KEGG   Ursus maritimus (polar bear): 103675835
Entry
103675835         CDS       T03271                                 
Symbol
FOXO3
Name
(RefSeq) forkhead box protein O3
  KO
K09408  forkhead box protein O3
Organism
umr  Ursus maritimus (polar bear)
Pathway
umr01521  EGFR tyrosine kinase inhibitor resistance
umr04062  Chemokine signaling pathway
umr04068  FoxO signaling pathway
umr04137  Mitophagy - animal
umr04151  PI3K-Akt signaling pathway
umr04152  AMPK signaling pathway
umr04211  Longevity regulating pathway
umr04213  Longevity regulating pathway - multiple species
umr04218  Cellular senescence
umr04722  Neurotrophin signaling pathway
umr04917  Prolactin signaling pathway
umr04936  Alcoholic liver disease
umr05208  Chemical carcinogenesis - reactive oxygen species
umr05213  Endometrial cancer
umr05223  Non-small cell lung cancer
Brite
KEGG Orthology (KO) [BR:umr00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04068 FoxO signaling pathway
    103675835 (FOXO3)
   04151 PI3K-Akt signaling pathway
    103675835 (FOXO3)
   04152 AMPK signaling pathway
    103675835 (FOXO3)
 09140 Cellular Processes
  09141 Transport and catabolism
   04137 Mitophagy - animal
    103675835 (FOXO3)
  09143 Cell growth and death
   04218 Cellular senescence
    103675835 (FOXO3)
 09150 Organismal Systems
  09151 Immune system
   04062 Chemokine signaling pathway
    103675835 (FOXO3)
  09152 Endocrine system
   04917 Prolactin signaling pathway
    103675835 (FOXO3)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    103675835 (FOXO3)
  09149 Aging
   04211 Longevity regulating pathway
    103675835 (FOXO3)
   04213 Longevity regulating pathway - multiple species
    103675835 (FOXO3)
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    103675835 (FOXO3)
  09162 Cancer: specific types
   05213 Endometrial cancer
    103675835 (FOXO3)
   05223 Non-small cell lung cancer
    103675835 (FOXO3)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    103675835 (FOXO3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    103675835 (FOXO3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:umr03000]
    103675835 (FOXO3)
Transcription factors [BR:umr03000]
 Eukaryotic type
  Helix-turn-helix
   Fork head/winged helix other regulators
    103675835 (FOXO3)
SSDB
Motif
Pfam: FOXO_KIX_bdg Forkhead FOXO-TAD
Other DBs
NCBI-GeneID: 103675835
NCBI-ProteinID: XP_040483538
UniProt: A0A8M1FJH8
Position
Unknown
AA seq 672 aa
MAEAPASPAPLSPLEVELDPEFEPQSRPRSCTWPLQRPELQGSPAKPSGETAADSMIPEE
EDDEDDEDGSGRAGSAMAIGGGGSGTLGSGLLLEDSARLLAPGGQDSGSGPAPAAGALSG
GTQTPLQPQQPLPPPQPGAAGGSGQPRKCSSRRNAWGNLSYADLITRAIESSPDKRLTLS
QIYEWMVRCVPYFKDKGDSNSSAGWKNSIRHNLSLHSRFMRVQNEGTGKSSWWIINPDGG
KSGKAPRRRAVSMDNSNKYTKSRGRAAKKKAALQTAPESADDSPSQLSKWPGSPTSRSSD
