| Entry |
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| Gene name |
plcb2
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| Definition |
(RefSeq) phospholipase C, beta 2
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| KO |
| phosphatidylinositol phospholipase C, beta [EC: 3.1.4.11] |
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| Organism |
tru Takifugu rubripes (torafugu)
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| Pathway |
| Inositol phosphate metabolism | | Metabolic pathways | | Calcium signaling pathway | | Phosphatidylinositol signaling system | | Adrenergic signaling in cardiomyocytes | | Vascular smooth muscle contraction | | Wnt signaling pathway | | Gap junction | | GnRH signaling pathway | | Melanogenesis | | AGE-RAGE signaling pathway in diabetic complications |
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| Module |
| Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 |
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| Brite |
KEGG Orthology (KO) [BR:tru00001]
Metabolism
Carbohydrate metabolism
00562 Inositol phosphate metabolism
101076025 (plcb2)
Environmental Information Processing
Signal transduction
04310 Wnt signaling pathway
101076025 (plcb2)
04020 Calcium signaling pathway
101076025 (plcb2)
04070 Phosphatidylinositol signaling system
101076025 (plcb2)
Cellular Processes
Cellular community
04540 Gap junction
101076025 (plcb2)
Organismal Systems
Endocrine system
04912 GnRH signaling pathway
101076025 (plcb2)
04916 Melanogenesis
101076025 (plcb2)
Circulatory system
04261 Adrenergic signaling in cardiomyocytes
101076025 (plcb2)
04270 Vascular smooth muscle contraction
101076025 (plcb2)
Human Diseases
Endocrine and metabolic diseases
04933 AGE-RAGE signaling pathway in diabetic complications
101076025 (plcb2)
Enzymes [BR:tru01000]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
101076025 (plcb2)
Membrane trafficking [BR:tru04131]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
101076025 (plcb2)
Endocytosis
Macropinocytosis
Phospholipase C
101076025 (plcb2)
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| SSDB |
   |
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| Motif |
 |
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| Other DBs |
NCBI-ProteinID: NCBI-GeneID: |
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| Position |
2
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| AA seq |
1199 aa  
MNQKRHFLEPPEVKDYMVKGERFTKWSEDSTKTAPVTMKMDPKGFYLYWINQSKETTFLD
VATIRDTRTGKYAKLPKHPKVRNVFNLDFPDSNHLAKTLTVVSGPDTVNLTYHNFFASKE
KVTQNWANDIIALAYNAARNNACKQVFLEKIYVRVSLHTNKDGKIPVKNIYKMFPADKKR
VESALASAHLPKGKYDTMKPDVFTEAAFKVFLANLCPRPEILEIFTSYSNKPTMTKENFT
KFLNEKQRDSRLNEELFPRLRQDQVKALIDKYEPCSSNSNRSLISPEGLLNFLTGPETSV
VILDRLAKWQDMTQPLPHYFVKSSHNTYLTAGQFSGVSSPEMYRQCLLAGCRCLELDCWK
GKPPDEEPIITHGFTMTTEILFKDVIEAIAESAFKTSQYPVILSFENHVDTVKQQEKMAN
YCKTIFGEALLTEPLDKYPLKPGCQIPSPSELMGKILIKNKKSSNETQTHTKKTQDAAST
ATSTQENQASSEGGAAAEDTEEQEDTEEQDEEKMKTSDEGTAGQEVTAFEAMSSLVNYIQ
PNKFISFDNARKKNKSYVISSFVETKGESMIAKNAVEFVEYNKRQMSRIYPKGTRVDSSN
YSPQPFWNVGCQMVALNYQTMDFPMQLNMALFEFNGRTGYLLKHDVLRRSDKTFNPFCDR
IDTVVASTLTIKIYSGQFLSDKNVKTGIEVEVIGLPGDPKKKFRTKWSPTPNSINPVWNE
EPFVFEKILLPEMASLRIVAHEENGKFLGHRIIPLDAIQSGFHHICLHSESNMPLTLPSV
FVYIEVKDYIPAAFADFTDALFNPTKGNEKTSKTPKESSSDYISPYELPLMTQTSANDAK
EAESPAAEKAAAPTPPADVGEESTEPRPETSTADPAENVPEAEATCSEPAADAAAEEASP
DPGPVTAEPPPEAGPPADAAAEQEEVPEPEVSNEDTTSDPDTNTEPSPGDNAAAGAANEA
ANEAANEAANEAAAVAGAAGGAAQSAGGEGSAPAQMCGEEHATVTAEELTQHKNYLKAIK
RQERDMKAAEKKYQKKSEDLIQKYSDTFKAIKKKISLKKTEGGENSTDSGVKSERVQDHK
EKMLAELQLQWKEQCDHLRKKKEQFATERLAVLLEMATERHNSELKMLESEPKDNKKKTK
CSDKAKLKRAMSTELLDGPCLMACSLEEEGLSGALVTMEGSTGRSTQGQMIDMYKDCDQ |
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| NT seq |
