ID Q95YD8_CAEEL Unreviewed; 373 AA.
AC Q95YD8;
DT 01-DEC-2001, integrated into UniProtKB/TrEMBL.
DT 01-DEC-2001, sequence version 1.
DT 01-MAY-2013, entry version 81.
DE SubName: Full=Protein IDHG-2;
GN Name=idhg-2; ORFNames=C30F12.7, CELE_C30F12.7;
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG Caenorhabditis elegans Sequencing Consortium;
RT "Genome sequence of the nematode C. elegans: a platform for
RT investigating biology.";
RL Science 282:2012-2018(1998).
CC -!- SIMILARITY: Belongs to the isocitrate and isopropylmalate
CC dehydrogenases family.
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DR EMBL; FO080730; CCD66235.1; -; Genomic_DNA.
DR RefSeq; NP_491989.1; NM_059588.6.
DR HSSP; P08200; 1ISO.
DR ProteinModelPortal; Q95YD8; -.
DR SMR; Q95YD8; 31-366.
DR STRING; 6239.C30F12.7; -.
DR STRING; Q95YD8; -.
DR PaxDb; Q95YD8; -.
DR EnsemblMetazoa; C30F12.7; C30F12.7; C30F12.7.
DR GeneID; 172430; -.
DR KEGG; cel:CELE_C30F12.7; -.
DR UCSC; C30F12.7; c. elegans.
DR CTD; 172430; -.
DR WormBase; C30F12.7; CE16887; WBGene00016266; idhg-2.
DR eggNOG; COG0473; -.
DR GeneTree; ENSGT00590000083091; -.
DR HOGENOM; HOG000021113; -.
DR InParanoid; Q95YD8; -.
DR KO; K00030; -.
DR OMA; SGSERIC; -.
DR NextBio; 875479; -.
DR GO; GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:InterPro.
DR GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
DR Gene3D; 3.40.718.10; -; 1.
DR InterPro; IPR019818; IsoCit/isopropylmalate_DH_CS.
DR InterPro; IPR001804; Isocitrate/isopropylmalate_DH.
DR InterPro; IPR004434; Isocitrate_DH_NAD.
DR InterPro; IPR024084; IsoPropMal-DH-like_dom.
DR PANTHER; PTHR11835; PTHR11835; 1.
DR Pfam; PF00180; Iso_dh; 1.
DR TIGRFAMs; TIGR00175; mito_nad_idh; 1.
DR PROSITE; PS00470; IDH_IMDH; 1.
PE 3: Inferred from homology;
KW Complete proteome; Oxidoreductase; Reference proteome.
SQ SEQUENCE 373 AA; 40850 MW; 9572BD21EADE2B3C CRC64;
MFSKLPIQAV RGAASAIRTH QIPGHRLPLA KYGGRHTVCA LPGDGIGPEM IAHIRNIFSF
CHAPVNFEEV QVSSSLLDGD MDAAMLAIER NGVAIKGNIE TKHDDPQFNS RNVELRTKLD
LYANILHCVT IPTVPTRHSG IDIVLIRENT EGEYSGLEHE AVPGIVESIK IVTREKIERI
SRMAFEYAKA NGRKKVTAVH KANIQKLGDG LFLKVVRDMS EDYKDIKFEA MIVDNASMQL
VSKPQQFDVM VMPNLYGNII SNIACGLVGG PGLVSGMNLG DKYAVFETGT RNTGTSLAGK
DIANPTAFIR ASVDMLRYLG CHYHANIISD ALWKALVEQR IHTADIGGNN SASDVINATL
QNIKVLMDEN PKH
//
