ID Q99ZX8_STRP1 Unreviewed; 322 AA.
AC Q99ZX8; Q48Z49;
DT 01-JUN-2001, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2001, sequence version 1.
DT 01-MAY-2013, entry version 73.
DE SubName: Full=Putative acetoin dehydrogenase (TPP-dependent) alpha chain;
DE SubName: Full=Pyruvate dehydrogenase E1 component alpha subunit;
DE EC=1.2.4.1;
GN Name=acoA; OrderedLocusNames=M5005_Spy0751, SPy_1026;
OS Streptococcus pyogenes serotype M1.
OC Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=301447;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700294 / SF370 / Serotype M1;
RX PubMed=11296296; DOI=10.1073/pnas.071559398;
RA Ferretti J.J., McShan W.M., Ajdic D.J., Savic D.J., Savic G., Lyon K.,
RA Primeaux C., Sezate S., Suvorov A.N., Kenton S., Lai H.S., Lin S.P.,
RA Qian Y., Jia H.G., Najar F.Z., Ren Q., Zhu H., Song L., White J.,
RA Yuan X., Clifton S.W., Roe B.A., McLaughlin R.E.;
RT "Complete genome sequence of an M1 strain of Streptococcus pyogenes.";
RL Proc. Natl. Acad. Sci. U.S.A. 98:4658-4663(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-947 / MGAS5005 / Serotype M1;
RX PubMed=16088826; DOI=10.1086/432514;
RA Sumby P., Porcella S.F., Madrigal A.G., Barbian K.D., Virtaneva K.,
RA Ricklefs S.M., Sturdevant D.E., Graham M.R., Vuopio-Varkila J.,
RA Hoe N.P., Musser J.M.;
RT "Evolutionary origin and emergence of a highly successful clone of
RT serotype M1 group A Streptococcus involved multiple horizontal gene
RT transfer events.";
RL J. Infect. Dis. 192:771-782(2005).
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DR EMBL; AE004092; AAK33920.1; -; Genomic_DNA.
DR EMBL; CP000017; AAZ51369.1; -; Genomic_DNA.
DR RefSeq; NP_269199.1; NC_002737.1.
DR RefSeq; YP_282114.1; NC_007297.1.
DR HSSP; P08559; 1NI4.
DR EnsemblBacteria; AAK33920; AAK33920; SPy_1026.
DR EnsemblBacteria; AAZ51369; AAZ51369; M5005_Spy0751.
DR GeneID; 3572155; -.
DR GeneID; 901160; -.
DR KEGG; spy:SPy_1026; -.
DR KEGG; spz:M5005_Spy_0751; -.
DR PATRIC; 19715639; VBIStrPyo79812_0884.
DR HOGENOM; HOG000281336; -.
DR KO; K00161; -.
DR OMA; HLTYDDI; -.
DR ProtClustDB; CLSK877146; -.
DR GO; GO:0004739; F:pyruvate dehydrogenase (acetyl-transferring) activity; IEA:EC.
DR InterPro; IPR001017; DH_E1.
DR Pfam; PF00676; E1_dh; 1.
PE 4: Predicted;
KW Complete proteome; Oxidoreductase; Pyruvate.
SQ SEQUENCE 322 AA; 35445 MW; E884B46D80CE0EBF CRC64;
MVTVSKEQHL DMFLKMERIR EFDSRINKLV RRGFVQGMTH FSVGEEAANV GAVAHLSYDD
IIFSNHRGHG QSIAKDMDLN KMMAELAGKA TGVSKGRGGS MHLADFEKGN YGTNGIVGGG
YALAVGAALT QQYKGTNNIA VAFSGDGATN EGSFHESVNM AATWKLPVIF FIINNRYGIS
MSINNATNTP HLYTRAEAYG VPGFYCEDGN DVMAVYETMG KAVEHVRGGN GPAIVEVESY
RWFGHSTADA GKYRTKEEVD EWKEKDPMIK YRTYLTSEGI ATDDELDAIQ AQVKKEVDDA
YEFAQNSPDP ELSVAFEDVW VD
//