3600 nt  +upstreamnt +downstreamnt
atgaaccagaagaggcactttttagagcctccggaggtcaaggactacatggtcaaagga
gagcgattcaccaaatggtcagaggactccacaaagactgctcctgtcaccatgaagatg
gacccgaaaggattctacctctactggatcaaccaaagcaaggagacaacgttcctggat
gttgctactatcagagataccagaacaggaaaatatgccaaacttccaaaacaccctaaa
gttcgcaacgtgtttaacctggacttccctgacagcaaccatctcgccaagactctgact
gtcgtctcgggaccagacacggtcaatttgacctatcacaacttctttgcctctaaggag
aaggtgacacagaactgggccaatgacatcattgcacttgcgtataacgctgccaggaac
aacgcatgcaaacaagtcttcctggagaaaatatacgttcgcgtttccctccacaccaac
aaggacggcaagatcccggtgaaaaacatctacaagatgttcccggcagataagaaaaga
gttgaaagtgcgttggcatcggcccacctccccaaaggaaagtacgacaccatgaagcct
gatgtcttcactgaggctgccttcaaggtctttctggccaacctctgccctcgtcctgag
atcctagagatcttcacctcttattccaacaaaccgaccatgacgaaggaaaacttcact
aaattcctcaacgagaagcagagggactcccggctcaacgaggagctcttcccgcgcctg
cggcaggaccaggtcaaggccctgatcgacaaatacgagccctgctcctccaactcgaac
agaagtctcatttctcctgaaggcctcttaaatttcctgactggtccagagacatccgtg
gtgattctggaccggctggccaagtggcaggacatgacccaaccgttaccccactacttc
gtcaagtcctcccacaacacatacctgacagctggtcagttctccggcgtgtcctcgccc
gagatgtaccgacagtgtctgttggccggctgccgctgcctggagctggactgctggaag
ggcaaacccccagatgaagagcccatcattacccacggcttcaccatgacgactgagatc
ctcttcaaggacgtaatcgaggctatcgctgagagcgctttcaagacctcccagtatcct
gtcatcctctcgttcgagaaccatgttgacacagtgaaacagcaggagaaaatggcaaac
tactgcaaaaccatatttggtgaggccctgctaacagagccgctggacaaataccccctg
aagccgggctgccagatccccagtccatctgagctgatgggcaagatcctcatcaagaac
aagaagagcagcaatgaaacccagacacatactaaaaaaacccaggatgctgccagcaca
gctaccagcacgcaggagaaccaggctagttcagaggggggcgctgctgcggaggacacc
gaggagcaggaggacacggaggagcaggatgaggagaaaatgaagacgtcagatgagggc
acagctggacaggaagtgacagctttcgaagcgatgtcgtccctggtcaactacatccag
cccaacaaattcatctcttttgacaacgccagaaagaaaaacaagagttatgtcatctca
tctttcgtggagacaaaaggggagtcaatgattgccaagaatgctgttgaatttgttgaa
tataataaaaggcagatgagcaggatttaccctaaaggaacaagagtggattcgtctaat
tacagcccacagcctttctggaacgtcggctgccagatggtggcgctcaactaccagacc
atggatttccccatgcagctgaacatggctctgtttgagttcaacggcagaaccggttac
ctgctcaagcatgacgtgttgcgtcgcagtgacaagacgtttaaccctttctgcgacagg
atagacacagttgtggcaagcacgctcaccataaagatttattcaggccagtttttgtct
gacaaaaatgtgaaaaccggcatcgaggtggaggtgattgggctgccgggggaccccaag
aagaaatttcgcaccaagtggtcccccacacccaacagtattaacccggtgtggaacgag
gagccttttgtgttcgaaaagatcctgcttccagaaatggcctctctgagaattgtggct
cacgaagagaacggtaaattcttgggacacaggatcatcccccttgatgccatccaatca
ggtttccatcacatctgcctgcacagtgagagcaacatgccgctcactctgccctctgtc
ttcgtgtacatcgaggtcaaggactacatccctgctgcattcgcagattttacagatgcc
ttattcaatccaacaaagggcaacgagaaaacctcaaagaccccgaaggagtcctcctca
gactacattagtccttatgagctgcctctcatgactcagacctctgcaaacgatgcaaag
gaagctgaatctccggctgcagaaaaggctgcagcaccaacaccaccagccgatgtagga
gaggagtcgactgaacctcgaccagaaacaagcacggccgatcctgcagagaacgtgcca
gaagctgaagcaacctgctccgaacctgctgcagacgcagcagctgaggaggcgtctcca
gatccaggccctgtcacagctgaacccccccctgaagctggtccgcccgcagacgcggct
gcagagcaggaagaggttccagagccggaggtgtccaacgaggacacaaccagcgacccc
gacacaaacacagagccgtctccaggtgacaacgctgcagccggcgctgctaacgaagct
gctaacgaagctgctaatgaagctgctaacgaagctgctgctgtagctggtgcggctggc
ggagcggcccagtccgccggaggtgaaggctcagccccggcgcagatgtgcggtgaagag
cacgccacggtgacagctgaggaactgacacagcacaagaactacctgaaggccatcaaa
cgccaggagagagacatgaaggcggcagagaagaaatatcagaaaaagagcgaggatctg
atccagaaatactccgacaccttcaaggccatcaagaagaagatctcattgaagaaaaca
gagggaggggaaaactccacggacagcggcgtgaagagcgagcgtgtgcaggaccataaa
gaaaaaatgctggctgagctgcagctgcagtggaaggaacagtgtgaccatctgaggaag
aagaaggagcagtttgcaacagagaggctggccgtgctgctggagatggcaacagagcgg
cacaacagtgaactgaagatgctggagagtgaacccaaagataacaagaagaaaaccaaa
tgctcggacaaagccaagttgaaaagggcgatgagcacagagctgttggatgggccttgt
ttgatggcttgttcgctggaggaggagggtctgagcggggccctggtcaccatggagggg
tcgacaggaagaagcacacaaggacaaatgattgacatgtacaaagactgtgaccagtaa |
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