ID   Q9I1K5_PSEAE            Unreviewed;       356 AA.
AC   Q9I1K5;
DT   01-MAR-2001, integrated into UniProtKB/TrEMBL.
DT   01-MAR-2001, sequence version 1.
DT   01-MAY-2013, entry version 67.
DE   SubName: Full=Putative uncharacterized protein;
GN   OrderedLocusNames=PA2268;
OS   Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG
OS   12228).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=208964;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228;
RX   PubMed=10984043; DOI=10.1038/35023079;
RA   Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P.,
RA   Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M.,
RA   Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y.,
RA   Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R.M.,
RA   Smith K.A., Spencer D.H., Wong G.K.-S., Wu Z., Paulsen I.T.,
RA   Reizer J., Saier M.H. Jr., Hancock R.E.W., Lory S., Olson M.V.;
RT   "Complete genome sequence of Pseudomonas aeruginosa PAO1, an
RT   opportunistic pathogen.";
RL   Nature 406:959-964(2000).
CC   -!- FUNCTION: Catalyzes the ATP-dependent amination of UTP to CTP with
CC       either L-glutamine or ammonia as the source of nitrogen (By
CC       similarity).
CC   -!- CATALYTIC ACTIVITY: ATP + UTP + NH(3) = ADP + phosphate + CTP.
CC   -!- PATHWAY: Pyrimidine metabolism; CTP biosynthesis via de novo
CC       pathway; CTP from UDP: step 2/2.
CC   -!- SIMILARITY: Contains 1 glutamine amidotransferase type-1 domain.
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DR   EMBL; AE004091; AAG05656.1; -; Genomic_DNA.
DR   PIR; C83363; C83363.
DR   RefSeq; NP_250958.1; NC_002516.2.
DR   ProteinModelPortal; Q9I1K5; -.
DR   SMR; Q9I1K5; 5-232, 247-343.
DR   STRING; 208964.PA2268; -.
DR   GeneID; 878537; -.
DR   KEGG; pae:PA2268; -.
DR   PATRIC; 19838981; VBIPseAer58763_2370.
DR   PseudoCAP; PA2268; -.
DR   HOGENOM; HOG000286849; -.
DR   KO; K07145; -.
DR   OMA; PFLGTCG; -.
DR   UniPathway; UPA00159; UER00277.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003883; F:CTP synthase activity; IEA:InterPro.
DR   GO; GO:0044210; P:'de novo' CTP biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.
DR   InterPro; IPR007138; Antibiotic_mOase.
DR   InterPro; IPR004468; CTP_synthase.
DR   InterPro; IPR011008; Dimeric_a/b-barrel.
DR   InterPro; IPR017926; GATASE_1.
DR   PANTHER; PTHR11550; PTHR11550; 1.
DR   Pfam; PF03992; ABM; 1.
DR   Pfam; PF00117; GATase; 1.
DR   SUPFAM; SSF54909; Dimer_A_B_barrel; 1.
DR   PROSITE; PS51273; GATASE_TYPE_1; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Glutamine amidotransferase; Ligase;
KW   Nucleotide-binding; Pyrimidine biosynthesis; Reference proteome.
SQ   SEQUENCE   356 AA;  39109 MW;  A1D6D04ACCF16FF0 CRC64;
     MSTPPAAPLR IALVGDHDPH ITAHRAIPLA LRLAGEALGL EIAFDWLASD RLPAEPALER
     YDGFWCVPGS PYRDADAVLR LIAHARGRRR PFLGTCAGFQ HTILEFARNA LGWQAATHGE
     EHPHSDQAVI AALPCALLEA REDVRLLRGS RLALAYAADW IEADYHCRYA IAPRFAAELT
     GGALRASAWS ADGAIRAVEL EQHPFFVATL FQPERAALAG VLPPLPKAFV EACRTQRRDH
     PRRGPTPYYA VIFSSHRSAV DDGYAEAAER MLELASRQPG YLGVESVRGA NGFGITVSYW
     DSEAAIRAWS RHAEHRDAQA RGRHDWYAGF SARIARVERE YAFPAQPDTA QSPASS
//