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Database: UniProt/TrEMBL
Entry: W9BMV5_KLEPN
LinkDB: W9BMV5_KLEPN
Original site: W9BMV5_KLEPN 
ID   W9BMV5_KLEPN            Unreviewed;       421 AA.
AC   W9BMV5;
DT   14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT   14-MAY-2014, sequence version 1.
DT   20-DEC-2017, entry version 41.
DE   SubName: Full=4-aminobutyrate aminotransferase {ECO:0000313|EMBL:ALR25607.1};
DE   SubName: Full=4-aminobutyrate aminotransferase PuuE {ECO:0000313|EMBL:KMW83988.1};
DE   SubName: Full=Aspartate aminotransferase family protein {ECO:0000313|EMBL:OSW36012.1};
DE            EC=2.6.1.19 {ECO:0000313|EMBL:ALR25607.1, ECO:0000313|EMBL:OXT24760.1};
GN   ORFNames=AGG09_15685 {ECO:0000313|EMBL:ALR25607.1}, B1727_04730
GN   {ECO:0000313|EMBL:OXT24760.1}, B4U22_28785
GN   {ECO:0000313|EMBL:OWF99707.1}, B8011_09015
GN   {ECO:0000313|EMBL:OVH59117.1}, BL102_0021465
GN   {ECO:0000313|EMBL:OSW36012.1}, BN49_0292
GN   {ECO:0000313|EMBL:CDO12060.1}, BVX91_06685
GN   {ECO:0000313|EMBL:PAX13723.1}, CEO55_20165
GN   {ECO:0000313|EMBL:OZL84824.1}, SM57_04067
GN   {ECO:0000313|EMBL:KMW83988.1};
OS   Klebsiella pneumoniae.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Klebsiella.
OX   NCBI_TaxID=573 {ECO:0000313|EMBL:CDO12060.1, ECO:0000313|Proteomes:UP000032739};
RN   [1] {ECO:0000313|EMBL:CDO12060.1, ECO:0000313|Proteomes:UP000032739}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CIP 52.145 {ECO:0000313|Proteomes:UP000032739}, and Kp52.145
RC   {ECO:0000313|EMBL:CDO12060.1};
RX   PubMed=25341126; DOI=10.3201/eid2011.140206;
RA   Bialek-Davenet S., Criscuolo A., Ailloud F., Passet V., Jones L.,
RA   Delannoy-Vieillard A.S., Garin B., Le Hello S., Arlet G.,
RA   Nicolas-Chanoine M.H., Decr D., Brisse S.;
RT   "Genomic Definition of Hypervirulent and Multidrug-Resistant
RT   Klebsiella pneumoniae Clonal Groups.";
RL   Emerg. Infect. Dis. 20:1812-1820(2014).
RN   [2] {ECO:0000313|EMBL:KMW83988.1, ECO:0000313|Proteomes:UP000037134}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGH83 {ECO:0000313|EMBL:KMW83988.1,
RC   ECO:0000313|Proteomes:UP000037134};
RG   The Broad Institute Genomics Platform;
RG   The Broad Institute Genome Sequencing Center for Infectious Disease;
RA   Earl A.M., Onderdonk A.B., Kirby J., Ferraro M.J., Huang S.,
RA   Spencer M., Fodor A., Hooper D., Dekker J., O'Brien T., Quan V.,
RA   Gombosev A., Delaney M., Dubois A., Ernst C., Kim D.S., Rossman W.,
RA   Gohs F., Petruso H., Nozar T., Mougeot F., Manson-Mcguire A.,
RA   Young S., Abouelleil A., Cao P., Chapman S.B., Griggs A., Priest M.,
RA   Shea T., Wortman I., Wortman J.R., Nusbaum C., Birren B.;
RT   "The Genome Sequence of None.";
RL   Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|Proteomes:UP000067608}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CAV1193 {ECO:0000313|Proteomes:UP000067608};
RA   Sheppard A.E., Stoesser N., Sebra R., Kasarskis A., Deikus G.,
RA   Anson L., Walker A.S., Peto T.E., Crook D.W., Mathers A.J.;
RT   "Complete Genome Sequence of the KPC-producing Klebsiella pneumoniae
RT   strain CAV1193.";
RL   Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
RN   [4] {ECO:0000313|EMBL:ALR25607.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=CAV1193 {ECO:0000313|EMBL:ALR25607.1};
RX   PubMed=26823590;
RA   Sheppard A.E., Stoesser N., Sebra R., Kasarskis A., Deikus G.,
RA   Anson L., Walker A.S., Peto T.E., Crook D.W., Mathers A.J.;
RT   "Complete Genome Sequence of KPC-Producing Klebsiella pneumoniae
RT   Strain CAV1193.";
RL   Genome Announc. 4:e01649-15(2016).
