ID   V3ZF70_LOTGI            Unreviewed;       484 AA.
AC   V3ZF70;
DT   22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT   22-JAN-2014, sequence version 1.
DT   07-JUN-2017, entry version 25.
DE   RecName: Full=Phosphotransferase {ECO:0000256|RuleBase:RU362007};
DE            EC=2.7.1.- {ECO:0000256|RuleBase:RU362007};
GN   ORFNames=LOTGIDRAFT_164838 {ECO:0000313|EMBL:ESO89803.1};
OS   Lottia gigantea (Giant owl limpet).
OC   Eukaryota; Metazoa; Lophotrochozoa; Mollusca; Gastropoda;
OC   Patellogastropoda; Lottioidea; Lottiidae; Lottia.
OX   NCBI_TaxID=225164 {ECO:0000313|EMBL:ESO89803.1, ECO:0000313|Proteomes:UP000030746};
RN   [1] {ECO:0000313|EMBL:ESO89803.1, ECO:0000313|Proteomes:UP000030746}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=23254933; DOI=10.1038/nature11696;
RA   Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA   Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA   Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H.,
RA   Aerts A., Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V.,
RA   Lindberg D.R., Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT   "Insights into bilaterian evolution from three spiralian genomes.";
RL   Nature 493:526-531(2013).
CC   -!- SIMILARITY: Belongs to the hexokinase family.
CC       {ECO:0000256|RuleBase:RU362007, ECO:0000256|SAAS:SAAS00672880}.
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DR   EMBL; KB202544; ESO89803.1; -; Genomic_DNA.
DR   RefSeq; XP_009059587.1; XM_009061339.1.
DR   EnsemblMetazoa; LotgiT164838; LotgiP164838; LotgiG164838.
DR   GeneID; 20239841; -.
DR   KEGG; lgi:LOTGIDRAFT_164838; -.
DR   CTD; 20239841; -.
DR   KO; K00844; -.
DR   OMA; MIPTFVT; -.
DR   OrthoDB; EOG091G08MD; -.
DR   Proteomes; UP000030746; Unassembled WGS sequence.
DR   GO; GO:0005623; C:cell; IEA:GOC.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0005536; F:glucose binding; IEA:InterPro.
DR   GO; GO:0004396; F:hexokinase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0001678; P:cellular glucose homeostasis; IEA:InterPro.
DR   GO; GO:0006096; P:glycolytic process; IEA:UniProtKB-KW.
DR   InterPro; IPR001312; Hexokinase.
DR   InterPro; IPR022673; Hexokinase_C.
DR   InterPro; IPR022672; Hexokinase_N.
DR   PANTHER; PTHR19443; PTHR19443; 1.
DR   Pfam; PF00349; Hexokinase_1; 1.
DR   Pfam; PF03727; Hexokinase_2; 1.
DR   PROSITE; PS51748; HEXOKINASE_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|RuleBase:RU362007,
KW   ECO:0000256|SAAS:SAAS00672869};
KW   Complete proteome {ECO:0000313|Proteomes:UP000030746};
KW   Glycolysis {ECO:0000256|RuleBase:RU362007,
KW   ECO:0000256|SAAS:SAAS00672870};
KW   Kinase {ECO:0000256|RuleBase:RU362007, ECO:0000256|SAAS:SAAS00672871};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU362007,
KW   ECO:0000256|SAAS:SAAS00672883};
KW   Reference proteome {ECO:0000313|Proteomes:UP000030746};
KW   Transferase {ECO:0000256|RuleBase:RU362007,
KW   ECO:0000256|SAAS:SAAS00672884}.
FT   DOMAIN       34    227       Hexokinase_1. {ECO:0000259|Pfam:PF00349}.
FT   DOMAIN      235    469       Hexokinase_2. {ECO:0000259|Pfam:PF03727}.
SQ   SEQUENCE   484 AA;  54277 MW;  33726DBD760BB767 CRC64;
     MTSHGKFRSS SGKGSRRSSV KKIVTDPKER QRLVENILKP FILEDSVYDK VCDVMLDNFN
     KGLGKDTNAD ARVKMFPTYV RSVPNGTEEG NFLALDLGGT NFRVLLINLN GQEVDMESKI
     YLIPQHIMLG TGVQLFDHIA DCIYKFMKEH KLENKKLPLG FTFSFPCKQL GLAEAHLTTW
     TKGFKCEGVE GKDIVTLLHD AIKRKGDMHV ECLAVINDTV GALMSCAHSD RQCGIGLILG
     TGTNACYIER LENVELWDAD YEEPKQVIIN TEWGALGDNG DLDFLITEYD KHVDKHSINA
     GKQIYEKMIS GMYMGEIVRL VLEKLRKNGL LFNGKGSEEL STRGRFYTKY VSEIESDVDE
     SDFKSTKQVF DELNLTDYTD QDCRIALHVC SLVSKRAAYL ASAGIATLLN KMERKDVSVA
     VDGSLYRFHP HFHDLMVEKI QKLIKPGLRF KLMLSHDGSG KGAALVAAVA NRLKEEALQK
     NSED
//