KEGG   Tupaia chinensis (Chinese tree shrew): 102502163Help
Entry
102502163         CDS       T02978                                 

Gene name
PIK3CB
Definition
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
Orthology
K00922  
phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
Organism
tup  Tupaia chinensis (Chinese tree shrew)
Pathway
Inositol phosphate metabolism
ErbB signaling pathway
Ras signaling pathway
Rap1 signaling pathway
cGMP-PKG signaling pathway
cAMP signaling pathway
Chemokine signaling pathway
HIF-1 signaling pathway
FoxO signaling pathway
Phosphatidylinositol signaling system
mTOR signaling pathway
PI3K-Akt signaling pathway
AMPK signaling pathway
Apoptosis
Adrenergic signaling in cardiomyocytes
VEGF signaling pathway
Osteoclast differentiation
Focal adhesion
Platelet activation
Toll-like receptor signaling pathway
Jak-STAT signaling pathway
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
B cell receptor signaling pathway
Fc epsilon RI signaling pathway
Fc gamma R-mediated phagocytosis
TNF signaling pathway
Leukocyte transendothelial migration
Neurotrophin signaling pathway
Cholinergic synapse
Inflammatory mediator regulation of TRP channels
Regulation of actin cytoskeleton
Insulin signaling pathway
Progesterone-mediated oocyte maturation
Estrogen signaling pathway
Prolactin signaling pathway
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Type II diabetes mellitus
Non-alcoholic fatty liver disease (NAFLD)
Aldosterone-regulated sodium reabsorption
Carbohydrate digestion and absorption
Bacterial invasion of epithelial cells
Chagas disease (American trypanosomiasis)
Toxoplasmosis
Amoebiasis
Hepatitis C
Hepatitis B
Measles
Influenza A
HTLV-I infection
Epstein-Barr virus infection
Pathways in cancer
Viral carcinogenesis
Proteoglycans in cancer
Colorectal cancer
Renal cell carcinoma
Pancreatic cancer
Endometrial cancer
Glioma
Prostate cancer
Melanoma
Chronic myeloid leukemia
Acute myeloid leukemia
Small cell lung cancer
Non-small cell lung cancer
Brite
KEGG Orthology (KO) [BR:tup00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    102502163 (PIK3CB)
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    102502163 (PIK3CB)
   04015 Rap1 signaling pathway
    102502163 (PIK3CB)
   04012 ErbB signaling pathway
    102502163 (PIK3CB)
   04370 VEGF signaling pathway
    102502163 (PIK3CB)
   04630 Jak-STAT signaling pathway
    102502163 (PIK3CB)
   04668 TNF signaling pathway
    102502163 (PIK3CB)
   04066 HIF-1 signaling pathway
    102502163 (PIK3CB)
   04068 FoxO signaling pathway
    102502163 (PIK3CB)
   04070 Phosphatidylinositol signaling system
    102502163 (PIK3CB)
   04024 cAMP signaling pathway
    102502163 (PIK3CB)
   04022 cGMP - PKG signaling pathway
    102502163 (PIK3CB)
   04151 PI3K-Akt signaling pathway
    102502163 (PIK3CB)
   04152 AMPK signaling pathway
    102502163 (PIK3CB)
   04150 mTOR signaling pathway
    102502163 (PIK3CB)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    102502163 (PIK3CB)
  Cell growth and death
   04210 Apoptosis
    102502163 (PIK3CB)
  Cell communication
   04510 Focal adhesion
    102502163 (PIK3CB)
 Organismal Systems
  Immune system
   04611 Platelet activation
    102502163 (PIK3CB)
   04620 Toll-like receptor signaling pathway
    102502163 (PIK3CB)
   04650 Natural killer cell mediated cytotoxicity
    102502163 (PIK3CB)
   04660 T cell receptor signaling pathway
    102502163 (PIK3CB)
   04662 B cell receptor signaling pathway
    102502163 (PIK3CB)
   04664 Fc epsilon RI signaling pathway
    102502163 (PIK3CB)
   04666 Fc gamma R-mediated phagocytosis
