ID R7QCM5_CHOCR Unreviewed; 5121 AA.
AC R7QCM5;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=ZZ-type domain-containing protein {ECO:0000259|PROSITE:PS50135};
GN ORFNames=CHC_T00004279001 {ECO:0000313|EMBL:CDF35829.1};
OS Chondrus crispus (Carrageen Irish moss) (Polymorpha crispa).
OC Eukaryota; Rhodophyta; Florideophyceae; Rhodymeniophycidae; Gigartinales;
OC Gigartinaceae; Chondrus.
OX NCBI_TaxID=2769 {ECO:0000313|EMBL:CDF35829.1, ECO:0000313|Proteomes:UP000012073};
RN [1] {ECO:0000313|Proteomes:UP000012073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Stackhouse {ECO:0000313|Proteomes:UP000012073};
RX PubMed=23503846; DOI=10.1073/pnas.1221259110;
RA Collen J., Porcel B., Carre W., Ball S.G., Chaparro C., Tonon T.,
RA Barbeyron T., Michel G., Noel B., Valentin K., Elias M., Artiguenave F.,
RA Arun A., Aury J.M., Barbosa-Neto J.F., Bothwell J.H., Bouget F.Y.,
RA Brillet L., Cabello-Hurtado F., Capella-Gutierrez S., Charrier B.,
RA Cladiere L., Cock J.M., Coelho S.M., Colleoni C., Czjzek M., Da Silva C.,
RA Delage L., Denoeud F., Deschamps P., Dittami S.M., Gabaldon T.,
RA Gachon C.M., Groisillier A., Herve C., Jabbari K., Katinka M., Kloareg B.,
RA Kowalczyk N., Labadie K., Leblanc C., Lopez P.J., McLachlan D.H.,
RA Meslet-Cladiere L., Moustafa A., Nehr Z., Nyvall Collen P., Panaud O.,
RA Partensky F., Poulain J., Rensing S.A., Rousvoal S., Samson G.,
RA Symeonidi A., Weissenbach J., Zambounis A., Wincker P., Boyen C.;
RT "Genome structure and metabolic features in the red seaweed Chondrus
RT crispus shed light on evolution of the Archaeplastida.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:5247-5252(2013).
CC -!- SIMILARITY: Belongs to the UBR4 family.
CC {ECO:0000256|ARBA:ARBA00009970}.
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DR EMBL; HG001749; CDF35829.1; -; Genomic_DNA.
DR RefSeq; XP_005715648.1; XM_005715591.1.
DR STRING; 2769.R7QCM5; -.
DR EnsemblPlants; CDF35829; CDF35829; CHC_T00004279001.
DR GeneID; 17323361; -.
DR Gramene; CDF35829; CDF35829; CHC_T00004279001.
DR KEGG; ccp:CHC_T00004279001; -.
DR OMA; VHRMEEH; -.
DR OrthoDB; 10597at2759; -.
DR PhylomeDB; R7QCM5; -.
DR Proteomes; UP000012073; Unassembled WGS sequence.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd19674; UBR-box_UBR4_like; 1.
DR CDD; cd02249; ZZ; 1.
DR Gene3D; 3.30.60.90; -; 1.
DR InterPro; IPR025704; E3_Ub_ligase_UBR4_C.
DR InterPro; IPR045189; UBR4-like.
DR InterPro; IPR003126; Znf_UBR.
DR InterPro; IPR000433; Znf_ZZ.
DR InterPro; IPR043145; Znf_ZZ_sf.
DR PANTHER; PTHR21725; E3 UBIQUITIN-PROTEIN LIGASE UBR4; 1.
DR Pfam; PF13764; E3_UbLigase_R4; 1.
DR SMART; SM00396; ZnF_UBR1; 1.
DR SMART; SM00291; ZnF_ZZ; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50135; ZF_ZZ_2; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000012073};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00228}.
