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Database: UniProt/TrEMBL
Entry: Q83AH1_COXBU
LinkDB: Q83AH1_COXBU
Original site: Q83AH1_COXBU 
ID   Q83AH1_COXBU            Unreviewed;       936 AA.
AC   Q83AH1;
DT   01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT   04-NOV-2008, sequence version 2.
DT   30-AUG-2017, entry version 84.
DE   SubName: Full=Acyl-CoA synthetase {ECO:0000313|EMBL:AAO91419.2};
DE            EC=6.2.1.- {ECO:0000313|EMBL:AAO91419.2};
GN   OrderedLocusNames=CBU_1928 {ECO:0000313|EMBL:AAO91419.2};
OS   Coxiella burnetii (strain RSA 493 / Nine Mile phase I).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Legionellales;
OC   Coxiellaceae; Coxiella.
OX   NCBI_TaxID=227377 {ECO:0000313|EMBL:AAO91419.2, ECO:0000313|Proteomes:UP000002671};
RN   [1] {ECO:0000313|EMBL:AAO91419.2, ECO:0000313|Proteomes:UP000002671}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RSA 493 / Nine Mile phase I
RC   {ECO:0000313|Proteomes:UP000002671};
RX   PubMed=12704232; DOI=10.1073/pnas.0931379100;
RA   Seshadri R., Paulsen I.T., Eisen J.A., Read T.D., Nelson K.E.,
RA   Nelson W.C., Ward N.L., Tettelin H., Davidsen T.M., Beanan M.J.,
RA   Deboy R.T., Daugherty S.C., Brinkac L.M., Madupu R., Dodson R.J.,
RA   Khouri H.M., Lee K.H., Carty H.A., Scanlan D., Heinzen R.A.,
RA   Thompson H.A., Samuel J.E., Fraser C.M., Heidelberg J.F.;
RT   "Complete genome sequence of the Q-fever pathogen, Coxiella
RT   burnetii.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:5455-5460(2003).
RN   [2] {ECO:0000313|EMBL:AAO91419.2, ECO:0000313|Proteomes:UP000002671}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RSA 493 / Nine Mile phase I
RC   {ECO:0000313|Proteomes:UP000002671};
RX   PubMed=19047403; DOI=10.1128/IAI.01141-08;
RA   Beare P.A., Unsworth N., Andoh M., Voth D.E., Omsland A., Gilk S.D.,
RA   Williams K.P., Sobral B.W., Kupko J.J.III., Porcella S.F.,
RA   Samuel J.E., Heinzen R.A.;
RT   "Comparative genomics reveal extensive transposon-mediated genomic
RT   plasticity and diversity among potential effector proteins within the
RT   genus Coxiella.";
RL   Infect. Immun. 77:642-656(2009).
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00258}.
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DR   EMBL; AE016828; AAO91419.2; -; Genomic_DNA.
DR   RefSeq; NP_820905.2; NC_002971.3.
DR   RefSeq; WP_010958545.1; NC_002971.4.
DR   ProteinModelPortal; Q83AH1; -.
DR   STRING; 227377.CBU_1928; -.
DR   PRIDE; Q83AH1; -.
DR   EnsemblBacteria; AAO91419; AAO91419; CBU_1928.
DR   GeneID; 1209841; -.
DR   KEGG; cbu:CBU_1928; -.
DR   PATRIC; fig|227377.7.peg.1910; -.
DR   eggNOG; ENOG4107RCI; Bacteria.
DR   eggNOG; COG0318; LUCA.
DR   HOGENOM; HOG000026854; -.
DR   OMA; VPVDFMS; -.
DR   Proteomes; UP000002671; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0070566; F:adenylyltransferase activity; IBA:GO_Central.
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016746; F:transferase activity, transferring acyl groups; IEA:InterPro.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IBA:GO_Central.
DR   InterPro; IPR025110; AMP-bd_C.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig.
DR   InterPro; IPR002123; Plipid/glycerol_acylTrfase.
DR   InterPro; IPR009081; PP-bd_ACP.
DR   Pfam; PF01553; Acyltransferase; 1.
DR   Pfam; PF00501; AMP-binding; 1.
DR   Pfam; PF13193; AMP-binding_C; 1.
DR   Pfam; PF00550; PP-binding; 1.
DR   SMART; SM00563; PlsC; 1.
DR   SUPFAM; SSF47336; SSF47336; 1.
DR   PROSITE; PS50075; ACP_DOMAIN; 1.
DR   PROSITE; PS00455; AMP_BINDING; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000002671};
KW   Ligase {ECO:0000313|EMBL:AAO91419.2};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002671};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    697    719       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       41     83       Carrier. {ECO:0000259|PROSITE:PS50075}.
SQ   SEQUENCE   936 AA;  104786 MW;  34E5B6A7DE83D8F1 CRC64;
     MDKSLTEIES QVISLTHQFL LESGAERAAR AVSLDARLEH DLGIGSLEKA ELFSRIEKSL
     GVELPESLLV KAKQLNDVVK AVKMAEPTLL KVKREVIAPL KSTRTDPSKV ETLVELLNLY
     AQNEPDRPHI YFQNEFGEET IIRYGELYTR AKEFAQGLVG KGLKPSETVA IMLPTSADFF
     YSFLGTLMAG GIPVPIYPPF RADQIEEYAK REAFILHNAG VRFLITFKRA AALSKLLQSF
     VPSLLEVTTV KALTDISADL PTLDIEATDP VLIQYTSGST GNPKGVLLNH ANLLANISAY
     GKTLNMQSTD AFVSWLPLYH DMGLIGAWMG SFYHGLPLTL LSPFTFLSRP EKWLWAIHYH
     RGTISPGPNF AYDLCVKKIE DSDLEGLDLS SWRVALNGSE MIHPDTLRNF EKRFRKYGFK
     KEAIFPAYGL AECALGLTFP PLNRGPNIDR IERLPYEKNN TAVPLTTRDK KYYEFVSCGS
     VLEGHEIRIV DDNDNRVAER TIGNIQFKGP SAMQGYYRNS EATMAIYHNG WWATGDLGYL
     AEGELFITGR KKDLIIKAGR NYHPTEIEAM ASLAEGVRKS CVAAFGVADE KRGTEKLIIV
     AETKEDKKIQ PEIKKEIVDK VISQIGIPPD EILLVPPHTL PKTSSGKLRR SSCKQDYLAG
     KLSRPGRSAF WQTIKLFIKS RAKKIEKWLI NLIKVVFSFY VLILLFFTLL PVWLLVIILP
     RKKAAAAFRF WAGSIFRLIF SPISIKGKEN ISGQPMIYVA NHGSFIDSVI LAGVLPADTN
     FIGKKELLKT PVIKSFVKQL DLVTVDRMDF SKSHSDVKRI EQTLEQGRSV LIFPEGTFSY
     ATDVRPFKLG AFKIAAELGK PICPVAIVGA RKILRANQFL VKPAKLEVII FKPLIPESKE
     WEEVMRLRKQ SRFLIAKYSG EHVLDLVSAG VLSESE
//
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