ID   Q8YGV0_BRUME            Unreviewed;       891 AA.
AC   Q8YGV0; D0B2X3;
DT   01-MAR-2002, integrated into UniProtKB/TrEMBL.
DT   01-MAR-2002, sequence version 1.
DT   01-MAY-2013, entry version 70.
DE   SubName: Full=Ribonuclease E and G;
DE   SubName: Full=Ribonuclease e / zinc metalloprotease;
DE            EC=3.1.4.-;
DE            EC=3.4.24.-;
GN   OrderedLocusNames=BMEI1057; ORFNames=BAWG_1153;
OS   Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Brucellaceae; Brucella.
OX   NCBI_TaxID=224914;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=16M / ATCC 23456 / NCTC 10094;
RX   PubMed=11756688; DOI=10.1073/pnas.221575398;
RA   DelVecchio V.G., Kapatral V., Redkar R.J., Patra G., Mujer C., Los T.,
RA   Ivanova N., Anderson I., Bhattacharyya A., Lykidis A., Reznik G.,
RA   Jablonski L., Larsen N., D'Souza M., Bernal A., Mazur M., Goltsman E.,
RA   Selkov E., Elzer P.H., Hagius S., O'Callaghan D., Letesson J.-J.,
RA   Haselkorn R., Kyrpides N.C., Overbeek R.;
RT   "The genome sequence of the facultative intracellular pathogen
RT   Brucella melitensis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:443-448(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=16M;
RG   The Broad Institute Genome Sequencing Platform;
RA   Ward D., Young S.K., Kodira C.D., Zeng Q., Koehrsen M., Alvarado L.,
RA   Berlin A., Borenstein D., Chen Z., Engels R., Freedman E.,
RA   Gellesch M., Goldberg J., Griggs A., Gujja S., Heiman D., Hepburn T.,
RA   Howarth C., Jen D., Larson L., Lewis B., Mehta T., Park D.,
RA   Pearson M., Roberts A., Saif S., Shea T., Shenoy N., Sisk P.,
RA   Stolte C., Sykes S., Walk T., White J., Yandava C., Whatmore A.M.,
RA   Perrett L.L., O'Callaghan D., Nusbaum C., Galagan J., Birren B.;
RT   "The Genome Sequence of Brucella melitensis bv. 1 str. 16M.";
RL   Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; AE008917; AAL52238.1; -; Genomic_DNA.
DR   EMBL; GG703778; EEW89045.1; -; Genomic_DNA.
DR   PIR; AC3384; AC3384.
DR   RefSeq; NP_539974.1; NC_003317.1.
DR   STRING; 224914.BMEI1057; -.
DR   EnsemblBacteria; AAL52238; AAL52238; BMEI1057.
DR   EnsemblBacteria; EEW89045; EEW89045; BAWG_1153.
DR   GeneID; 1196768; -.
DR   KEGG; bme:BMEI1057; -.
DR   PATRIC; 17797932; VBIBruMel146950_0781.
DR   eggNOG; COG1530; -.
DR   HOGENOM; HOG000258026; -.
DR   KO; K08300; -.
DR   OMA; MGIILRT; -.
DR   ProtClustDB; CLSK898310; -.
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0004540; F:ribonuclease activity; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR   Gene3D; 2.40.50.140; -; 2.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   InterPro; IPR003029; Rbsml_prot_S1_RNA-bd_dom.
DR   InterPro; IPR019307; RNA-bd_AU-1/RNase_E/G.
DR   InterPro; IPR022967; RNA-binding_domain_S1.
DR   InterPro; IPR004659; RNase_E/G.
DR   InterPro; IPR001878; Znf_CCHC.
DR   Pfam; PF10150; RNase_E_G; 1.
DR   Pfam; PF00575; S1; 1.
DR   SMART; SM00316; S1; 1.
DR   SMART; SM00343; ZnF_C2HC; 1.
DR   SUPFAM; SSF50249; Nucleic_acid_OB; 1.
DR   TIGRFAMs; TIGR00757; RNaseEG; 1.
PE   4: Predicted;
KW   Complete proteome; Hydrolase; Metalloprotease; Protease.
SQ   SEQUENCE   891 AA;  100323 MW;  B76EEDDFC870C0CC CRC64;
     MSNKMLIDAS HPEETRVIVT RGNKIEEFDF ESEHKKQLKG NIYLARVTRV EPSLQAAFVE
     YGGNRHGFLA FSEIHPDYYQ IPVADRLALL EAEAKAARAE DDEDEPRAKS DRSERNDRAR
     RNRRRGGRRD GQNGEAQANG ADKDLPAAEP VGPGFADYVA GTPAAALTQK GDIISEALDN
     GDDDDVENEE DMVESVGSED ALEELPTHTR THRRQYNIQE VIKRRQILLV QVVKEERGNK
     GAALTTYLSL AGRYSVLMPN TARGGGISRK ITNPQDRKRL KEIVKELEVP QGMGVILRTA
     GANRTKAEVK RDYEYLMRLW ENVRTLTLQS TAPALVYEEG SLIKRSIRDI YNKDITEILV
     SGENGYREAK DFMRMLMPSH AKVVQPYRDH IPIFTRNGVE AQLDRMLVPQ VTLKSGGYLI
     INQTEALVAI DVNSGRSTRE HSIEDTALQT NLEAAEEVAR QLRLRDLAGL IVVDFIDMEE
     KRNNRAVEKK MKECLKDDRA RIQVGRISHF GLLEMSRQRI RASVLESTMQ VCPHCGGTGH
     IRSDSSMALH IIRGIEDYLL RHSGFDIHVR TPAASALYVL NHKRQILADL EGRFGVEISI
     DADESVGNQH FVIDKGAPST RPVTPSAVQP MVYEDDIEDP EIPVEEDETE EEARTDVQAG
     EERSEENDRK RRRRRRRRGG RERDGRDLSA QEEAVSEEAS EEDNETDQAN EAVSSASMSE
     EDRRKKRRRG RRGGRKNRRE DDNRARRIPD PEFVGYTPVL PVKAEESIGE VVETVETVEA
     PVVEAAPEEK PEKPARKTRT RKKAVDEAPA DEAAAPAEEV VPEKPKRRTR KAAAKPVVEA
     EDVAEVKETV AAETQVETIA EPKSTEPVVT SSESEDRKPK RSGWWQKKGF F
//