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Database: UniProt/TrEMBL
Entry: Q83ST3_SALTI
LinkDB: Q83ST3_SALTI
Original site: Q83ST3_SALTI 
ID   Q83ST3_SALTI            Unreviewed;       533 AA.
AC   Q83ST3; A0A0C8U301; A0A0C9FEH5;
DT   01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT   01-JUN-2003, sequence version 1.
DT   20-JAN-2016, entry version 76.
DE   RecName: Full=Malate synthase {ECO:0000256|RuleBase:RU000555};
DE            EC=2.3.3.9 {ECO:0000256|RuleBase:RU000555};
GN   Name=aceB {ECO:0000313|EMBL:CES18620.1};
GN   OrderedLocusNames=t4111 {ECO:0000313|EMBL:AAO71575.1};
GN   ORFNames=ERS083263_01442 {ECO:0000313|EMBL:CET15877.1},
GN   ERS325172_04021 {ECO:0000313|EMBL:CER24964.1}, ERS325188_03983
GN   {ECO:0000313|EMBL:CQV79535.1}, ERS325190_01784
GN   {ECO:0000313|EMBL:CQX33568.1}, ERS325196_04046
GN   {ECO:0000313|EMBL:CQT84747.1}, ERS325215_03970
GN   {ECO:0000313|EMBL:CRB72477.1}, ERS325223_03969
GN   {ECO:0000313|EMBL:CQT77696.1}, ERS325225_03954
GN   {ECO:0000313|EMBL:CQT74035.1}, ERS325232_04128
GN   {ECO:0000313|EMBL:CQT85173.1}, ERS325296_03850
GN   {ECO:0000313|EMBL:CQW06049.1}, ERS325320_03998
GN   {ECO:0000313|EMBL:CQT80475.1}, ERS325374_01837
GN   {ECO:0000313|EMBL:CQS78679.1}, ERS325434_01651
GN   {ECO:0000313|EMBL:CQW77555.1}, ERS325436_03910
GN   {ECO:0000313|EMBL:CQX84692.1}, ERS325437_01516
GN   {ECO:0000313|EMBL:CQW75953.1}, ERS326267_04038
GN   {ECO:0000313|EMBL:CES39761.1}, ERS326384_04097
GN   {ECO:0000313|EMBL:CES23820.1}, ERS326389_01724
GN   {ECO:0000313|EMBL:CES18620.1}, ERS326420_01516
GN   {ECO:0000313|EMBL:CER50414.1}, ERS326499_01888
GN   {ECO:0000313|EMBL:CRC47401.1}, ERS327392_04103
GN   {ECO:0000313|EMBL:CER76091.1};
OS   Salmonella typhi.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=90370 {ECO:0000313|EMBL:CES18620.1};
RN   [1] {ECO:0000313|EMBL:AAO71575.1, ECO:0000313|Proteomes:UP000002670}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700931 / Ty2 {ECO:0000313|Proteomes:UP000002670}, and Ty2
RC   {ECO:0000313|EMBL:AAO71575.1};
RX   PubMed=12644504; DOI=10.1128/JB.185.7.2330-2337.2003;
RA   Deng W., Liou S.-R., Plunkett G. III, Mayhew G.F., Rose D.J.,
RA   Burland V., Kodoyianni V., Schwartz D.C., Blattner F.R.;
RT   "Comparative genomics of Salmonella enterica serovar Typhi strains Ty2
RT   and CT18.";
RL   J. Bacteriol. 185:2330-2337(2003).
