ID   A0A010QFB0_9PEZI        Unreviewed;       507 AA.
AC   A0A010QFB0;
DT   11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT   11-JUN-2014, sequence version 1.
DT   24-JAN-2024, entry version 39.
DE   RecName: Full=cysteine desulfurase {ECO:0000256|ARBA:ARBA00012239};
DE            EC=2.8.1.7 {ECO:0000256|ARBA:ARBA00012239};
GN   ORFNames=CFIO01_05527 {ECO:0000313|EMBL:EXF78587.1};
OS   Colletotrichum fioriniae PJ7.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Glomerellales; Glomerellaceae; Colletotrichum;
OC   Colletotrichum acutatum species complex.
OX   NCBI_TaxID=1445577 {ECO:0000313|EMBL:EXF78587.1, ECO:0000313|Proteomes:UP000020467};
RN   [1] {ECO:0000313|EMBL:EXF78587.1, ECO:0000313|Proteomes:UP000020467}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PJ7 {ECO:0000313|EMBL:EXF78587.1,
RC   ECO:0000313|Proteomes:UP000020467};
RA   Baroncelli R., Thon M.R.;
RT   "The genome sequence of Colletotrichum fioriniae PJ7.";
RL   Submitted (FEB-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933,
CC         ECO:0000256|RuleBase:RU004504};
CC   -!- SIMILARITY: Belongs to the class-V pyridoxal-phosphate-dependent
CC       aminotransferase family. NifS/IscS subfamily.
CC       {ECO:0000256|ARBA:ARBA00006490}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EXF78587.1}.
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DR   EMBL; JARH01000625; EXF78587.1; -; Genomic_DNA.
DR   RefSeq; XP_007597752.1; XM_007597690.1.
DR   AlphaFoldDB; A0A010QFB0; -.
DR   STRING; 1445577.A0A010QFB0; -.
DR   KEGG; cfj:CFIO01_05527; -.
DR   eggNOG; KOG1549; Eukaryota.
DR   HOGENOM; CLU_003433_0_2_1; -.
DR   OrthoDB; 212394at2759; -.
DR   Proteomes; UP000020467; Unassembled WGS sequence.
DR   GO; GO:0031071; F:cysteine desulfurase activity; IEA:UniProtKB-EC.
DR   GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0044571; P:[2Fe-2S] cluster assembly; IEA:InterPro.
DR   Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR   HAMAP; MF_00331; Cys_desulf_IscS; 1.
DR   InterPro; IPR000192; Aminotrans_V_dom.
DR   InterPro; IPR020578; Aminotrans_V_PyrdxlP_BS.
DR   InterPro; IPR010240; Cys_deSase_IscS.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR   NCBIfam; TIGR02006; IscS; 1.
DR   PANTHER; PTHR11601:SF34; CYSTEINE DESULFURASE, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR11601; CYSTEINE DESULFURYLASE FAMILY MEMBER; 1.
DR   Pfam; PF00266; Aminotran_5; 1.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR   PROSITE; PS00595; AA_TRANSFER_CLASS_5; 1.
PE   3: Inferred from homology;
KW   Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000020467}.
FT   DOMAIN          108..472
FT                   /note="Aminotransferase class V"
FT                   /evidence="ECO:0000259|Pfam:PF00266"
SQ   SEQUENCE   507 AA;  55984 MW;  2C3DD01D4F283D80 CRC64;
     MASITSSALR QAGRLCRYTQ VPGVPSRGIS SLSRVAVSPT HRLSQQRRYV SETKRDNAQV
     NIETAIKLDK KDFIDVVPQS PDASNVMVSP MAEVLKQVTT MEEGQRPIYL DMQATTPVDP
     RVLDAMLPFM TGIYGNPHSR THAYGWESEE AVEEARGHIA KLIGADPKEI IFTSGATESN
     NMSIKGVARF FGRSGKKKHI VTSQTEHKCV LDSCRHLQDE GFEVTYLPVK NSGLIDMEEL
     AAAIRPDTAI VSIMSVNNEI GVIQPLEAIG KLCREKKTFF HTDAAQAVGK IPMDVNKMNI
     DLMSISSHKI YGPKGIGACY VRRRPRVRLD PIISGGGQER GLRSGTLAPP LIAGFGEACR
     IAYEEMEYDS KRIKFLSDRL LHGLLSLEHT TQNGDPEHFY PGCVNVSFAY VEGESLLMAL
     KDIALSSGSA CTSASLEPSY VLRALGNSDE SAHSSIRFGI GRFTTEQEID YVLKAVKERV
     DFLRELSPLW ELVQEGVDLN TIQWSQH
//