KEGG   Ursus maritimus (polar bear): 103656766
Entry
103656766         CDS       T03271                                 
Symbol
GSTO1
Name
(RefSeq) glutathione S-transferase omega-1
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
umr  Ursus maritimus (polar bear)
Pathway
umr00480  Glutathione metabolism
umr00980  Metabolism of xenobiotics by cytochrome P450
umr00982  Drug metabolism - cytochrome P450
umr00983  Drug metabolism - other enzymes
umr01100  Metabolic pathways
umr01524  Platinum drug resistance
umr05200  Pathways in cancer
umr05204  Chemical carcinogenesis - DNA adducts
umr05207  Chemical carcinogenesis - receptor activation
umr05208  Chemical carcinogenesis - reactive oxygen species
umr05225  Hepatocellular carcinoma
umr05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:umr00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    103656766 (GSTO1)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    103656766 (GSTO1)
   00982 Drug metabolism - cytochrome P450
    103656766 (GSTO1)
   00983 Drug metabolism - other enzymes
    103656766 (GSTO1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    103656766 (GSTO1)
   05204 Chemical carcinogenesis - DNA adducts
    103656766 (GSTO1)
   05207 Chemical carcinogenesis - receptor activation
    103656766 (GSTO1)
   05208 Chemical carcinogenesis - reactive oxygen species
    103656766 (GSTO1)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    103656766 (GSTO1)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    103656766 (GSTO1)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    103656766 (GSTO1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:umr02000]
    103656766 (GSTO1)
Enzymes [BR:umr01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     103656766 (GSTO1)
Transporters [BR:umr02000]
 Other transporters
  Pores ion channels [TC:1]
   103656766 (GSTO1)
SSDB
Motif
Pfam: GST_N_2 GST_N_3 GST_N GST_C_3 GST_C GST_C_2 Glutaredoxin
Other DBs
NCBI-GeneID: 103656766
NCBI-ProteinID: XP_040479880
UniProt: A0A8M1FCD4
Position
Unknown
AA seq 241 aa
MSGGSARSLGKGSAPPGPVPEGLIRVYSMRFCPFAQRTRLVLKAKGIRHEIININLKNKP
EWFFKKNPFGLVPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKAYQKMVFELF
SKIPSLVASFLRRQNEEDCSGLKEELRKEFSKLEEVLTNKKTTFFGGNSVSMIDYLIWPW
FERLEVLELNDCADHTLELKLWMAAMREDPAVSALLTEPKVFRGFLSLYLQNSPDACDYG
L
NT seq 726 nt   +upstreamnt  +downstreamnt
atgtccggagggtcggccaggagcctagggaagggaagcgcgcccccgggaccggtcccc
gagggcctgatccgcgtctacagcatgaggttctgcccgttcgcgcagaggacacgcctg
gtcctgaaggccaagggaatcaggcatgaaatcatcaacatcaacctgaaaaataagcct
gagtggttctttaagaagaatccctttggcctggtgccagttctggaaaacagtcagggt
caactgatctacgaatctgccatcacttgtgagtacctggatgaagcctatcccgggaag
aagctgttgccagacgacccctatgagaaagcttaccaaaagatggtgttcgagttattt
tcgaagattccatctttggtagcaagctttctgagaagacaaaatgaggaagactgctct
ggcctaaaagaagaattgcggaaagaattcagcaagcttgaggaggttcttaccaataag
aagacaaccttctttggtggcaattctgtttctatgattgattacctcatctggccctgg
tttgaacggctggaagttctggagttaaatgattgtgcagaccacactcttgaacttaag
ctctggatggcagccatgagggaagatcctgcagtgtcagccctcctcactgagcccaag
gtctttcgaggtttcctcagtctctatttgcagaacagccccgacgcctgtgactatggg
ctctga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (12)   
   KEGG PATHWAY (12)   
Chemical substance (45)   
   KEGG COMPOUND (45)   
Chemical reaction (23)   
   KEGG ENZYME (1)   
   KEGG REACTION (22)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (5)   
   RefSeq(nuc) (1)   
   GenBank (2)   
   EMBL (2)   
Protein domain (7)   
   Pfam (7)   
All databases (102)   

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