GenomeNet

Database: UniProt/TrEMBL
Entry: S3CWB1_GLAL2
LinkDB: S3CWB1_GLAL2
Original site: S3CWB1_GLAL2 
ID   S3CWB1_GLAL2            Unreviewed;       515 AA.
AC   S3CWB1;
DT   18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT   18-SEP-2013, sequence version 1.
DT   25-APR-2018, entry version 27.
DE   RecName: Full=Glutamate decarboxylase {ECO:0000256|RuleBase:RU361171};
DE            EC=4.1.1.15 {ECO:0000256|RuleBase:RU361171};
GN   ORFNames=GLAREA_01080 {ECO:0000313|EMBL:EPE29920.1};
OS   Glarea lozoyensis (strain ATCC 20868 / MF5171).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Helotiales; Helotiaceae; Glarea.
OX   NCBI_TaxID=1116229 {ECO:0000313|EMBL:EPE29920.1, ECO:0000313|Proteomes:UP000016922};
RN   [1] {ECO:0000313|EMBL:EPE29920.1, ECO:0000313|Proteomes:UP000016922}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 20868 / MF5171 {ECO:0000313|Proteomes:UP000016922};
RX   PubMed=23688303; DOI=10.1186/1471-2164-14-339;
RA   Chen L., Yue Q., Zhang X., Xiang M., Wang C., Li S., Che Y.,
RA   Ortiz-Lopez F.J., Bills G.F., Liu X., An Z.;
RT   "Genomics-driven discovery of the pneumocandin biosynthetic gene
RT   cluster in the fungus Glarea lozoyensis.";
RL   BMC Genomics 14:339-339(2013).
CC   -!- CATALYTIC ACTIVITY: L-glutamate = 4-aminobutanoate + CO(2).
CC       {ECO:0000256|RuleBase:RU361171}.
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|PIRSR:PIRSR602129-50,
CC         ECO:0000256|RuleBase:RU000382};
CC   -!- SIMILARITY: Belongs to the group II decarboxylase family.
CC       {ECO:0000256|RuleBase:RU000382}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; KE145367; EPE29920.1; -; Genomic_DNA.
DR   RefSeq; XP_008084029.1; XM_008085838.1.
DR   EnsemblFungi; EPE29920; EPE29920; GLAREA_01080.
DR   GeneID; 19460138; -.
DR   KEGG; glz:GLAREA_01080; -.
DR   KO; K01580; -.
DR   OrthoDB; EOG092C1P0W; -.
DR   Proteomes; UP000016922; Unassembled WGS sequence.
DR   GO; GO:0004351; F:glutamate decarboxylase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006536; P:glutamate metabolic process; IEA:InterPro.
DR   Gene3D; 3.40.640.10; -; 1.
DR   InterPro; IPR010107; Glutamate_decarboxylase.
DR   InterPro; IPR002129; PyrdxlP-dep_de-COase.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   PANTHER; PTHR43321; PTHR43321; 1.
DR   Pfam; PF00282; Pyridoxal_deC; 1.
DR   SUPFAM; SSF53383; SSF53383; 1.
DR   TIGRFAMs; TIGR01788; Glu-decarb-GAD; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000016922};
KW   Decarboxylase {ECO:0000256|RuleBase:RU361171};
KW   Lyase {ECO:0000256|RuleBase:RU000382};
KW   Pyridoxal phosphate {ECO:0000256|PIRSR:PIRSR602129-50,
KW   ECO:0000256|RuleBase:RU000382};
KW   Reference proteome {ECO:0000313|Proteomes:UP000016922};
KW   Transferase {ECO:0000313|EMBL:EPE29920.1}.
FT   MOD_RES     295    295       N6-(pyridoxal phosphate)lysine.
FT                                {ECO:0000256|PIRSR:PIRSR602129-50}.
SQ   SEQUENCE   515 AA;  58238 MW;  9DB0C08D3E3F12D2 CRC64;
     MVHLASIPTN KDIGKPLVEG MEKLKVAEQS DQDQFTTSVY GSRFASEDLP KHEMPETEMP
     KEVAYRMIKD DLSLDGNPML NLASFVTTYM EKEVEDLMTE SFSKNFIDYE EYPQSADIQN
     RCVSMIGRLF NAPLDGDMAP VGTSTVGSSE AIMLAVLAMK KKWKNARQAA GKPTDRPNIV
     MSSAVQVCWE KAARYFEVEE KYVYCTENRY VIDPEETVSL VDENTIGICV ILGTTYTGQY
     EDAKAVNDLL IKKNIDTVIH IDAASGGFVA PFVVPELEWD FRLEKVVSIN VSGHKYGLVY
     PGVGWVVWRA PEYLPKELVF NINYLGADQS SFTLNFSKGA SQVIGQYYQL IRLGKHGYRA
     IMGNLTRTAD YLAESLEQLG FVLMSEKNGK GLPLVAFRID PKSNKHYDEF AIAHQLRQRS
     WVVPAYTMAP HTNDLKMLRV VVREDFSKSR CDQLLDDIKL CQGVLDKMDK DEIKKHNDFI
     RLNQSHSGRR QNVHPHYRNE KHSLQGKTGK THAAC
//
DBGET integrated database retrieval system