KEGG T00220: TTHA1535

Thermus thermophilus HB8: TTHA1535

Entry

TTHA1535 CDS T00220

Definition

isocitrate dehydrogenase (EC:1.1.1.41)

Orthology

K00031

isocitrate dehydrogenase [EC:1.1.1.42]

Organism

ttj Thermus thermophilus HB8

Pathway

ttj00020	Citrate cycle (TCA cycle)
ttj00480	Glutathione metabolism
ttj01100	Metabolic pathways
ttj01110	Biosynthesis of secondary metabolites
ttj01120	Microbial metabolism in diverse environments
ttj01210	2-Oxocarboxylic acid metabolism
ttj01230	Biosynthesis of amino acids

Module

ttj_M00009	Citrate cycle (TCA cycle, Krebs cycle)
ttj_M00010	Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate

Class

Metabolism; Carbohydrate metabolism; Citrate cycle (TCA cycle) [PATH:ttj00020]
Metabolism; Metabolism of other amino acids; Glutathione metabolism [PATH:ttj00480]

SSDB

Motif

Pfam:

Iso_dh

Other DBs

NCBI-GI:

55981504

NCBI-GeneID:

3168917

UniProt:

P33197

Structure

PDB:

2D1C

Position

complement(1460972..1462462)

AA seq 496 aa
MPLITTETGKKMHVLEDGRKLITVIPGDGIGPECVEATLKVLEAAKAPLAYEVREAGASV
FRRGIASGVPQETIESIRKTRVVLKGPLETPVGYGEKSANVTLRKLFETYANVRPVREFP
NVPTPYAGRGIDLVVVRENVEDLYAGIEHMQTPSVAQTLKLISWKGSEKIVRFAFELARA
EGRKKVHCATKSNIMKLAEGTLKRAFEQVAQEYPDIEAVHIIVDNAAHQLVKRPEQFEVI
VTTNMNGDILSDLTSGLIGGLGFAPSANIGNEVAIFEAVHGSAPKYAGKNVINPTAVLLS
AVMMLRYLEEFATADLIENALLYTLEEGRVLTGDVVGYDRGAKTTEYTEAIIQNLGKTPR
KTQVRGYKPFRLPQVDGAIAPIVPRSRRVVGVDVFVETNLLPEALGKALEDLAAGTPFRL
KMISNRGTQVYPPTGGLTDLVDHYRCRFLYTGEGEAKDPEILDLVSRVASRFRWMHLEKL
QEFDGEPGFTKAQGED

NT seq 1491 nt +upstreamnt +downstreamnt
atgcccctgatcaccacggaaaccggcaagaagatgcacgttctcgaggacgggcgcaag
ctcatcaccgtcatccccggagacggcatcgggcccgagtgcgtggaggctaccctcaag
gtcctagaggcggccaaggcccccctggcctacgaggtgcgagaggcgggggcgagcgtc
ttccggcggggcatcgcctcgggcgttccccaggagaccattgagtccatccgcaagacc
cgggtggtcctgaagggtcccctggaaaccccggtgggctacggggagaagagcgccaac
gtcaccctaaggaagctctttgagacctacgccaacgtccgccccgtgcgggagttcccc
aacgtccccaccccctatgcgggccggggcattgacctcgtggtggtgcgggagaacgtg
gaggacctctacgccgggattgagcacatgcagaccccgagcgtggcccagaccctcaag
ctcatctcctggaagggatcggagaagatcgtccgcttcgcctttgagctggcccgggcc
gaggggcggaagaaggtccactgcgccaccaagtccaacatcatgaagctcgccgaaggg
accctgaagcgggcctttgagcaggtggcccaggagtaccccgacatagaagcggtccac
atcatcgtggacaacgctgcccaccagctggtgaaaaggcccgagcagtttgaggtgatc
gtcaccaccaacatgaacggagacatcctctccgacctcacctcggggctcattgggggc
ctgggcttcgctccctcggccaacatcggcaacgaggtggccatctttgaggccgtccac
ggttccgcccccaagtacgccgggaagaacgtcatcaaccccaccgcggtcctcctctcg
gcggtgatgatgctccgctacctggaggagttcgccacggcggaccttatagagaacgcc
ctcctctacaccctcgaggagggccgggtcctcacgggggacgtggtgggctacgaccgg
ggggccaagaccacggagtacaccgaggccatcatccagaacctgggcaagaccccaagg
aagacccaggtgcggggctacaagcccttccgcctgccccaggtggacggggccatcgcc
cccatcgtccctaggagccgccgggttgtgggggtggacgtcttcgtggaaaccaacctc
ctgcccgaggccctgggaaaggccctggaggaccttgccgcgggcacccccttccggctc
aagatgatctccaaccggggcacccaggtctacccccccaccggcgggctcacggacctg
gtggaccactaccgctgccgcttcctctacacgggggagggggaggctaaggacccggag
atcctggacctcgtaagccgggtggcaagccgcttccgctggatgcacctggagaagctc
caggaatttgacggcgagcccggcttcaccaaggcccaaggggaagactaa

All links

Pathway (9)   
   KEGG PATHWAY (7)   
   KEGG MODULE (2)   
Chemical substance (7)   
   KEGG COMPOUND (7)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
3D Structure (1)   
   PDB (1)   
Protein domain (1)   
   Pfam (1)   
All databases (29)   

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