ID Q9V0G5_PYRAB Unreviewed; 398 AA.
AC Q9V0G5;
DT 01-MAY-2000, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2000, sequence version 1.
DT 27-MAR-2024, entry version 123.
DE SubName: Full=Alanine aminotransferase {ECO:0000313|EMBL:CAB49738.1, ECO:0000313|EMBL:CCE70226.1};
GN Name=aspB-like2 {ECO:0000313|EMBL:CCE70226.1};
GN ORFNames=PAB1810 {ECO:0000313|EMBL:CAB49738.1};
OS Pyrococcus abyssi (strain GE5 / Orsay).
OC Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC Pyrococcus.
OX NCBI_TaxID=272844 {ECO:0000313|EMBL:CAB49738.1, ECO:0000313|Proteomes:UP000000810};
RN [1] {ECO:0000313|EMBL:CAB49738.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Orsay {ECO:0000313|EMBL:CAB49738.1};
RA Genoscope;
RL Submitted (JUL-1999) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CAB49738.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Orsay {ECO:0000313|EMBL:CAB49738.1};
RX PubMed=10736225; DOI=10.1006/jmbi.2000.3593;
RA Gaspin C., Cavaille J., Erauso G.;
RT "Archaeal homologs of eukaryotic methylation guide small nucleolar RNAs:
RT lessons from the Pyrococcus genomes.";
RL J. Mol. Biol. 297:895-906(2000).
RN [3] {ECO:0000313|EMBL:CAB49738.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Orsay {ECO:0000313|EMBL:CAB49738.1};
RX PubMed=11381026; DOI=10.1101/gr.GR1653R;
RA Lecompte O., Ripp R., Puzos-Barbe V., Duprat S., Heilig R., Dietrich J.,
RA Thierry J.C., Poch O.;
RT "Genome evolution at the genus level: comparison of three complete genomes
RT of hyperthermophilic archaea.";
RL Genome Res. 11:981-993(2001).
RN [4] {ECO:0000313|EMBL:CAB49738.1, ECO:0000313|Proteomes:UP000000810}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GE5 / Orsay {ECO:0000313|Proteomes:UP000000810}, and Orsay
RC {ECO:0000313|EMBL:CAB49738.1};
RX PubMed=12622808; DOI=10.1046/j.1365-2958.2003.03381.x;
RA Cohen G., Barbe V., Flament D., Galperin M., Heilig R., Ripp R.,
RA Lecompte O., Prieur D., Poch O., Quellerou J., Thierry J.C.,
RA Van der Oost J., Weissenbach J., Zivanovic Y., Forterre P.;
RT "An integrated analysis of the genome of the hyperthermophilic archaeon
RT Pyrococcus abyssi.";
RL Mol. Microbiol. 47:1495-1512(2003).
RN [5] {ECO:0000313|EMBL:CCE70226.1, ECO:0000313|Proteomes:UP000009139}
RP GENOME REANNOTATION.
RC STRAIN=GE5 {ECO:0000313|EMBL:CCE70226.1}, and GE5 / Orsay
RC {ECO:0000313|Proteomes:UP000009139};
RX PubMed=22057919; DOI=10.1007/s00284-011-0035-x;
RA Gao J., Wang J.;
RT "Re-annotation of two hyperthermophilic archaea Pyrococcus abyssi GE5 and
RT Pyrococcus furiosus DSM 3638.";
RL Curr. Microbiol. 64:118-129(2012).
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
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DR EMBL; AJ248285; CAB49738.1; -; Genomic_DNA.
DR EMBL; HE613800; CCE70226.1; -; Genomic_DNA.
DR PIR; A75128; A75128.
DR RefSeq; WP_010867946.1; NC_000868.1.
DR AlphaFoldDB; Q9V0G5; -.
DR SMR; Q9V0G5; -.
DR STRING; 272844.PAB1810; -.
DR GeneID; 1496170; -.
DR KEGG; pab:PAB1810; -.
DR PATRIC; fig|272844.11.peg.870; -.
DR eggNOG; arCOG01131; Archaea.
DR HOGENOM; CLU_017584_4_3_2; -.
DR OrthoDB; 372018at2157; -.
DR Proteomes; UP000000810; Chromosome.
DR Proteomes; UP000009139; Chromosome.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0008483; F:transaminase activity; IEA:UniProtKB-KW.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR CDD; cd00609; AAT_like; 1.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR004839; Aminotransferase_I/II.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR PANTHER; PTHR43488; GLUTAMATE-PYRUVATE AMINOTRANSFERASE ALAA; 1.
DR PANTHER; PTHR43488:SF2; GLUTAMATE-PYRUVATE AMINOTRANSFERASE ALAA; 1.
DR Pfam; PF00155; Aminotran_1_2; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE 4: Predicted;
KW Aminotransferase {ECO:0000313|EMBL:CAB49738.1};
KW Transferase {ECO:0000313|EMBL:CCE70226.1}.
FT DOMAIN 31..387
FT /note="Aminotransferase class I/classII"
FT /evidence="ECO:0000259|Pfam:PF00155"
SQ SEQUENCE 398 AA; 45276 MW; 5F89690A5D135AE6 CRC64;
MVRASKRALS IEYAIRDVVL PARELEKKGI KVIRLNIGDP VKFDFQPPEH MKEAYCKAIK
EGHNYYGDSE GLMELREAIV EREKKKNGVN ITPDDVRVTA AVTEALQMIF GALLDPGDEI
LIPGPSYPPY TGLVKFYGGV PVEYRTIEEE GWQPDIDDLR KKITERTKAI AVINPNNPTG
ALYDKKTLEE IINIAGEHDI PVLSDEIYDL MTYEGKHISP ASLTKDVPVI VMNGLSKVYF
ATGWRLGYMY FVDPEGKLSE VREAIDKLAR IRLCPNTPAQ FAAIAGLRGP MDYLEEYMKK
LKERRDYIYK RLNEIPGIST TKPQGAFYIF PRIEEGPWKD DKEFVLDVLH NAHVLFVHGS
GFGEYGRGHF RAVFLPPVEV LEEAMNRFEK FMREKLSS
//
