KEGG T00170: TTC1754

Thermus thermophilus HB27: TTC1754

Entry

TTC1754 CDS T00170

Definition

branched-chain alpha-keto acid dehydrogenase subunit E2 (EC:2.3.1.12)

Orthology

K00627

pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase) [EC:2.3.1.12]

Organism

tth Thermus thermophilus HB27

Pathway

tth00010	Glycolysis / Gluconeogenesis
tth00020	Citrate cycle (TCA cycle)
tth00620	Pyruvate metabolism
tth01100	Metabolic pathways
tth01110	Biosynthesis of secondary metabolites
tth01120	Microbial metabolism in diverse environments

Module

tth_M00307

Pyruvate oxidation, pyruvate => acetyl-CoA

Class

Metabolism; Carbohydrate metabolism; Glycolysis / Gluconeogenesis [PATH:tth00010]
Metabolism; Carbohydrate metabolism; Citrate cycle (TCA cycle) [PATH:tth00020]
Metabolism; Carbohydrate metabolism; Pyruvate metabolism [PATH:tth00620]

SSDB

Motif

Pfam:

2-oxoacid_dh Biotin_lipoyl E3_binding Biotin_lipoyl_2

Other DBs

NCBI-GI:

46200056

NCBI-GeneID:

2775168

UniProt:

Q72GU4

Structure

PDB:

2EQ9

Position

complement(1664234..1665589)

AA seq 451 aa
MPKEILMPELAESVVEGEILKWLVEEGDYLKKDQPFVEVMTDKVTVELPSPYEGVLLKKL
AKEGEVVKVHAPIALIAEPGEAVEGVKEPPPVQAVEERSIVEPGLPAKEEKEDLSLFKPD
PTQVAVKNPFLSGEKPQEGARPGRVLAVPAARKLARELGIPIEEVPGSGPLGRVRVEDVR
AYAERRKAPPERPEEGPQVLPAGFPPPPKYAPPKGYEHLEERVPLRGIRRTIAQGLWQSH
LYTVRTLNVDEADLTELVRLRERLKPQAEAQGVKLTYLPFIVKAVVRALKKFPMLNTSLD
EERQEIVYKRYYHIGLAVATERGLIVPVVRDADRKSVLELAQEIAELSQKAREGRLAPEE
VTGSTFTITNIGSVGATLSFPIIHLPDAAILGVHSIRKRPWVMPDGSIRPRDIMFLSLSF
DHRLVDGAEAAMFTREVIRLLENPDLLLLEM

NT seq 1356 nt +upstreamnt +downstreamnt
atgcccaaggaaatcctcatgcccgagctcgccgaaagcgtggtggaaggcgagattctg
aagtggctcgtggaggaaggggactacctgaagaaggaccagcccttcgtggaggtcatg
accgacaaggttacggtggagctgccctccccttacgagggggtgctcctgaagaagctg
gccaaggaaggggaggtggtcaaggtccacgcccccatcgccctcatcgccgagcccggc
gaggcggtggagggcgtgaaggagccccccccggtgcaggcggtggaggagcgctccatc
gtggagccgggcctgcccgcgaaggaggagaaggaggacctctccctcttcaagccggac
cccacgcaggtggcggtgaaaaaccccttcctctccggggaaaagccccaggagggggcg
aggccggggcgggtcctcgccgtccccgccgcccggaagctcgcccgggagctcgggatc
cccattgaggaggtgccgggctcggggcctttgggcagggtccgggtggaggacgtccgg
gcctacgccgagcggaggaaagcccctcccgaaaggcccgaggaggggccccaggtgctt
cctgccggcttcccgcccccgcccaagtacgccccgcccaaggggtacgagcacctggag
gagcgggtgcctctaaggggcatccgccgcaccatcgcccaggggctctggcagagccac
ctctacacggtgcgcaccctcaacgtggacgaggccgacctcacggagctcgtgcgcctg
cgcgagcgcctcaagccccaggccgaggcccagggggtcaagctcacctacctgcccttc
atcgtcaaggcagtggtgcgggccctgaagaagttccccatgctgaacaccagcctggac
gaggaaaggcaggagatcgtctacaagcgctactaccacatcggcctcgccgtggccacg
gaaaggggcctcatcgtccccgtggtgcgggatgcggaccggaagagcgtcttggagctc
gcccaggagatcgccgagctctcccagaaggcgcgggaaggccgcctcgccccggaggag
gttacggggtccaccttcaccatcaccaacatcggctccgtgggggccaccttgagcttc
cccatcatccacctgccggacgcggccatcctcggcgtgcactccataaggaagcgcccc
tgggtcatgccggacggttccataaggccgcgggacatcatgttcctctccctctccttt
gaccaccgcctggtggacggggccgaggcggccatgttcacccgggaggtcatcaggctc
ttggaaaaccccgacctgctccttctggaaatgtag

All links

Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
3D Structure (1)   
   PDB (1)   
Protein domain (4)   
   Pfam (4)   
All databases (25)   

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