KEGG   Tupaia chinensis (Chinese tree shrew): 102487565
Entry
102487565         CDS       T02978                                 
Name
(RefSeq) cholesterol side-chain cleavage enzyme, mitochondrial-like
  KO
K00498  cholesterol monooxygenase (side-chain-cleaving) [EC:1.14.15.6]
Organism
tup  Tupaia chinensis (Chinese tree shrew)
Pathway
tup00140  Steroid hormone biosynthesis
tup01100  Metabolic pathways
tup04913  Ovarian steroidogenesis
tup04925  Aldosterone synthesis and secretion
tup04927  Cortisol synthesis and secretion
tup04934  Cushing syndrome
Module
tup_M00107  Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone
Brite
KEGG Orthology (KO) [BR:tup00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    102487565
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    102487565
   04925 Aldosterone synthesis and secretion
    102487565
   04927 Cortisol synthesis and secretion
    102487565
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    102487565
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:tup00199]
    102487565
Enzymes [BR:tup01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.15  With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.15.6  cholesterol monooxygenase (side-chain-cleaving)
     102487565
Cytochrome P450 [BR:tup00199]
 Cytochrome P450, animal type
  CYP11 family
   102487565
SSDB
Motif
Pfam: p450
Other DBs
NCBI-GeneID: 102487565
NCBI-ProteinID: XP_006153441
Position
Un
AA seq 347 aa
MALNPEVMSPESIRNFVPLLEAVAQDFINLIHRRIRQQGSGKFSGDISDDLFRFAFESIT
NVIFGERQGMLEEVVDPKAQQFIDAVYKMFHSSVPMLNLPPTLFRVLRTKAWRDHVASWD
VIFDRAEKYTQNFYWDLRQKRDVGANYPGILYRLLGSDKLPFEDIKANITEMLAGGVDTT
SVTLQWHLYEMGRNLRVQEMLRAEVLAARRQAQGNLTDMLQLVPLLRASIKETLRLHPIS
VTLQRYLVNDLVLRNYVIPAKTLVQVSNYAMGREPSIFFNPRNFDPTRWLSKDKNSIHFQ
SLGFGWGLRQCLGRRIVGTAFSLIRVPDKPIFLTFKPLDQEDLAPQA
NT seq 1044 nt   +upstreamnt  +downstreamnt
atggccctgaacccggaggtgatgtccccagagtccatcaggaacttcgtgcccctgcta
gaagcagtggcccaggacttcatcaacctcatacacaggcgcatccggcagcagggttct
ggaaagttctcaggggatatcagcgatgacctgttccgctttgccttcgagtccatcacc
aatgtcatttttggggagcgccaggggatgctggaggaggtagtggaccccaaggcccag
caattcatcgacgccgtctacaagatgtttcacagcagcgtgcccatgctcaacctgcct
cccaccctgttccgcgtgctccggaccaaggcctggagggaccatgtggcctcatgggat
gtgattttcgatagagctgaaaagtacacccagaacttctactgggacctgagacagaag
agagatgttggcgccaactacccgggcatcctgtacaggctcctgggaagtgacaagctg
ccttttgaggacatcaaggccaacatcaccgaaatgctggcaggaggtgtggacacgacg
tccgtgaccctgcagtggcacttgtacgagatggggcgcaacctgagggtacaggagatg
ctgcgtgcagaggttctggcggcccggcgccaggcccaggggaacctgaccgacatgctg
cagctggtcccgctcctcagagccagcatcaaggagacgctgaggctccaccctatctcc
gtgaccctgcagagatacctcgttaacgacttggttcttcgcaattacgtgattcctgcc
aagacattggtacaggtgtccaactatgccatgggccgagagcccagcatcttcttcaac
ccgaggaatttcgaccccactcgatggctaagcaaagacaagaacagcatccacttccag
agcctgggcttcggctgggggctgaggcagtgtctgggccggcggatcgtgggcaccgcg
ttcagcctcatccgggtgcccgacaagcccatcttcctgaccttcaagcccctggaccaa
gaagaccttgcaccccaggcatga

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