RN   [5] {ECO:0000313|EMBL:OXT24760.1, ECO:0000313|Proteomes:UP000215037}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=OK8 {ECO:0000313|EMBL:OXT24760.1,
RC   ECO:0000313|Proteomes:UP000215037};
RA   Nagamalleswari E., Nagaraja V.;
RT   "Draft genome analysis of Klebsiella pneumoniae OK8.";
RL   Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
RN   [6] {ECO:0000313|EMBL:OVH59117.1, ECO:0000313|Proteomes:UP000195917}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=42812 {ECO:0000313|EMBL:OVH59117.1,
RC   ECO:0000313|Proteomes:UP000195917};
RA   Afonso C.L., Miller P.J., Scott M.A., Spackman E., Goraichik I.,
RA   Dimitrov K.M., Suarez D.L., Swayne D.E.;
RL   Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
RN   [7] {ECO:0000313|EMBL:OWF99707.1, ECO:0000313|Proteomes:UP000196744}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1830 {ECO:0000313|EMBL:OWF99707.1,
RC   ECO:0000313|Proteomes:UP000196744};
RA   Martins R.C., Perdigao-Neto L.V., Costa S.F., Levin A.S.;
RT   "Klebsiella pneumoniae genome sequencing and assembly.";
RL   Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
RN   [8] {ECO:0000313|EMBL:OSW36012.1, ECO:0000313|Proteomes:UP000186660}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=682_1613 {ECO:0000313|EMBL:OSW36012.1,
RC   ECO:0000313|Proteomes:UP000186660};
RA   Afonso C.L., Miller P.J., Scott M.A., Spackman E., Goraichik I.,
RA   Dimitrov K.M., Suarez D.L., Swayne D.E.;
RL   Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
RN   [9] {ECO:0000313|EMBL:OZL84824.1, ECO:0000313|Proteomes:UP000216878}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=L222 {ECO:0000313|EMBL:OZL84824.1,
RC   ECO:0000313|Proteomes:UP000216878};
RA   Zheng B.;
RT   "Whole-Genome Sequencing Reveals the Clonal Transmission of Intestinal
RT   Carriage of Carbapenemase-producing Enterobacteriaceae in Hospitalized
RT   Patients with Diarrhea.";
RL   Submitted (JUL-2017) to the EMBL/GenBank/DDBJ databases.
RN   [10] {ECO:0000313|EMBL:PAX13723.1, ECO:0000313|Proteomes:UP000218240}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WBB417 {ECO:0000313|EMBL:PAX13723.1,
RC   ECO:0000313|Proteomes:UP000218240};
RA   Koh T.H., Abdul Rahman N., Teo J.W., La M.-V., Periaswamy B.,
RA   Chen S.L.;
RT   "Draft Genome Sequence of a Singapore Klebsiella pneumoniae subsp.
RT   pnuemoniae isolate DS32358_14 Encoding the Carbapenemase Gene blaVIM-
RT   1.";
RL   Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the class-III pyridoxal-phosphate-dependent
CC       aminotransferase family. {ECO:0000256|RuleBase:RU003560}.
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DR   EMBL; CP013322; ALR25607.1; -; Genomic_DNA.
DR   EMBL; FO834906; CDO12060.1; -; Genomic_DNA.
DR   EMBL; LGJJ01000013; KMW83988.1; -; Genomic_DNA.
DR   EMBL; MPXL03000093; OSW36012.1; -; Genomic_DNA.
DR   EMBL; NDCY01000042; OVH59117.1; -; Genomic_DNA.
DR   EMBL; NBSB01001899; OWF99707.1; -; Genomic_DNA.