FT DOMAIN 2368..2425
FT /note="ZZ-type"
FT /evidence="ECO:0000259|PROSITE:PS50135"
FT REGION 91..116
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 183..221
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1110..1155
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1229..1252
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1274..1293
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2342..2364
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2846..2865
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3158..3193
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3364..3406
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3664..3730
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3762..3800
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3840..3862
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4237..4256
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4746..4765
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 99..116
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 200..217
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1111..1130
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2346..2364
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3381..3406
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3762..3776
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3782..3797
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4749..4765
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 5121 AA; 561790 MW; 6B4E19D9E1E54FD0 CRC64;
MHLGTIVIEH PGIEPMGWIH VANRIVMSSS TSISRRTSVL SALFGGMIKA ANRYEASERD
LKAAEAAVCL LSTLHVVLET DMARDSQAEY GPMRGKVQQR TQPGVSKASS GDTTGTTAIS
HAARSFLGER VVAAEEDGDE GRIAARTVYQ ACEEYAERAG EPDGMMGLLA RLFASAARHY
HSESTDESVV SISEGTLPGH PEESDTSSDS PNVRSESPPF TLDVFDQRSK DGCAASATIG
SNSEAGADPT ERVELHREVA ALSLDTLAHW VSRADSLGSR EGLDMREFVV NICKSASFFS
LRNSPASYDL HAAMVDFGSL VGPLIFQQTN NSQADDKPEG RAALVFTLIT ACQKMNPILK
RVLSFDRGVS VVRTLAKALL EKVEEDRPVP DQSSEASHGL PVDDLVSAIM TLLSAENAVD
VVEILCQYIK APRKVETANV TIAHRAACLI VLSRAINVTL GILDDRDATR VAIAALYNRD
VDHALDPVFP HLVAELVPEA ISDSQQSPIW EPDDRLLASL HGITKSVDRM CFHPSFGSWG
GLSDLATLPT ESVVQCSEVS SQSTVSAKLC FHLFWGSVML HRALASVAKV TSFTFTGLCP
LSDEPASFPL SSPFVCMNAT ESKVGNDRLR ERLDHRQKSS IPLLYTAECL AFLHPQTGMR
SDEQKVFADH DLLSLISSLV KNIVDIVSDH VCPDEGSTFK ALHRAFRKDF VFDSEDRVEE
ETELRRQIRP AMTRDQTSYA CLQLAMAYMR DIGSNQIAQL LGTVMVSVSH FLARLNPQQL
