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Database: UniProt/TrEMBL
Entry: W5P5B2_SHEEP
LinkDB: W5P5B2_SHEEP
Original site: W5P5B2_SHEEP 
ID   W5P5B2_SHEEP            Unreviewed;       500 AA.
AC   W5P5B2;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   30-AUG-2017, entry version 22.
DE   SubName: Full=4-aminobutyrate aminotransferase {ECO:0000313|Ensembl:ENSOARP00000005615};
GN   Name=ABAT {ECO:0000313|Ensembl:ENSOARP00000005615};
OS   Ovis aries (Sheep).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;
OC   Pecora; Bovidae; Caprinae; Ovis.
OX   NCBI_TaxID=9940 {ECO:0000313|Ensembl:ENSOARP00000005615, ECO:0000313|Proteomes:UP000002356};
RN   [1] {ECO:0000313|Ensembl:ENSOARP00000005615, ECO:0000313|Proteomes:UP000002356}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Texel {ECO:0000313|Ensembl:ENSOARP00000005615};
RX   PubMed=20809919; DOI=10.1111/j.1365-2052.2010.02100.x;
RA   Archibald A.L., Cockett N.E., Dalrymple B.P., Faraut T., Kijas J.W.,
RA   Maddox J.F., McEwan J.C., Hutton Oddy V., Raadsma H.W., Wade C.,
RA   Wang J., Wang W., Xun X.;
RT   "The sheep genome reference sequence: a work in progress.";
RL   Anim. Genet. 41:449-453(2010).
RN   [2] {ECO:0000313|Ensembl:ENSOARP00000005615}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2014) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the class-III pyridoxal-phosphate-dependent
CC       aminotransferase family. {ECO:0000256|RuleBase:RU003560}.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSOARP00000005615}.
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DR   EMBL; AMGL01068286; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_004020808.1; XM_004020759.3.
DR   RefSeq; XP_011959472.1; XM_012104082.2.
DR   ProteinModelPortal; W5P5B2; -.
DR   Ensembl; ENSOART00000005703; ENSOARP00000005615; ENSOARG00000005228.
DR   GeneID; 101105462; -.
DR   KEGG; oas:101105462; -.
DR   CTD; 18; -.
DR   GeneTree; ENSGT00550000074885; -.
DR   KO; K13524; -.
DR   OMA; ALGMNHP; -.
DR   OrthoDB; EOG091G08T5; -.
DR   Proteomes; UP000002356; Chromosome 24.
DR   GO; GO:0032144; C:4-aminobutyrate transaminase complex; IEA:Ensembl.
DR   GO; GO:0070062; C:extracellular exosome; IEA:Ensembl.
DR   GO; GO:0005739; C:mitochondrion; IEA:Ensembl.
DR   GO; GO:0003867; F:4-aminobutyrate transaminase activity; IEA:Ensembl.
DR   GO; GO:0042803; F:protein homodimerization activity; IEA:Ensembl.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:Ensembl.
DR   GO; GO:0048148; P:behavioral response to cocaine; IEA:Ensembl.
DR   GO; GO:0009448; P:gamma-aminobutyric acid metabolic process; IEA:InterPro.
DR   CDD; cd00610; OAT_like; 1.
DR   Gene3D; 3.40.640.10; -; 1.
DR   Gene3D; 3.90.1150.10; -; 2.
DR   InterPro; IPR004631; 4NH2But_aminotransferase_euk.
DR   InterPro; IPR005814; Aminotrans_3.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major_sub1.
DR   InterPro; IPR015422; PyrdxlP-dep_Trfase_sub2.
DR   Pfam; PF00202; Aminotran_3; 1.
DR   PIRSF; PIRSF000521; Transaminase_4ab_Lys_Orn; 1.
DR   SUPFAM; SSF53383; SSF53383; 1.
DR   TIGRFAMs; TIGR00699; GABAtrns_euk; 1.
DR   PROSITE; PS00600; AA_TRANSFER_CLASS_3; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000002356};
KW   Pyridoxal phosphate {ECO:0000256|RuleBase:RU003560};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002356}.
SQ   SEQUENCE   500 AA;  56589 MW;  ACAFBB39BAA1E268 CRC64;
     MASMLLTQRL VCSFQHNYRL LVPGSRHISQ AAAKVDVEFD YDGPLMKTEV PGPRSRELMK
     QLNIIQNAEA VHFFCNYEES RGNYLVDVDG NRMLDLYSQI SSVPIGYNHP ALMKLVQQPQ
     NMSTFINRPA LGILPPENFV EKLRESLLSV APKGMSQLIT MACGSCSNEN AFKTIFMWYR
     SKERGQSSFS KEELETCMVN QAPGCPDYSI LSFMGAFHGR TMGCLATTHS KAIHKIDIPS
     FDWPIAPFPR LKYPLEEFVK ENQQEEARCL EEVEDLIVKY RKKKRTVAGI IVEPIQSEGG
     DNHASDDFFR KLRDISRKHG CAFLVDEVQT GGGCTGKFWA HEHWGLDDPA DVMTFSKKMM
     TGGFFHKEEL RPNAPYRIFN TWLGDPSKNL LLAEVINVIK REDLLNNAAH AGKVLLTGLL
     DLQARFPQLI SRVRGRGTFC SFDTPDESVR NKLISIARNK GLMLGGCGDK SIRFRPTLVF
     RDHHAHLFLN VFSDILADFK
//
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