DR   EMBL; MZXR01000041; OXT24760.1; -; Genomic_DNA.
DR   EMBL; NLDJ01000022; OZL84824.1; -; Genomic_DNA.
DR   EMBL; NSMB01000004; PAX13723.1; -; Genomic_DNA.
DR   RefSeq; WP_002920814.1; NZ_NQLN01000022.1.
DR   EnsemblBacteria; ALR25607; ALR25607; AGG09_15685.
DR   EnsemblBacteria; CDO12060; CDO12060; BN49_0292.
DR   KEGG; kpb:FH42_15460; -.
DR   KEGG; kpne:KU54_001485; -.
DR   KEGG; kpnu:LI86_01480; -.
DR   PATRIC; fig|573.1347.peg.2677; -.
DR   eggNOG; ENOG4108JPW; Bacteria.
DR   eggNOG; COG0160; LUCA.
DR   KO; K00823; -.
DR   Proteomes; UP000032739; Chromosome.
DR   Proteomes; UP000037134; Unassembled WGS sequence.
DR   Proteomes; UP000067608; Chromosome.
DR   Proteomes; UP000186660; Unassembled WGS sequence.
DR   Proteomes; UP000195917; Unassembled WGS sequence.
DR   Proteomes; UP000196744; Unassembled WGS sequence.
DR   Proteomes; UP000215037; Unassembled WGS sequence.
DR   Proteomes; UP000216878; Unassembled WGS sequence.
DR   Proteomes; UP000218240; Unassembled WGS sequence.
DR   GO; GO:0034386; F:4-aminobutyrate:2-oxoglutarate transaminase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0009448; P:gamma-aminobutyric acid metabolic process; IEA:InterPro.
DR   CDD; cd00610; OAT_like; 1.
DR   Gene3D; 3.40.640.10; -; 1.
DR   Gene3D; 3.90.1150.10; -; 2.
DR   InterPro; IPR004632; 4NH2But_aminotransferase_bac.
DR   InterPro; IPR005814; Aminotrans_3.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major_sub1.
DR   InterPro; IPR015422; PyrdxlP-dep_Trfase_sub2.
DR   Pfam; PF00202; Aminotran_3; 1.
DR   PIRSF; PIRSF000521; Transaminase_4ab_Lys_Orn; 2.
DR   SUPFAM; SSF53383; SSF53383; 1.
DR   TIGRFAMs; TIGR00700; GABAtrnsam; 1.
DR   PROSITE; PS00600; AA_TRANSFER_CLASS_3; 1.
PE   3: Inferred from homology;
KW   Aminotransferase {ECO:0000313|EMBL:ALR25607.1};
KW   Complete proteome {ECO:0000313|Proteomes:UP000032739,
KW   ECO:0000313|Proteomes:UP000037134, ECO:0000313|Proteomes:UP000067608,
KW   ECO:0000313|Proteomes:UP000186660};
KW   Pyridoxal phosphate {ECO:0000256|RuleBase:RU003560};
KW   Transferase {ECO:0000313|EMBL:ALR25607.1}.
SQ   SEQUENCE   421 AA;  44926 MW;  3B1F5D8016FDD5A5 CRC64;
     MKSSELNQRR QQATPRGVGV MCNYFVEKAE NATLWDIEGN EVIDFAAGIA VLNTGHRHPK
     VVAAVADQLQ AFTHTAYQIV PYESYVSLAE RINDLAPIDG PAKTAFFTTG AEAVENAVKI
     ARAYTGRPGL ITFGGGFHGR TFMTMALTGK VAPYKIGFGP FPGSVYHGVY PNAAHGVTTA
     DALKSLERIF KADIAPDQVA AIILEPIQGE GGFNVAPADF MQALRDLCDT HGILLIADEV
     QTGFARTGKL FAMQHYEVKP DLMTMAKSLA GGFPLSGVVG RAEVMDAPAP GGLGGTYAGN
     PLAVAAAHAV LDVIAEEQLC QRAEQLGSHL QEVLNQARAT CPAIVDVRGR GSMVAVEFND
     PQTGEPSPEF TRLVQQKAQE NGLLLLSCGV YGNVIRFLYP LTIPDAQFSK ALDILARVLK
     S
//
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