ELDAWTDFRSRTNSNASTVSGRLSPILASTELDDVQDDDAPLSPMLYSSSASLSPSVSKP
CTVELPRLTDMAGTMNLNDGLSDNLMDDLLDNITLPSSQPSPTGGLMQRSSSFPYTTKGS
GLGSPTGSFNSTVFGPSSLNSLRQSPMQTIQENKPATFSSMSHYGNQTLQDLLTSDSLSH
SDVMMTQSDPLMSQASTAVSAQNSRRNVMLRNDPMMSFAAQPNQGSLVNQNLLHHQHQTQ
GALGGSRALSNSVSNMGLSDSSSLGSVKHQQQSPVSQSMQTLSDSLSGSSLYSTSANLPV
MGHEKFPSDLDLDMFNGSLECDMESIIRSELMDADGLDFNFDSLISTQNVVGLNVGNFTG
AKQASSQSWVPG
NT seq 2019 nt   +upstreamnt  +downstreamnt
atggcagaggcaccggcctctccggccccgctctctccgctcgaagtggagctggacccg
gagttcgagccccagagccggccgcgctcctgtacgtggcccctgcagaggccagagctc
caggggagcccggccaagccctcgggggagacggccgccgattctatgatccccgaagag
gaggacgatgaagacgacgaggacggcagcggtagggctggctcggccatggcgatcggc
ggcggcgggagcggcaccctgggctccgggctgctccttgaagactcggcccggctgctg
gctcccggaggacaggactccgggtccgggccagcccccgcggcgggcgcgctgagcggg
gggacgcagacgccgctgcagcctcagcagccactgccgccgccgcagccgggggcggct
gggggctccgggcagccgaggaaatgctcgtcgcggcggaacgcctgggggaacctgtcc
tacgccgacctgatcactcgcgccatcgagagctcgccggacaaacggctcactctgtcc
cagatctacgagtggatggtgcgctgcgtgccctacttcaaggataagggcgacagcaac
agctctgcggggtggaagaactctatccggcacaacctgtcactgcacagccggttcatg
cgggtccagaatgaggggactggcaagagctcttggtggatcatcaaccctgatggggga
aagagcgggaaggcaccccggcggcgggctgtctccatggacaacagcaacaagtatacc
aagagccgtggccgtgcagccaaaaagaaggcagccctgcagacagcccccgagtcagca
gatgatagtccctcccagctctccaagtggcctggcagccccacatcacgcagcagcgat
gagctggatgcatggacagacttccgctcgcgcaccaattccaatgccagcaccgtcagc
ggccgcctgtcacccatcttggcaagcacagagttggatgacgtccaggatgacgatgcg
ccactctcccccatgctctacagcagctcagctagcctctcaccctctgtaagtaagcca
tgcaccgtggagctaccacggctgaccgacatggcaggcaccatgaatctgaatgatggg
ctgtctgacaacctcatggatgacctgctggataacatcacgctcccatcgtcccagcca
tcgcccactggagggctcatgcagcggagctctagcttcccatataccaccaagggctcc
ggcctgggttctccaactggctcctttaacagcacggtgtttggaccctcgtctctgaat
tccctgcgccagtctcccatgcagaccatccaagagaataagccagctaccttctcttcc
atgtcccactatggcaaccaaacactccaggacctgctcacttcagactcactcagccac
agtgatgtcatgatgacccagtcagaccccttgatgtctcaggccagcaccgctgtgtcc
gcccagaactcccgccggaacgtgatgcttcgaaatgacccaatgatgtcctttgctgcc
cagcctaaccaggggagtttggtcaatcagaacttgctccaccaccagcaccaaacccag
ggcgctctcggtggcagccgtgccttgtcgaattctgtcagcaacatgggcttgagcgac
tccagcagccttgggtcagttaaacaccagcaacagtctcctgtcagccagtctatgcaa
accctctcggactctctctcaggctcctccttgtactcaactagtgcaaaccttcccgtc
atgggccatgagaagttccccagcgacttggacctggacatgttcaatgggagcttggaa
tgtgacatggagtccattatccgtagcgaactcatggatgctgatgggttggattttaat
tttgattccctcatctccacacagaatgttgttggtttgaacgtggggaacttcactggt
gctaagcaggcctcatctcagagctgggtgccaggctga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (15)   
   KEGG PATHWAY (15)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (5)   
   RefSeq(nuc) (1)   
   GenBank (2)   
   EMBL (2)   
Protein domain (3)   
   Pfam (3)   
All databases (32)   

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