KEGG   Tupaia chinensis (Chinese tree shrew): 102500530Help
Entry
102500530         CDS       T02978                                 

Gene name
PIK3CD
Definition
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
Orthology
K00922  
phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
Organism
tup  Tupaia chinensis (Chinese tree shrew)
Pathway
Inositol phosphate metabolism
ErbB signaling pathway
Ras signaling pathway
Rap1 signaling pathway
cGMP-PKG signaling pathway
Chemokine signaling pathway
HIF-1 signaling pathway
FoxO signaling pathway
Phosphatidylinositol signaling system
mTOR signaling pathway
PI3K-Akt signaling pathway
AMPK signaling pathway
Apoptosis
Adrenergic signaling in cardiomyocytes
VEGF signaling pathway
Osteoclast differentiation
Focal adhesion
Platelet activation
Toll-like receptor signaling pathway
Jak-STAT signaling pathway
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
B cell receptor signaling pathway
Fc epsilon RI signaling pathway
Fc gamma R-mediated phagocytosis
TNF signaling pathway
Leukocyte transendothelial migration
Neurotrophin signaling pathway
Cholinergic synapse
Inflammatory mediator regulation of TRP channels
Regulation of actin cytoskeleton
Insulin signaling pathway
Progesterone-mediated oocyte maturation
Estrogen signaling pathway
Prolactin signaling pathway
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Type II diabetes mellitus
Non-alcoholic fatty liver disease (NAFLD)
Aldosterone-regulated sodium reabsorption
Carbohydrate digestion and absorption
Bacterial invasion of epithelial cells
Chagas disease (American trypanosomiasis)
Toxoplasmosis
Amoebiasis
Hepatitis C
Hepatitis B
Measles
Influenza A
HTLV-I infection
Epstein-Barr virus infection
Pathways in cancer
Viral carcinogenesis
Proteoglycans in cancer
Colorectal cancer
Renal cell carcinoma
Pancreatic cancer
Endometrial cancer
Glioma
Prostate cancer
Melanoma
Chronic myeloid leukemia
Acute myeloid leukemia
Small cell lung cancer
Non-small cell lung cancer
Brite
KEGG Orthology (KO) [BR:tup00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    102500530 (PIK3CD)
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    102500530 (PIK3CD)
   04015 Rap1 signaling pathway
    102500530 (PIK3CD)
   04012 ErbB signaling pathway
    102500530 (PIK3CD)
   04370 VEGF signaling pathway
    102500530 (PIK3CD)
   04630 Jak-STAT signaling pathway
    102500530 (PIK3CD)
   04668 TNF signaling pathway
    102500530 (PIK3CD)
   04066 HIF-1 signaling pathway
    102500530 (PIK3CD)
   04068 FoxO signaling pathway
    102500530 (PIK3CD)
   04070 Phosphatidylinositol signaling system
    102500530 (PIK3CD)
   04022 cGMP - PKG signaling pathway
    102500530 (PIK3CD)
   04151 PI3K-Akt signaling pathway
    102500530 (PIK3CD)
   04152 AMPK signaling pathway
    102500530 (PIK3CD)
   04150 mTOR signaling pathway
    102500530 (PIK3CD)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    102500530 (PIK3CD)
  Cell growth and death
   04210 Apoptosis
    102500530 (PIK3CD)
  Cell communication
   04510 Focal adhesion
    102500530 (PIK3CD)
 Organismal Systems
  Immune system
   04611 Platelet activation
    102500530 (PIK3CD)
   04620 Toll-like receptor signaling pathway
    102500530 (PIK3CD)
   04650 Natural killer cell mediated cytotoxicity
    102500530 (PIK3CD)
   04660 T cell receptor signaling pathway
    102500530 (PIK3CD)
   04662 B cell receptor signaling pathway
    102500530 (PIK3CD)
