KEGG   Tupaia chinensis (Chinese tree shrew): 102472442Help
Entry
102472442         CDS       T02978                                 

Definition
phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform-like
Orthology
K00922  
phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
Organism
tup  Tupaia chinensis (Chinese tree shrew)
Pathway
Inositol phosphate metabolism
ErbB signaling pathway
Ras signaling pathway
Rap1 signaling pathway
cGMP-PKG signaling pathway
Chemokine signaling pathway
HIF-1 signaling pathway
FoxO signaling pathway
Phosphatidylinositol signaling system
mTOR signaling pathway
PI3K-Akt signaling pathway
AMPK signaling pathway
Apoptosis
Adrenergic signaling in cardiomyocytes
VEGF signaling pathway
Osteoclast differentiation
Focal adhesion
Platelet activation
Toll-like receptor signaling pathway
Jak-STAT signaling pathway
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
B cell receptor signaling pathway
Fc epsilon RI signaling pathway
Fc gamma R-mediated phagocytosis
TNF signaling pathway
Leukocyte transendothelial migration
Neurotrophin signaling pathway
Cholinergic synapse
Inflammatory mediator regulation of TRP channels
Regulation of actin cytoskeleton
Insulin signaling pathway
Progesterone-mediated oocyte maturation
Estrogen signaling pathway
Prolactin signaling pathway
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Type II diabetes mellitus
Non-alcoholic fatty liver disease (NAFLD)
Aldosterone-regulated sodium reabsorption
Carbohydrate digestion and absorption
Bacterial invasion of epithelial cells
Chagas disease (American trypanosomiasis)
Toxoplasmosis
Amoebiasis
Hepatitis C
Hepatitis B
Measles
Influenza A
HTLV-I infection
Epstein-Barr virus infection
Pathways in cancer
Viral carcinogenesis
Proteoglycans in cancer
Colorectal cancer
Renal cell carcinoma
Pancreatic cancer
Endometrial cancer
Glioma
Prostate cancer
Melanoma
Chronic myeloid leukemia
Acute myeloid leukemia
Small cell lung cancer
Non-small cell lung cancer
Brite
KEGG Orthology (KO) [BR:tup00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    102472442
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    102472442
   04015 Rap1 signaling pathway
    102472442
   04012 ErbB signaling pathway
    102472442
   04370 VEGF signaling pathway
    102472442
   04630 Jak-STAT signaling pathway
    102472442
   04668 TNF signaling pathway
    102472442
   04066 HIF-1 signaling pathway
    102472442
   04068 FoxO signaling pathway
    102472442
   04070 Phosphatidylinositol signaling system
    102472442
   04022 cGMP - PKG signaling pathway
    102472442
   04151 PI3K-Akt signaling pathway
    102472442
   04152 AMPK signaling pathway
    102472442
   04150 mTOR signaling pathway
    102472442
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    102472442
  Cell growth and death
   04210 Apoptosis
    102472442
  Cell communication
   04510 Focal adhesion
    102472442
 Organismal Systems
  Immune system
   04611 Platelet activation
    102472442
   04620 Toll-like receptor signaling pathway
    102472442
   04650 Natural killer cell mediated cytotoxicity
    102472442
   04660 T cell receptor signaling pathway
    102472442
   04662 B cell receptor signaling pathway
    102472442
   04664 Fc epsilon RI signaling pathway
    102472442
   04666 Fc gamma R-mediated phagocytosis
    102472442
   04670 Leukocyte transendothelial migration
    102472442
   04062 Chemokine signaling pathway
    102472442
  Endocrine system