RN   [2] {ECO:0000313|EMBL:CES18620.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=A59307 {ECO:0000313|EMBL:CER76091.1}, Dn136
RC   {ECO:0000313|EMBL:CQT84747.1}, Dn160 {ECO:0000313|EMBL:CQT74035.1},
RC   Dn189 {ECO:0000313|EMBL:CQT85173.1}, Dn45
RC   {ECO:0000313|EMBL:CQV79535.1}, Dtc103 {ECO:0000313|EMBL:CQT77696.1},
RC   Dtc81 {ECO:0000313|EMBL:CQX33568.1}, Dtc98
RC   {ECO:0000313|EMBL:CRB72477.1}, IB5341 {ECO:0000313|EMBL:CET15877.1},
RC   MDUST167 {ECO:0000313|EMBL:CES39761.1}, MDUST284
RC   {ECO:0000313|EMBL:CES23820.1}, MDUST289 {ECO:0000313|EMBL:CES18620.1},
RC   MDUST320 {ECO:0000313|EMBL:CER50414.1}, MDUST399
RC   {ECO:0000313|EMBL:CRC47401.1}, Np93 {ECO:0000313|EMBL:CER24964.1},
RC   Ty2-101 {ECO:0000313|EMBL:CQX84692.1}, Ty2-115
RC   {ECO:0000313|EMBL:CQW75953.1}, Ty2-120 {ECO:0000313|EMBL:CQS78679.1},
RC   Ty2-170 {ECO:0000313|EMBL:CQW06049.1}, Ty2-71
RC   {ECO:0000313|EMBL:CQW77555.1}, and Ty3-193
RC   {ECO:0000313|EMBL:CQT80475.1};
RA   Informatics Pathogen;
RL   Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: Acetyl-CoA + H(2)O + glyoxylate = (S)-malate +
CC       CoA. {ECO:0000256|RuleBase:RU000555}.
CC   -!- PATHWAY: Carbohydrate metabolism; glyoxylate cycle; (S)-malate
CC       from isocitrate: step 2/2. {ECO:0000256|RuleBase:RU000555}.
CC   -!- SIMILARITY: Belongs to the malate synthase family.
CC       {ECO:0000256|RuleBase:RU000555}.
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DR   EMBL; AE014613; AAO71575.1; -; Genomic_DNA.
DR   EMBL; CEXJ01000022; CER24964.1; -; Genomic_DNA.
DR   EMBL; CEXP01000006; CER50414.1; -; Genomic_DNA.
DR   EMBL; CEXU01000023; CER76091.1; -; Genomic_DNA.
DR   EMBL; CEYF01000006; CES18620.1; -; Genomic_DNA.
DR   EMBL; CEYE01000023; CES23820.1; -; Genomic_DNA.
DR   EMBL; CEYH01000023; CES39761.1; -; Genomic_DNA.
DR   EMBL; CEZA01000005; CET15877.1; -; Genomic_DNA.
DR   EMBL; CUYZ01000006; CQS78679.1; -; Genomic_DNA.
DR   EMBL; CUYJ01000023; CQT74035.1; -; Genomic_DNA.
DR   EMBL; CUZV01000021; CQT77696.1; -; Genomic_DNA.
DR   EMBL; CUZW01000022; CQT80475.1; -; Genomic_DNA.
DR   EMBL; CUYV01000024; CQT84747.1; -; Genomic_DNA.
DR   EMBL; CUYW01000023; CQT85173.1; -; Genomic_DNA.
DR   EMBL; CVAI01000021; CQV79535.1; -; Genomic_DNA.
DR   EMBL; CVBK01000021; CQW06049.1; -; Genomic_DNA.
DR   EMBL; CVCL01000006; CQW75953.1; -; Genomic_DNA.
DR   EMBL; CVCJ01000006; CQW77555.1; -; Genomic_DNA.
DR   EMBL; CVCV01000006; CQX33568.1; -; Genomic_DNA.
DR   EMBL; CVCK01000021; CQX84692.1; -; Genomic_DNA.
DR   EMBL; CVFY01000022; CRB72477.1; -; Genomic_DNA.
DR   EMBL; CVGS01000006; CRC47401.1; -; Genomic_DNA.
DR   RefSeq; WP_001069374.1; NZ_CXZB01000006.1.
DR   STRING; 220341.STY4401; -.
DR   EnsemblBacteria; CEQ58876; CEQ58876; ERS326331_01855.
DR   EnsemblBacteria; CER12541; CER12541; ERS248971_01711.
DR   EnsemblBacteria; CER18175; CER18175; ERS326259_01648.
DR   EnsemblBacteria; CER24964; CER24964; ERS325172_04021.
DR   EnsemblBacteria; CER32393; CER32393; ERS326407_03980.
DR   EnsemblBacteria; CER45945; CER45945; ERS326268_01856.
DR   EnsemblBacteria; CER50414; CER50414; ERS326420_01516.