   04664 Fc epsilon RI signaling pathway
    102500530 (PIK3CD)
   04666 Fc gamma R-mediated phagocytosis
    102500530 (PIK3CD)
   04670 Leukocyte transendothelial migration
    102500530 (PIK3CD)
   04062 Chemokine signaling pathway
    102500530 (PIK3CD)
  Endocrine system
   04910 Insulin signaling pathway
    102500530 (PIK3CD)
   04915 Estrogen signaling pathway
    102500530 (PIK3CD)
   04914 Progesterone-mediated oocyte maturation
    102500530 (PIK3CD)
   04917 Prolactin signaling pathway
    102500530 (PIK3CD)
   04921 Oxytocin signaling pathway
    102500530 (PIK3CD)
   04919 Thyroid hormone signaling pathway
    102500530 (PIK3CD)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    102500530 (PIK3CD)
  Digestive system
   04973 Carbohydrate digestion and absorption
    102500530 (PIK3CD)
  Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    102500530 (PIK3CD)
  Nervous system
   04725 Cholinergic synapse
    102500530 (PIK3CD)
   04722 Neurotrophin signaling pathway
    102500530 (PIK3CD)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    102500530 (PIK3CD)
  Development
   04380 Osteoclast differentiation
    102500530 (PIK3CD)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    102500530 (PIK3CD)
   05205 Proteoglycans in cancer
    102500530 (PIK3CD)
   05203 Viral carcinogenesis
    102500530 (PIK3CD)
   05210 Colorectal cancer
    102500530 (PIK3CD)
   05212 Pancreatic cancer
    102500530 (PIK3CD)
   05214 Glioma
    102500530 (PIK3CD)
   05221 Acute myeloid leukemia
    102500530 (PIK3CD)
   05220 Chronic myeloid leukemia
    102500530 (PIK3CD)
   05218 Melanoma
    102500530 (PIK3CD)
   05211 Renal cell carcinoma
    102500530 (PIK3CD)
   05215 Prostate cancer
    102500530 (PIK3CD)
   05213 Endometrial cancer
    102500530 (PIK3CD)
   05222 Small cell lung cancer
    102500530 (PIK3CD)
   05223 Non-small cell lung cancer
    102500530 (PIK3CD)
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    102500530 (PIK3CD)
   04932 Non-alcoholic fatty liver disease (NAFLD)
    102500530 (PIK3CD)
  Infectious diseases
   05100 Bacterial invasion of epithelial cells
    102500530 (PIK3CD)
   05166 HTLV-I infection
    102500530 (PIK3CD)
   05162 Measles
    102500530 (PIK3CD)
   05164 Influenza A
    102500530 (PIK3CD)
   05161 Hepatitis B
    102500530 (PIK3CD)
   05160 Hepatitis C
    102500530 (PIK3CD)
   05169 Epstein-Barr virus infection
    102500530 (PIK3CD)
   05146 Amoebiasis
    102500530 (PIK3CD)
   05145 Toxoplasmosis
    102500530 (PIK3CD)
   05142 Chagas disease (American trypanosomiasis)
    102500530 (PIK3CD)
Enzymes [BR:tup01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     102500530 (PIK3CD)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Position
Un
AA seq 1044 aa AA seqDB search
MPPGVDCPMEFWTKEENQNVAVDFLLPTGIYLNFPVSRNANLSTIKQVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRAKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSAPSLRA
STLRGPNRALLVNVKFEGSEESFTFQVSTKDMPLALMACALRKKATVFRQPLLEQPEDYT
LQVNGRHEYLYGSYPLCQFQYICSCLHSGQTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPVPVKKLSSVSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
CEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKTRKARATKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPTGTVRSNPNTESAAALVICLPEVAP
HPVYYPALEKILELGRPGERGRFTEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKELMHLCMR
QETYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWIMYSNEEAGSDGSVGIIFKN
GDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLPTGDRTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGDTLDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
NT seq 3135 nt NT seq  +upstreamnt  +downstreamnt
atgccccctggggttgactgccccatggaattctggaccaaggaggagaatcagaacgtg
gcggttgacttcctgctgcccacagggatctacctgaacttccccgtgtcccgcaatgcc
aacctcagcaccatcaagcaggtgctgtggcaccgcgcccagtatgagccgctgttccac
atgctcagcgaccccgaggcctacgtgttcacctgcgtcaaccagacggcggagcagcag
gagctggaggacgagcagcggcggctgtgcgatgtgcagcccttcctgccggtgctgcgc
ctggtggcccgcgagggtgaccgtgtgaagaagctcatcaactcccagatcagcctcctc
atcggcaaaggcctccacgaatttgactccttgcgcgaccccgaggtgaacgacttccgt
gccaagatgcgccagttctgcgaggaggcggcggcccgccggcagcagctgggctgggag
gcctggctgcagtacagcttccccctgcagctggagccctcagcacccagcctgagggcc
agcaccctgcggggccccaaccgcgccctcctggtcaatgtcaagtttgaaggcagtgag
gagagcttcaccttccaggtgtccaccaaggacatgcccctggcactgatggcctgcgcc
ctccggaagaaggccacggtattccggcagcccctgctggagcagcccgaggactacacg
ctgcaagtgaatgggaggcatgagtacctctacggcagctaccccctctgccagttccag
tacatctgcagctgcctgcacagcgggcagacccctcacctgaccatggtccactcctcc
tccatcctcgccatgcgggacgagcagagcaaccctgccccccaagtccagaaacctcgc
accaaaccgccccctgttcccgtaaagaagctgtcctccgtgtccctgtggtccctggag
cagccgttctgcatcgagctgatccagggcagcaaagtgaacgcagacgagcggatgaag
ctggtggtgcaggctgggctgttccatggcaacgagatgctgtgcaagacggtgtccagt
tgcgaggtcagcgtgtgctcggagcccgtgtggaagcagcggctggagttcgacatcaac
atctgtgacctgcctcgcatggcccggctctgcttcgccctctatgccgtcatcgagaag
accaggaaggctcgtgccaccaaaaagaagtccaagaaggcggactgccccatcgcctgg
gccaacctcatgctgtttgactacaaggaccagctcaagaccggggagcgctgcctctac
atgtggccgtccgtcccagatgagaaaggggagctactgaaccccacgggtactgtgcgc
agtaaccccaacacggagagtgctgccgccctggtcatctgcctgcccgaggtggccccc
caccccgtgtactaccctgccctggagaagatcctagagctggggcggcccggagagcgc
gggcgcttcactgaggaggagcaactgcagctgagggaaatcctggagcggcgggggtct
ggggagctatatgagcacgagaaggacctggtgtggaagatgcggcatgaagtccaggag
cacttcccggaggcgctggcccgactgctgctggtcactaagtggaacaagcatgaggat
gtggcccagatgctctacctgttgtgctcctggcccgagctgcccgtcctgagcgccctg
gagctgctggacttcagcttccccgactgccacgtgggctccttcgccatcaagtccctg
cggaaactgacggacgacgagcttttccagtacctgctgcagctggtgcaggttctcaag
tacgagtcctacttggactgcgagctgaccaaattcttgctggaccgggccctggccaac
cgcaagatcggccacttcctcttctggcacctccgctctgagatgcacgtcccgtcagtg
gccctgcgctttggcctcatcatggaggcctattgcaggggcagcacccaccacatgaaa
gtgctgatgaagcagggggaagcactgagcaaactgaaggccctgaacgacttcgtcaag
gtcagctcccagaagaccaccaagccccagaccaaggagctgatgcacctatgcatgcgc
caggagacctacctggaggccctctcccacctgcagtcccccctcgaccccagcaccctg
ctggctgaagtctgtgtggagcagtgcaccttcatggactccaagatgaagccgctgtgg
atcatgtacagcaacgaggaggcgggcagtgatggcagcgtgggcatcatcttcaagaac
ggggatgacctgcgccaggacatgctgactctgcagatgatccagctcatggacatcctg
tggaagcaggagggcctggacctcaggatgaccccctatggctgcctccccactggagac
cgcacgggcctcattgaagtggtgcttcactcagacaccatcgccaacatccagctgaac
aagagcaacatggcggccacagccgccttcaacaaggatgccctgctcaactggctcaag
tccaagaaccctggcgacaccctggaccgagccattgaggagttcaccctttcctgtgct
ggctactgtgtggccacgtacgtgctgggcatcggcgaccggcacagcgacaacatcatg
atccgcgagagcgggcagctgttccacattgattttggccacttcctggggaatttcaag
accaagtttggaatcaaccgtgagcgagtgcccttcatcctcacctatgactttgtccat
gtgattcagcagggaaagacgaataatagtgagaaatttgaaaggttccggggctactgt
gagagagcctacaccatcctgcggcgccacgggctgctcttcctccacctctttgccctg
atgcgggcggcaggcctgcctgagctcagctgctccaaagacatccagtatctcaaggac
tctctggcactgggaaagacggaggaggaggctctgaagcacttccgagtgaagttcaac
gaagccctccgggagagctggaaaaccaaagtgaactggctggcccacaacgtgtccaaa
gataacaggcaatag

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