   04910 Insulin signaling pathway
    102472442
   04915 Estrogen signaling pathway
    102472442
   04914 Progesterone-mediated oocyte maturation
    102472442
   04917 Prolactin signaling pathway
    102472442
   04921 Oxytocin signaling pathway
    102472442
   04919 Thyroid hormone signaling pathway
    102472442
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    102472442
  Digestive system
   04973 Carbohydrate digestion and absorption
    102472442
  Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    102472442
  Nervous system
   04725 Cholinergic synapse
    102472442
   04722 Neurotrophin signaling pathway
    102472442
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    102472442
  Development
   04380 Osteoclast differentiation
    102472442
 Human Diseases
  Cancers
   05200 Pathways in cancer
    102472442
   05205 Proteoglycans in cancer
    102472442
   05203 Viral carcinogenesis
    102472442
   05210 Colorectal cancer
    102472442
   05212 Pancreatic cancer
    102472442
   05214 Glioma
    102472442
   05221 Acute myeloid leukemia
    102472442
   05220 Chronic myeloid leukemia
    102472442
   05218 Melanoma
    102472442
   05211 Renal cell carcinoma
    102472442
   05215 Prostate cancer
    102472442
   05213 Endometrial cancer
    102472442
   05222 Small cell lung cancer
    102472442
   05223 Non-small cell lung cancer
    102472442
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    102472442
   04932 Non-alcoholic fatty liver disease (NAFLD)
    102472442
  Infectious diseases
   05100 Bacterial invasion of epithelial cells
    102472442
   05166 HTLV-I infection
    102472442
   05162 Measles
    102472442
   05164 Influenza A
    102472442
   05161 Hepatitis B
    102472442
   05160 Hepatitis C
    102472442
   05169 Epstein-Barr virus infection
    102472442
   05146 Amoebiasis
    102472442
   05145 Toxoplasmosis
    102472442
   05142 Chagas disease (American trypanosomiasis)
    102472442
Enzymes [BR:tup01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     102472442
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Position
Un
AA seq 1118 aa AA seqDB search
MDIHKVPATVLQVTWGMELEKYEQPVVLREDNRRRRRRMKQRSAAASLSSMELIPIEFVL
PTSQRNSKTPETALLHVAGHGNVEQMKAQVWLRALETSVAADFYHRLGPDHFLLLYQKKG
QWYEIYDKYQVVQTLDCLRYWKALHRSPGQIHVVQRHAPSEETLAFQRQLTALIGYDVTD
ISNVHDDELEFTRRRLVTPRMAEVAGRDPMLYAMHPWVTSKPLPEYLSKKISNNCIFIII
HRSTTSQTIKVSADDTPATILQSFFTKMAKKKSLMDIPESQNEQDFVLRVCGRDEYLVGE
TPIKNFQWVRHCLKNGEEIHLVLDRAPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGK
DHESVFTVSLWDCDRKFRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPF
TEEVLWNVWLEFSIKIRDLPKGALLNLQIFCGKSPALSGKASAETPSSESKGKVQLLYYV
NLLLIDHRFLLRHGEYVLHMWQISGKGEDQGSFSADKLTSATNPDKENSMSISILLDNYC
HPIALPKHRPTPDPEGDRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLK
HPKAYPKLFSSVKWGQQEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIA
VQKLESLEDDDVLHYLLQLVQAVKFEPYHDSALVRFLLKRGLRNKRIGHFLFWFLRSEIA
QSRHYQQRFAVILEAYLRGCGTAMLHDFTQQVQVIEMLQKVTIDIKSLSAEKYDVSSQVI
SQLKQKLENLQNSNLPESFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFRCADPTALS
NETIGIIFKHGDDLRQDMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKD
ATTIAKIQQSTVGNTGAFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGI
GDRHNDNIMITETGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSP
YFQKFQDVCVKAYLALRHHTNLLIILFSMMLMTGIPQLTSKEDIEYIRDALTVGRNEEDA
KKYFLDQIEVCRDKGWTVQFNWFLHLVLGIKQGEKHSA
NT seq 3357 nt NT seq  +upstreamnt  +downstreamnt