DR   EnsemblBacteria; CER62240; CER62240; ERS326373_01684.
DR   EnsemblBacteria; CER62972; CER62972; ERS326475_01854.
DR   EnsemblBacteria; CER68746; CER68746; ERS325101_03965.
DR   EnsemblBacteria; CES10051; CES10051; ERS326256_01860.
DR   EnsemblBacteria; CES18620; CES18620; ERS326389_01724.
DR   EnsemblBacteria; CES23820; CES23820; ERS326384_04097.
DR   EnsemblBacteria; CES39761; CES39761; ERS326267_04038.
DR   EnsemblBacteria; CET15877; CET15877; ERS083263_01442.
DR   EnsemblBacteria; CET24385; CET24385; ERS326469_01605.
DR   EnsemblBacteria; CET75854; CET75854; ERS326314_01857.
DR   EnsemblBacteria; CET87093; CET87093; ERS326275_01645.
DR   EnsemblBacteria; CEU05875; CEU05875; ERS326412_04074.
DR   KEGG; stt:t4111; -.
DR   eggNOG; COG2225; LUCA.
DR   eggNOG; ENOG4107QP3; Bacteria.
DR   KO; K01638; -.
DR   UniPathway; UPA00703; UER00720.
DR   Proteomes; UP000002670; Chromosome.
DR   GO; GO:0004474; F:malate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
DR   InterPro; IPR011076; Malate_synth-like.
DR   InterPro; IPR006252; Malate_synthA.
DR   InterPro; IPR001465; Malate_synthase.
DR   InterPro; IPR019830; Malate_synthase_CS.
DR   Pfam; PF01274; Malate_synthase; 1.
DR   PIRSF; PIRSF001363; Malate_synth; 1.
DR   SUPFAM; SSF51645; SSF51645; 1.
DR   TIGRFAMs; TIGR01344; malate_syn_A; 1.
DR   PROSITE; PS00510; MALATE_SYNTHASE; 1.
PE   3: Inferred from homology;
KW   Acyltransferase {ECO:0000313|EMBL:CES18620.1};
KW   Complete proteome {ECO:0000313|Proteomes:UP000002670};
KW   Glyoxylate bypass {ECO:0000256|RuleBase:RU000555};
KW   Transferase {ECO:0000256|RuleBase:RU000555,
KW   ECO:0000313|EMBL:CES18620.1};
KW   Tricarboxylic acid cycle {ECO:0000256|RuleBase:RU000555}.
FT   ACT_SITE    166    166       Proton acceptor. {ECO:0000256|PIRSR:
FT                                PIRSR001363-1}.
FT   ACT_SITE    447    447       Proton donor. {ECO:0000256|PIRSR:
FT                                PIRSR001363-1}.
SQ   SEQUENCE   533 AA;  60389 MW;  D48EDF04AFB9EFE1 CRC64;
     MNPQATTTDE LTFTRPQGEL EKQVLTAEAV EFLTELVTRF TPKRNKLLAA RIQQQQDIDN
     GKLPDFISET TSIRESNWQI RGIPADLQDR RVEITGPVER KMVINALNAN VKVFMADFED
     SLAPDWNKVI DGQINLRDAV NGTISYTNEA GKIYQLKPDP AVLICRVRGL HLPEKHVTWR
     GEAIPGSLFD FALYFFHNYK ALLAKGSGPY FYLPKTQAWQ EAAWWSEVFS YAEDRFNLPR
     GTIKATLLIE TLPAVFQMDE ILHALRDHIV GLNCGRWDYI FSYIKTLKNH PDRVLPDRQV
     VTMDKPFLSA YSRLLIKTCH KRGAFAMGGM AAFIPSKDVE RNNQVLAKVK ADKALEANNG
     HDGTWIAHPG LADTAMAVFN EVLGEYKNQL FITRDEDAPI TAEQLLEPCE GERTEAGMRA
     NIRVAVQYIE AWIPGNGCVP IYGLMEDAAT AEISRTSIWQ WIHHEKTLSN GKPVTKALFR
     EMLAEEMRVI QDELGEHRYS SGRFDDAARL MEQITTSDDL IDFLTLPGYR LLA
//
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