ID   Q83ST3_SALTI            Unreviewed;       533 AA.
AC   Q83ST3;
DT   01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT   01-JUN-2003, sequence version 1.
DT   01-MAY-2013, entry version 58.
DE   RecName: Full=Malate synthase;
DE            EC=2.3.3.9;
GN   Name=aceB; OrderedLocusNames=t4111;
OS   Salmonella typhi.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=90370;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700931 / Ty2;
RX   PubMed=12644504; DOI=10.1128/JB.185.7.2330-2337.2003;
RA   Deng W., Liou S.-R., Plunkett G. III, Mayhew G.F., Rose D.J.,
RA   Burland V., Kodoyianni V., Schwartz D.C., Blattner F.R.;
RT   "Comparative genomics of Salmonella enterica serovar Typhi strains Ty2
RT   and CT18.";
RL   J. Bacteriol. 185:2330-2337(2003).
CC   -!- CATALYTIC ACTIVITY: Acetyl-CoA + H(2)O + glyoxylate = (S)-malate +
CC       CoA.
CC   -!- PATHWAY: Carbohydrate metabolism; glyoxylate cycle; (S)-malate
CC       from isocitrate: step 2/2.
CC   -!- SIMILARITY: Belongs to the malate synthase family.
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DR   EMBL; AE014613; AAO71575.1; -; Genomic_DNA.
DR   RefSeq; NP_807715.1; NC_004631.1.
DR   ProteinModelPortal; Q83ST3; -.
DR   STRING; 209261.t4111; -.
DR   EnsemblBacteria; AAO71575; AAO71575; t4111.
DR   GeneID; 1069825; -.
DR   KEGG; stt:t4111; -.
DR   PATRIC; 18558001; VBISalEnt47697_4450.
DR   HOGENOM; HOG000238464; -.
DR   KO; K01638; -.
DR   ProtClustDB; PRK09255; -.
DR   UniPathway; UPA00703; UER00720.
DR   GO; GO:0004474; F:malate synthase activity; IEA:EC.
DR   GO; GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
DR   InterPro; IPR011076; Malate_synth-like.
DR   InterPro; IPR006252; Malate_synthA.
DR   InterPro; IPR001465; Malate_synthase.
DR   InterPro; IPR019830; Malate_synthase_CS.
DR   PANTHER; PTHR21631:SF1; PTHR21631:SF1; 1.
DR   Pfam; PF01274; Malate_synthase; 1.
DR   PIRSF; PIRSF001363; Malate_synth; 1.
DR   SUPFAM; SSF51645; Malat_synth_like; 1.
DR   TIGRFAMs; TIGR01344; malate_syn_A; 1.
DR   PROSITE; PS00510; MALATE_SYNTHASE; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Glyoxylate bypass; Transferase;
KW   Tricarboxylic acid cycle.
FT   ACT_SITE    166    166       Proton acceptor (By similarity).
FT   ACT_SITE    447    447       Proton donor (By similarity).
SQ   SEQUENCE   533 AA;  60389 MW;  D48EDF04AFB9EFE1 CRC64;
     MNPQATTTDE LTFTRPQGEL EKQVLTAEAV EFLTELVTRF TPKRNKLLAA RIQQQQDIDN
     GKLPDFISET TSIRESNWQI RGIPADLQDR RVEITGPVER KMVINALNAN VKVFMADFED
     SLAPDWNKVI DGQINLRDAV NGTISYTNEA GKIYQLKPDP AVLICRVRGL HLPEKHVTWR
     GEAIPGSLFD FALYFFHNYK ALLAKGSGPY FYLPKTQAWQ EAAWWSEVFS YAEDRFNLPR
     GTIKATLLIE TLPAVFQMDE ILHALRDHIV GLNCGRWDYI FSYIKTLKNH PDRVLPDRQV
     VTMDKPFLSA YSRLLIKTCH KRGAFAMGGM AAFIPSKDVE RNNQVLAKVK ADKALEANNG
     HDGTWIAHPG LADTAMAVFN EVLGEYKNQL FITRDEDAPI TAEQLLEPCE GERTEAGMRA
     NIRVAVQYIE AWIPGNGCVP IYGLMEDAAT AEISRTSIWQ WIHHEKTLSN GKPVTKALFR
     EMLAEEMRVI QDELGEHRYS SGRFDDAARL MEQITTSDDL IDFLTLPGYR LLA
//