ID   A0A011M3N1_9PROT        Unreviewed;       395 AA.
AC   A0A011M3N1;
DT   11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT   11-JUN-2014, sequence version 1.
DT   24-JAN-2024, entry version 23.
DE   SubName: Full=UDP-N-acetyl-alpha-D-glucosamine C6 dehydratase {ECO:0000313|EMBL:EXI64208.1};
DE            EC=4.2.1.135 {ECO:0000313|EMBL:EXI64208.1};
GN   Name=pglF_2 {ECO:0000313|EMBL:EXI64208.1};
GN   ORFNames=AW08_03766 {ECO:0000313|EMBL:EXI64208.1};
OS   Candidatus Accumulibacter adjunctus.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Candidatus Accumulibacter.
OX   NCBI_TaxID=1454001 {ECO:0000313|EMBL:EXI64208.1, ECO:0000313|Proteomes:UP000020218};
RN   [1] {ECO:0000313|EMBL:EXI64208.1, ECO:0000313|Proteomes:UP000020218}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SK-12 {ECO:0000313|Proteomes:UP000020218};
RA   Skennerton C.T., Barr J.J., Slater F.R., Bond P.L., Tyson G.W.;
RT   "Expanding our view of genomic diversity in Candidatus Accumulibacter
RT   clades.";
RL   Submitted (FEB-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the polysaccharide synthase family.
CC       {ECO:0000256|ARBA:ARBA00007430}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EXI64208.1}.
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DR   EMBL; JFAX01000039; EXI64208.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A011M3N1; -.
DR   STRING; 1454001.AW08_03766; -.
DR   PATRIC; fig|1454001.3.peg.3798; -.
DR   Proteomes; UP000020218; Unassembled WGS sequence.
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   CDD; cd05237; UDP_invert_4-6DH_SDR_e; 1.
DR   Gene3D; 3.90.25.40; -; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR003869; Polysac_CapD-like.
DR   PANTHER; PTHR43318:SF1; POLYSACCHARIDE BIOSYNTHESIS PROTEIN EPSC-RELATED; 1.
DR   PANTHER; PTHR43318; UDP-N-ACETYLGLUCOSAMINE 4,6-DEHYDRATASE; 1.
DR   Pfam; PF02719; Polysacc_synt_2; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   3: Inferred from homology;
KW   Lyase {ECO:0000313|EMBL:EXI64208.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000020218}.
FT   DOMAIN          35..269
FT                   /note="Polysaccharide biosynthesis protein CapD-like"
FT                   /evidence="ECO:0000259|Pfam:PF02719"
SQ   SEQUENCE   395 AA;  44689 MW;  6ED0874502F01917 CRC64;
     MNTLELIGRQ EELFDGDLAA RASEMSTRVA ASRFLVIGGA GSIGQAVTRE IFARQPKVLH
     VVDISENNMV ELVRDIRSTL GYIDGDFSTF AIDCGSREFE ALMAASDGYD YILNLSALKH
     VRSEKDPFTL MRMIEVNILN TIRTIEFGRQ MNARKYFCVS TDKAANPVNM MGASKRVMEM
     FLMRDSLETP VSTARFANVA FSDGSLLHGF NQRLAKRQPI SAPRDVRRYF VTPQESGQLC
     LMSCLLGDNR DIFFPKLSAK LHLITFSEIA VKYLRALGYE AFVCSSEEEA RSLAAELIPA
     RKWPCYFFDS DTTGEKDFEE FFTGTEVLDM ARFESIGVIR NNATFDADKL SRFVDAVISL
     RQRGRWEKRE LVELFLSMLP DFGHKETGKY LDGRM
//