ECO:0000313|Proteomes:UP000000428};
RN   [1] {ECO:0000313|EMBL:BAC69553.1, ECO:0000313|Proteomes:UP000000428}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 /
RC   NRRL 8165 / MA-4680 {ECO:0000313|Proteomes:UP000000428};
RX   PubMed=11572948; DOI=10.1073/pnas.211433198;
RA   Omura S., Ikeda H., Ishikawa J., Hanamoto A., Takahashi C.,
RA   Shinose M., Takahashi Y., Horikawa H., Nakazawa H., Osonoe T.,
RA   Kikuchi H., Shiba T., Sakaki Y., Hattori M.;
RT   "Genome sequence of an industrial microorganism Streptomyces
RT   avermitilis: deducing the ability of producing secondary
RT   metabolites.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:12215-12220(2001).
RN   [2] {ECO:0000313|EMBL:BAC69553.1, ECO:0000313|Proteomes:UP000000428}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 /
RC   NRRL 8165 / MA-4680 {ECO:0000313|Proteomes:UP000000428};
RX   PubMed=12692562; DOI=10.1038/nbt820;
RA   Ikeda H., Ishikawa J., Hanamoto A., Shinose M., Kikuchi H., Shiba T.,
RA   Sakaki Y., Hattori M., Omura S.;
RT   "Complete genome sequence and comparative analysis of the industrial
RT   microorganism Streptomyces avermitilis.";
RL   Nat. Biotechnol. 21:526-531(2003).
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DR   EMBL; BA000030; BAC69553.1; -; Genomic_DNA.
DR   RefSeq; WP_010983281.1; NZ_JZJK01000086.1.
DR   ProteinModelPortal; Q82M18; -.
DR   STRING; 227882.SAV_1842; -.
DR   EnsemblBacteria; BAC69553; BAC69553; SAVERM_1842.
DR   KEGG; sma:SAV_1842; -.
DR   eggNOG; ENOG4108478; Bacteria.
DR   eggNOG; COG4409; LUCA.
DR   HOGENOM; HOG000253699; -.
DR   KO; K01186; -.
DR   OMA; THGNPAP; -.
DR   OrthoDB; POG091H0EBR; -.
DR   Proteomes; UP000000428; Chromosome.
DR   GO; GO:0004308; F:exo-alpha-sialidase activity; IEA:InterPro.
DR   InterPro; IPR013320; ConA-like_dom.
DR   InterPro; IPR006558; LamG-like.
DR   InterPro; IPR001791; Laminin_G.
DR   InterPro; IPR026856; Sialidase_fam.
DR   InterPro; IPR011040; Sialidases.
DR   PANTHER; PTHR10628; PTHR10628; 1.
DR   Pfam; PF13088; BNR_2; 1.
DR   SMART; SM00282; LamG; 1.
DR   SMART; SM00560; LamGL; 1.
DR   SUPFAM; SSF49899; SSF49899; 1.
DR   SUPFAM; SSF50939; SSF50939; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000000428};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000428};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     31       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        32    625       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5004300078.
FT   DOMAIN      457    596       LamGL. {ECO:0000259|SMART:SM00560}.
FT   DOMAIN      457    591       LAM_G_DOMAIN. {ECO:0000259|SMART:
FT                                SM00282}.
SQ   SEQUENCE   625 AA;  67137 MW;  CAD6DA2F546FEAD7 CRC64;
     MPSTLRARIA STLTAVLTTA ALLALPSPAG AEQATDTGEF EQQVLFKASQ DPGYACFRIP
     AVVKTTDGTL LAFAEGRVLN CGDAADIDIV LKRSTDGGRT WGPLQVVNEG GGDTHGNPAP
     VVDRETGRIV LAETYNTGRT DSAGCTVPCD RTPHLQYSDD DGLTWSRPRD LSDEILPPEW
     NSWYATGPVH GIQLTRGRHA GRLVLGVNTE TWDGSRVSAN HAALITSDDG GDHWRIGATD
     SWPIAADGTF RQKPSEMTLA ERTDGSVLVS GREQDGTDLG HRTQAVSRDG GSSFTAPFRD
     LPDLYTPQVQ GSSLRLGDRL LLACPGDPDR RRTMTIRSSY DGGRTWDSVD RGTVVTTDWS
     GYSDLVRVGR DTVGLMYEGG AVDARDEIRF ARFTEDWLKP RRGPDPTTPD LAPHAKGAAV
     LGGAEQTEGV FGGALDFDGA DDAVRLPYRA ELPLGTKDFT ASLWFRYTAA TGEQPLLWMG
     GIGTSQPQVW LRGEPASNRV QGLITVRDGA SAPQSAFVRT TGAYNDGQWH HLALRRGGGA
     LTLFLDGTPI STADVPGSVS RNSPFGVHIG QRMDSRAYFT GSIDEVRVYG RALSDAEITG
     LRTDNEASAR DTVLRLPMDR VSGSH
//
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