EEARDLMVDV SKLLLFLPDA FGKLGCAIRR YLKLCIKLSF GDKITEDSTV EAMVLFLARL
AGFSKAMDVG ASSGPGIHLL CEFAHDSSAE DFCEANVLQL CLTSDIVVPE DFSKEFVAWL
QDVFPKVRLR ALLANLMILP DESAVAVSAH SQSLSLLSEA CQLSKFWKYA VVADLYDLLL
DRDESFVTKL VRHSVMDSAT MNESVLAIFE RVIGAGDDES SAKVIVKVFE SACQLFREDV
DSSLESRVRL MTFMVRLATS HRLIVGKVSK TPSRSLMEPL FELTIGYMRE MMVVLKETDG
SDESAKRKVL FLCGLVDSFL DGIYGPGHSY TSQHGDPSRP FNQGQNADPD GNGSAKPDEN
ERKSSTNSIP SDLDISAGNS TKSLLCTYTT TGSQFVEQHW YFCYSCDLTG SEGVCSVCAR
VCHDGCELAF SKFSRFFCDC GAGSDPQHEN ASNAMSASED GEGGNLAAQD GHSQTLSVIQ
GRRRKLCKCL KSFPSRGDSP SSTHGSEDRK LDSIPECEHD VLSELRLREL LHSEIRTAKE
EGPKSEPNSV PTIQESFERV MKSAETARCL IHTALVLVCE LQLSHSTKNA VCLLPEEAQV
AESINQAVKT PQYVRMPRTT KIARSTRVFK AGCFDMNGMP PSAGSPIIWK GSLISYSSSS
SILAIAQKTG KVQFIDVSET LQHTGNPLEK AIGSSYAQTS VPYDIFHLVF HPENPNLLLV
VGSTRVSVLV RVPQSGGCRW HYVEIELGLV AFDSAESGSI LLDASWVEGK AAYVLITTTN
FVKVFDVTKD NISPCFFAKT PGVNEAGASV GVHTNDGEEE IHEPNSTKAE KIDECSGRTV
RCAFVVPRLV QCETQPILYL VLITSDNLLF VSRCKVDEAD APKFLKLCDL GDTIGDEIKD
PSINGVFYHP TTSLIMVSFK NGSLVGMALA LEPEGEDFRA ATQWVHFYSD AIPAGDNAEL
IPVPGLETIF MFCRKGQSLK SGGVLSVTSD RSMKIHCFSG SPSSSVLGLT TYAPSSVLGR
SAFAGGFILL DDGSLHRVDV ACGPPRPQIS DQSILSTVFE RQRQRALRAS RAHNDGLNGY
HAVPDTVGFF EKCRLVSEQV QILPPFESSE PGPLYERMGV ILAGSSGDCV VSSKENESFD
FSAAISNQSI VLVGARLRFG GSERSRNRVP LEVKVFGRTV RWQAKNGVKR WLDIPFTVPE
STESPQKAHF ELLPRRTMGE SRFSGDGYLA IDSLELYAVS TIEFTERKLL YENEEAKHYE
QLKKQREPAE ERNVKKYSEL LSMASRGTPN SPNSAKFSQE QVALLSLLNS LDSKSFAKQT
GAEAESGTLL LEINNLWSAV FEGSPARDPN FLGHMLKPVL KLCTGSEEAD ALAEFASNTK
ELMSKAVISS TDKMLCSVGC NGVLLHVNDI ERSLFAVGGL CRSLLVAASS VGKLDRDTWK
KTRMEVLPPP SSLYMLLKCH FGLGPAGRSL FTSSYAATTC AVDIFMVEFV RGCLEPEDET
LCTSSMFFSL LIQMLCSFDQ RLRLFISQRL LELFDSLDAA AELTGTPLEA VVGASLSDHL
RTAETSTEHP SSSSETENTN EETESAQRWA YRCDNCREVC DQEWWHCNVC EDFDLCTGCL
RKPGISFDGQ HNEEHLLLRG TAGDDLSSQE SVHGNDEVSD VTLAVQKALG SILDEILSAA
ASEKSSSNIW RYLDGIETVS QLVGKRSHPL LKSFRVESLF QSTFVNFLRR ESENVGNEIE
GTSTEAGLRT IPKNMELLFL VLRIANCAQG GLTPTFLHEC SIPASLVRLL RKFHGKLQIL
VRSLISGQLQ LRKSPAEECS LVSWGTWNNL IPGLAYDVLH QRRSLRPNGK VGALYYLNEE
LGQGNSLFLN LLIAVLEVLE YSFKSASSSS ILTQMSETPR NVLCDIINFC ESTYPYVQDT
TLLKESARAA TRVLSALSFD DVNVLNDTLD KYLYEEQCQH LENAVKSMSG NTNQIVEYDV
SVEIATILET LHKAAETHPA TWRSFVIEND QVLRHIYGAS RLLGGQMRVK ALQLLATGFA
VSDKVASRVI QGLRFVDFDD IALPNSSENP AEAQDDGNVE HEDEPETDCV SAIALSKESQ
HRQQVAVSIF QEKSADILQF LVHKVMLRSQ DAAARRAASH IIILGIARAA AHVEEESFVT