    102502163 (PIK3CB)
   04670 Leukocyte transendothelial migration
    102502163 (PIK3CB)
   04062 Chemokine signaling pathway
    102502163 (PIK3CB)
  Endocrine system
   04910 Insulin signaling pathway
    102502163 (PIK3CB)
   04915 Estrogen signaling pathway
    102502163 (PIK3CB)
   04914 Progesterone-mediated oocyte maturation
    102502163 (PIK3CB)
   04917 Prolactin signaling pathway
    102502163 (PIK3CB)
   04921 Oxytocin signaling pathway
    102502163 (PIK3CB)
   04919 Thyroid hormone signaling pathway
    102502163 (PIK3CB)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    102502163 (PIK3CB)
  Digestive system
   04973 Carbohydrate digestion and absorption
    102502163 (PIK3CB)
  Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    102502163 (PIK3CB)
  Nervous system
   04725 Cholinergic synapse
    102502163 (PIK3CB)
   04722 Neurotrophin signaling pathway
    102502163 (PIK3CB)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    102502163 (PIK3CB)
  Development
   04380 Osteoclast differentiation
    102502163 (PIK3CB)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    102502163 (PIK3CB)
   05205 Proteoglycans in cancer
    102502163 (PIK3CB)
   05203 Viral carcinogenesis
    102502163 (PIK3CB)
   05210 Colorectal cancer
    102502163 (PIK3CB)
   05212 Pancreatic cancer
    102502163 (PIK3CB)
   05214 Glioma
    102502163 (PIK3CB)
   05221 Acute myeloid leukemia
    102502163 (PIK3CB)
   05220 Chronic myeloid leukemia
    102502163 (PIK3CB)
   05218 Melanoma
    102502163 (PIK3CB)
   05211 Renal cell carcinoma
    102502163 (PIK3CB)
   05215 Prostate cancer
    102502163 (PIK3CB)
   05213 Endometrial cancer
    102502163 (PIK3CB)
   05222 Small cell lung cancer
    102502163 (PIK3CB)
   05223 Non-small cell lung cancer
    102502163 (PIK3CB)
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    102502163 (PIK3CB)
   04932 Non-alcoholic fatty liver disease (NAFLD)
    102502163 (PIK3CB)
  Infectious diseases
   05100 Bacterial invasion of epithelial cells
    102502163 (PIK3CB)
   05166 HTLV-I infection
    102502163 (PIK3CB)
   05162 Measles
    102502163 (PIK3CB)
   05164 Influenza A
    102502163 (PIK3CB)
   05161 Hepatitis B
    102502163 (PIK3CB)
   05160 Hepatitis C
    102502163 (PIK3CB)
   05169 Epstein-Barr virus infection
    102502163 (PIK3CB)
   05146 Amoebiasis
    102502163 (PIK3CB)
   05145 Toxoplasmosis
    102502163 (PIK3CB)
   05142 Chagas disease (American trypanosomiasis)
    102502163 (PIK3CB)
Enzymes [BR:tup01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     102502163 (PIK3CB)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Position
Un
AA seq 1064 aa AA seqDB search
MPPAMADVLDIWAVDSQIASDGSIPVDFLLPTGIYIQMEVPREATISYIKQMLWKQVHNY
PMFNLLMEVDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGEKLDSKI
GVLIGKGLHEFDALKDPEVNEFRRKMRKFSEEKIQSLVGLSWMDWLKQTYPPEHEPSVLE
NLEDKLYGGKLIVAVHFENSQDVFSFQVSPNMSPIKVNELAIQKRLTIHGKEDEASPCDY
VLQVSGRVEYVFGDHPLIQFQYVRNCVMSRTLPHFILVECCKIKKMYEQEMLAIEGAIQR
SSSTPPLPLPPKKTRIISHIWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHGTELLCK
TIVSSEISGKNDHVWNEPLEFDINICDLPRMARLCFAVYAVLDKVKTKKSTKTINPSKYQ
TIRKAGKVHYPVAWVNTMVFDFKGQLRSGDVILHSWSSFPDELEEMLNPMGTVQTNPYTE
NATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKEILDRDP
LSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPKLPPREA
LELLDFNYPDQYVREYAVECLQQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALA
NRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLKTLNSLI
KLNAMKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVILSELYVEKCKYMDSKMKPL
WLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATGD
RSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEEFTLSCA
GYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIH
VIQQGKTGNTEKFGRFRQCCEDAYLVLRRHGNLFITLFALMLTAGLPELTSVKDIQYLKD
SLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
NT seq 3195 nt NT seq  +upstreamnt  +downstreamnt
atgcctcctgctatggcggacgtccttgacatctgggccgtggactcgcagatcgcgtcc
gatggctccatccccgtggatttcctcttgcccactgggatctacattcagatggaggtg
cctcgggaagcgaccatttcttacattaagcagatgttatggaagcaagttcacaattac
cccatgtttaacctccttatggaagtggactcctacatgttcgcgtgtgtgaaccagacc
gccgtgtatgaggagctcgaagatgaaacacggagactctgcgacgtcaggcctttcctg
ccggtcctcaaattagtgacaagaagctgcgacccaggggaaaaactagattcaaaaatc
ggagttctcataggaaaaggtctgcatgaatttgatgccttgaaggatccagaagtgaat
gaatttcgaaggaaaatgcgcaaattcagcgaggaaaagattcagtcgctggttggattg
tcttggatggactggctgaagcagacatacccacccgagcatgagccgtctgtccttgaa
aacttagaagataaactttatggagggaagctcatcgtggctgttcattttgaaaatagt
caggatgtgtttagctttcaagtatctcctaacatgagccctatcaaagtaaatgagctc
gcgatccagaaacgcttgactattcacgggaaggaggacgaggcgagcccctgtgactat
gtgctgcaggtcagtgggagagtggagtacgtgttcggcgatcacccgctgatccagttc
cagtacgtccggaactgcgtaatgagcaggacgctgccccatttcattcttgtggagtgc
tgtaagattaagaagatgtacgagcaggagatgttggccatagaaggtgccatacagcgg
agctcgtccacccctcctctccccttgccgccaaagaaaacgcgaattatttctcacatc
tgggagaataacaaccctttccaaatcgttctggttaagggcaataaactgaacacagaa
gaaactgtaaaggttcatgtcagagctggtctttttcacggtactgagctcttgtgtaaa
accatcgtgagctcagagatatcaggaaagaacgaccacgtttggaacgagccgctggag
ttcgatattaacatatgtgacttgccgaggatggcacggttatgtttcgctgtttacgcg
gttttggataaagtgaagacgaagaaatcaactaaaactattaatccctctaaataccag
accatcaggaaagctggaaaagtgcattatcccgtagcgtgggtgaacaccatggttttc
gacttcaaaggacagctgagatctggagacgtaatactgcatagctggtcttcatttcct
gatgaacttgaagaaatgttgaatccaatgggaaccgttcaaacaaatccatatactgaa
aacgcaacagctttgcatatcaagtttccagagaataaaaaacagccttattactatcct
ccctttgataagattattgagaaggcagctgagatcgcaagcagtgatagtgctaatgta
tcaagtcggggtggaaaaaagtttcttgctgtcctgaaggagatcttggacagggacccc
ctgtctcagctgtgtgagaatgagatggatcttatctggactctgcgacaggactgcaga
gagaacttcccacagtcactgcccaagctgctgctgtcgatcaagtggaataagcttgag
gacgttgctcagctccaagcactgcttcagatttggcccaaactgcccccgcgggaggcc
ctggagcttctggacttcaactacccagaccagtacgtgcgggaatatgccgtggagtgc
ctgcaacagatgagtgatgaagaactctcgcagtaccttttacaactggtgcaagtgtta
aaatacgagcctttccttgattgtgccctgtctagattcctgctagaaagggcacttgct
aatcggaggataggacagtttctgttttggcatcttaggtccgaagtgcacattcccgcc
gtctcagtgcagttcggcgtcatcctggaagcttattgccggggaagcgtaggtcacatg
aaagtgctttccaaacaggttgaagcactcaataaattaaaaactttaaatagtttaatc
aaactgaatgcaatgaagctaaacagagccaaagggaaggaagccatgcacacctgttta
aaacagaatgcttaccgggaagctctctctgacctgcagtcacccctgaacccgtgtgtt
atcctctcagagctctatgttgaaaaatgcaaatacatggattctaaaatgaagcctttg
tggctggtgtataacaacaaagtatttggtgaggactcagttggagttatttttaaaaat
ggtgatgatttacgacaggatatgctgaccctccagatgctgcgactgatggatttactc
tggaaggaagcgggactggatcttcggatgctgccctacggctgcctcgccacaggagac
cgctccggcctcatcgaagtcgtgagcacctccgagaccatcgctgacattcagctgaac
agcagcaatgtggccgccgccgccgccttcaacaaggacgcccttctcaactggctgaaa
gagtacaactctggggatgacctggaccgagccattgaagaatttaccctgtcttgtgct
ggctactgtgtagcttcttacgtccttgggattggtgacagacatagtgacaatattatg
gtcaaaaaaactggccagctcttccacattgattttggacatattctcggaaatttcaaa
tctaaatttggtattaaaagggagcgagtgccttttatccttacctatgacttcattcat
gtcattcaacaaggaaaaacggggaacacggaaaagtttggccggttccgccagtgctgt
gaggacgcgtacctggtcttgcgccgccacgggaacctcttcattaccctgttcgccctg
atgctgaccgccggcctgcccgagctcacgtccgtcaaggatattcagtatcttaaggat
tctcttgccttagggaagagtgaagaagaagcactcaaacaatttaagcaaaagttcgac
gaggcgctcagggaaagctggacgactaaggtgaactggatggcccacacggtgcggaaa
gactacagatcctaa

DBGET integrated database retrieval system