atggatatccacaaggttccggcaacagttctgcaggtcacgtggggcatggagctggag
aaatatgaacagccggtggttctgagagaggacaatcgccgcaggcgccggaggatgaag
cagcgnagtgccgcggccagcctgtcctccatggagctcatccccatcgagttcgtgctg
cccaccagccagcgcaacagcaagactccggaaacagcgctgctgcacgtggcgggccac
ggcaacgtggagcagatgaaggcccaggtgtggctgcgcgcgctggagaccagcgtggca
gcggacttctatcaccggcttgggccggaccacttcctcctgctctaccaaaagaagggg
cagtggtacgagatctacgacaagtaccaagtggtgcagaccctggactgcctgcgctac
tggaaggcactgcatcggagcccgggccagatccacgtggtgcaacggcacgcgccctcg
gaggagactctggccttccagaggcagctcactgctcttattggctacgacgtcactgac
atcagcaacgtgcacgacgacgagctagagttcacccggcgccgcctagtcaccccacgc
atggcggaggtcgctggtcgtgaccccatgctctatgccatgcacccctgggtgacatca
aagccccttccagagtacctgtccaagaagattagcaacaattgcatcttcatcatcatt
caccgcagcaccaccagccagaccatcaaggtctcagccgatgacacccctgccaccatc
ctccagagcttcttcaccaagatggccaagaagaagtctctgatggacatccctgaaagc
cagaatgaacaggattttgtgctgcgcgtttgtggccgggatgaatacctggtgggtgaa
acacccatcaaaaacttccagtgggtgaggcactgcctcaagaatggggaagagattcac
ctggtgcttgacagagctccagacccagccctggatgaggtgaggaaagaagagtggccg
ctagtggatgactgcacgggagtcaccggttaccatgagcagttgactatccacggcaag
gaccacgagagcgtattcaccgtgtccctgtgggactgtgaccggaagttcagggtcaag
atcagaggcattgatatccctgtcctgccccggaacacagacctcacagtttttgtggaa
gcgaacatccagcatgggcagcaagttctttgccaaaggagaaccagccccaaacccttc
acggaggaggtgctctggaatgtgtggctggagttcagtatcaaaatcagggacttaccc
aaaggggctctactgaacctgcagattttctgtggcaaatctccagcattgtctggcaag
gcctctgcggagactcctagttcagagtccaaaggcaaagtgcaactcctctactacgtg
aacctgctgctgatagaccaccggttcctcctgcgccatggggaatatgtgctccacatg
tggcagatatccgggaagggggaagaccaagggagtttcagtgccgataagctcacatct
gccaccaacccagacaaggagaactcaatgtccatctccattcttctggacaattactgt
caccccatagccctacccaagcatcggcccactcctgacccagaaggggatcgtgttcga
gctgaaatgcccaaccagcttcgcaagcaactagaggcaatcatagccactgatccactt
aatcctctcactgctgaggacaaagaattactctggcattttagatatgaaagcctcaag
catcctaaagcatatcctaagctatttagctcagtgaaatggggacagcaagaaattgtg
gccaaaacataccaattgttagccagaagggaggtctgggatcaaagtgctttggatgtt
gggttaacaatgcaactcttggactgcaacttttcggatgaaaatgtgagagccatcgca
gttcagaaactggagagcttggaagacgatgacgttctacattaccttctacagctggtt
caggctgtgaaatttgaaccataccatgacagtgccctcgtcagatttctactgaagcgt
ggcttaagaaacaaaagaattggacactttttgttttggttcttgagaagtgagattgcc
cagtccagacactatcagcagaggtttgcggtgatcctggaagcctatcttaggggctgt
ggcacagccatgctgcacgacttcacccaacaagttcaagtcattgagatgttacagaag
gtcaccatcgatattaaatcactatctgctgaaaagtatgacgtcagttcccaagttatt
tcacagcttaagcaaaagcttgaaaatctgcagaattctaatcttccagaaagctttaga
gttccatatgaccctggactgaaagcaggagcactggtgattgaaaaatgtaaagtgatg
gcctccaagaaaaagcccctgtggcttgagtttagatgtgccgatcctacagcgctatca
aacgaaacgattggaattatctttaaacatggtgatgatctgcgccaagacatgcttatt
ttacagattctacgaattatggagtccatttgggagactgaatctttggatctgtgcctc
ttgccatatggttgcatttcaactggtgacaagattggaatgatcgagatcgtgaaagat
gccacgacaattgccaaaattcagcaaagtacggtaggcaacactggtgcgtttaaagat
gaagtcctgaatcactggctaaaagaaaaatgccctatcgaagaaaagtttcaggcagca
gtggagagatttgtttattcctgtgcaggctactgtgtggcaacctttgttcttggaata
ggtgacagacacaacgacaatattatgatcacagagacaggaaacctattccatattgat
tttgggcacattcttgggaattacaaaagtttcctgggcattaataaagagagagtgcca
ttcgtgctaaccccagacttcctgtttgtgatgggaacttctggaaagaagacaagccca
tacttccagaaatttcaggatgtctgtgttaaggcttatctagcccttcgtcatcacaca
aatctactgatcatcctattctccatgatgctgatgacaggaattccccagttaacaagc
aaagaagatatcgaatatattcgggatgccctaacagtggggcgaaatgaggaggatgct
aagaagtatttccttgatcaaattgaagtgtgcagagacaaaggatggaccgtgcaattt
aactggttcctacatctggttcttggcatcaaacaaggagagaaacattcagcctaa

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