TIHSSLMKGI HLMPYAGELS DGLLDCVQFF IKCCQGDLFD LQSEPLLTSL SFTVTSLMKQ
RCNLLVSHPN ARLYGRLSAL LDINGYYLES DPCMSCSGSV CASSESTECR LDTIRAETKY
TDSSIMHRLL SVHEVSAISV KVVDPRRTRR AKTIDVLFSS RSVADAAELK SVDFPWRKLR
SLELDSKATE ASINLVVPIA AANIKLEFVD FHSLAELPSE SSSGNIDKSS AEPSNSRRSN
SNTGSNENLQ CPRCSRSVTD RHGICRNCHE NAYQCRQCRN INYENLDGFL CNECGYCKHG
RFEFSVIGRP TFVAERIANE EDRKRASKII EKETGNVHRC MDQLTSMRSS IIRSLNSGIP
TEEGRERTKL LGNARVGLAD LLDSVAPRAE IAVLEALLEQ GHAPQEIEEA ANSTQGGISI
TEEVAAESSG SADRSDRDQN NDAGSSVASP VNRNDPSRSA SGDGNVISKS TTALATTYGK
ECRSIYTGMS RGIRVLTLTR AELVRYANSV GGSRLQYANE IVLKKSLPNT DDIETDSATS
GLTRSIPNQR RVACYGCTQS FVSHCVRLVQ CVLRRDGPAT TAIRSSDLCQ YILLVCSLCE
KPEVRGNMRD LITYLVNDNL HATQLVCREL SRKIEFCVDS FETVDSHSVA RFEMGVLEAI
ATLDDSCWEE RLKLVIRILF KSSTQALTCS SVSESIILPC LRVALRLMRT DYDLMVIDSK
APAEEFSGSH DTGDVERPSG HSTGPSDGEP VDDSRSGRNT HTSQPEASSD GDIRRTSEQD
GSGVANTSIG SLEAVRSRIS HIPDNSEQSS STEPTCTQTT ASNLENMFST PEVPSSIGGE
SDLHDSGDEE NNTAPRPRRD ISAEGLSTLL ENDHESKVVT ADVDRWLEGK FDQRSWIAEM
TERSNGQEGG NKRRTGPSQS RAHLGTVFSR WKHLGADSSP GLFSRKDKPK LKPLSIEKDN
WVVRLMLLTP CATVRKEACA LLELICGHEE TLQLQLLDVL TGPAISLGAD AGEHSKEFFD
LLERSLSSRS HRLYLIAKGF LSRLADLIRT RAERLLLSEA SSESSLQLVN FLEGYAVKRL
LSLLRHTLDA IPGQRLSLRE KLFKVNDYKL VGSLERAYIC MRKLISLRTK LTDECGAQLC
EILLSRDLLF AGPSVLAVVS ACVEELKTAK ARKDAQAIGI LLEQLCLMLC PERKEPICHL
SLKKAPTQEE YIRGSMSRNP YASSTFDGPL MRDVKNKICR DLEIPSLLDD DFAMELLVAG
NLVKLDLPIM AVYDHVWRGS SEASMVSNMQ PTQLTRSFGL RRTSHTHPSR GQVSRRSTIL
TLRRLNSDRD VSEDDSRSDG RADPPMVVVY RLSGLDGEAT EPIVDSVPAE SNDEEDAEKM
YGDTIVFGEV GGLEVLFQLL AIVGSWGDDA ETAVRAPALR LLRASCEVAK NRALLAKSAD
TVSTLLDCAA SAFEHAQGSP TAVSSAESLL VAAEQILAQQ RKELESHAST MTDTVTVFSH
DPDEIMSRIQ VFLGRLSVAT SPKAENSILH LLPFLVQGVP SAIGAVLQYF QFACETIDVE
SEGQRKARQL GTVLLATPKD LRGDKFAEQT IRTDVAMNAV QYLVRKFPVP RNTHQEDWAA
ALEYPGPPLV LRLLTGLSLF FGPGQDQYQS GILLKEILGD ETKIIPALCQ LEMAVSGNAI
GTTTEELLDA LGKDGKIKSE IERERSEIKR ARREAAKASR MAILRETGLS KLVRNETPTS
QLSSESVKKG EEEQVESVLK LMDELPDEVG PSCVVCGDGF RCRPEDALAF YVHCRKVPLD
LAGSSYASKE SGPGETSPSG SAQNSGRLEL QLWASGRSRN HGTSTRTGGS SCYATVTHLN
AIHLSCHKEA ARADRSSRRD EWEGAALRNS QTKCNNLFPV RPPVTLEKEA GDDQAAIQKT
ARMSYSAAVD SYFGRLSSIG RTNLSHSKVV IYDIGRSLLR FADGGTMIFS EYARGGGPHS
NACLLPHLVQ LAIHMVEVSP HGEQKSFFDE SRTLQTQEAA LVKFVEEDEV GDVTYYLASA
LVLQSLEKWS TCATVFLRRG IRGGALRLAV LLRLIAFTDL VNRVMKSGVS VADDQHWLES
FRRRIGSDEA FAQEFGDIVN NRWEEYIRSV DDAESLSMAI SRNYEVDNMG HGGQGKALHE
SMKLCIESEC SRPTNTVSKG E
//
