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Database: UniProt/TrEMBL
Entry: U5WZM0_MYCKA
LinkDB: U5WZM0_MYCKA
Original site: U5WZM0_MYCKA 
ID   U5WZM0_MYCKA            Unreviewed;       928 AA.
AC   U5WZM0;
DT   22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT   22-JAN-2014, sequence version 1.
DT   25-OCT-2017, entry version 29.
DE   SubName: Full=AMP-dependent synthetase and ligase {ECO:0000313|EMBL:AGZ53346.1};
GN   ORFNames=MKAN_25875 {ECO:0000313|EMBL:AGZ53346.1};
OS   Mycobacterium kansasii ATCC 12478.
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium.
OX   NCBI_TaxID=557599 {ECO:0000313|EMBL:AGZ53346.1, ECO:0000313|Proteomes:UP000017786};
RN   [1] {ECO:0000313|EMBL:AGZ53346.1, ECO:0000313|Proteomes:UP000017786}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 12478 {ECO:0000313|EMBL:AGZ53346.1,
RC   ECO:0000313|Proteomes:UP000017786};
RG   McGill University Mycobacterium genome consortium;
RA   Veyrier F.J., Behr M.A.;
RT   "Genome sequence of Mycobacterium kansasii.";
RL   Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00258}.
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DR   EMBL; CP006835; AGZ53346.1; -; Genomic_DNA.
DR   RefSeq; WP_023372818.1; NC_022663.1.
DR   ProteinModelPortal; U5WZM0; -.
DR   STRING; 557599.MkanA1_010100015020; -.
DR   EnsemblBacteria; AGZ53346; AGZ53346; MKAN_25875.
DR   GeneID; 29697712; -.
DR   KEGG; mkn:MKAN_25875; -.
DR   eggNOG; ENOG4107RCI; Bacteria.
DR   eggNOG; COG0318; LUCA.
DR   OrthoDB; POG091H0HAF; -.
DR   Proteomes; UP000017786; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR   GO; GO:0016746; F:transferase activity, transferring acyl groups; IEA:InterPro.
DR   GO; GO:0008152; P:metabolic process; IEA:InterPro.
DR   Gene3D; 1.10.1200.10; -; 1.
DR   InterPro; IPR036736; ACP-like_sf.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig.
DR   InterPro; IPR020806; PKS_PP-bd.
DR   InterPro; IPR002123; Plipid/glycerol_acylTrfase.
DR   InterPro; IPR009081; PP-bd_ACP.
DR   Pfam; PF01553; Acyltransferase; 1.
DR   Pfam; PF00501; AMP-binding; 1.
DR   Pfam; PF00550; PP-binding; 1.
DR   SMART; SM00823; PKS_PP; 1.
DR   SMART; SM00563; PlsC; 1.
DR   SUPFAM; SSF47336; SSF47336; 1.
DR   PROSITE; PS50075; ACP_DOMAIN; 1.
DR   PROSITE; PS00455; AMP_BINDING; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000017786};
KW   Ligase {ECO:0000313|EMBL:AGZ53346.1};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    700    722       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN        4     78       Carrier. {ECO:0000259|PROSITE:PS50075}.
SQ   SEQUENCE   928 AA;  99709 MW;  25FDD8B99EFBA9ED CRC64;
     MAGEERDVLA LVRGLVAEVH PHAMPPSVTL DSTFDDLGIG SLELAELLLR VQGKYGVALP
     SDLLASAETP RDLVVAVDRG HPVLAPERGV MVSLPTTEPG GLAPEAASTL NDVLDWHVGA
     TPERMHIRLL DDSGGGTDLT YATLHREAAA VAAGLIAHDV MPGETVAIML PTCRAYFTTF
     AGVVLAGAVP VPVYPPARPS QLADHLRRTT GILTNAGATL LVTVPEAVTL GHLLRANVES
     LRHVVVPETL MGTSEDASPS LPALPRPRSD DLALVQYTSG STGQPKGVAL AHRNLLANIR
     AMGQAAGASG TDTFVSWLPL YHDMGLIGAW LGCMYFGVPL VVMSPQAFLI RPSRWLWAIH
     ANRATMSAGP NFAYELCLAK VRDDEIAGLD LSSWRLAYNG AEPVSPATIE RFADRFAAYG
     FRPDAMTPVY GLAESSVGLA FPPLGRGPLI DRIRRDEFVR SGRAEPAWPG ERDALRFVAC
     GRPLPGHEIR IVDTAGTELG DRREGRIEFR GPSATAGYFN NPTPTRSLFH GDWLDTGDLG
     YMADADLYVT GRVKDLIIRA GRNLHPAELE EAVGNLTGVR KGCVAVFASA DRSGGAERLV
     VVAETRLTED AARAALRSEI ASTTVDLLGV PPDDVVLAPP RTVLKTSSGK IRRAASRQLY
     EAGRIGARPH AVWLELVRLR LRGAAPSLRR TGRAASAVAF AAYTWAVYLV LGLALVLLLL
     LLPRERWRWW AVRRSIRLLA RLTGTAITVH GLNHLPAQTC IAVANHPSWI DGIVLASVLP
     PSFHFVVAEQ LQQGLYGFAL RRLGTQFVER HQREQGVADT DQLVGCARAG QSLVIFPEGR
     LARAPGLRPF HIGAFVVAAE AGVPALPVAI RGTRSVMRPG HHFPRRGAID VVIGMPIRPA
     GRDWDAAVDV QRKAREAVLR MSGEPDVE
//
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