ID   A0A011Q5M7_9PROT        Unreviewed;       745 AA.
AC   A0A011Q5M7;
DT   11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT   11-JUN-2014, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=Biodegradative arginine decarboxylase {ECO:0000313|EMBL:EXI84592.1};
DE            EC=4.1.1.19 {ECO:0000313|EMBL:EXI84592.1};
GN   Name=adiA_2 {ECO:0000313|EMBL:EXI84592.1};
GN   ORFNames=AW12_02427 {ECO:0000313|EMBL:EXI84592.1};
OS   Candidatus Accumulibacter sp. BA-94.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Candidatus Accumulibacter.
OX   NCBI_TaxID=1454005 {ECO:0000313|EMBL:EXI84592.1, ECO:0000313|Proteomes:UP000020878};
RN   [1] {ECO:0000313|EMBL:EXI84592.1, ECO:0000313|Proteomes:UP000020878}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BA-94 {ECO:0000313|Proteomes:UP000020878};
RA   Skennerton C.T., Barr J.J., Slater F.R., Bond P.L., Tyson G.W.;
RT   "Expanding our view of genomic diversity in Candidatus Accumulibacter
RT   clades.";
RL   Submitted (FEB-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the Orn/Lys/Arg decarboxylase class-I family.
CC       {ECO:0000256|ARBA:ARBA00010671}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EXI84592.1}.
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DR   EMBL; JEMZ01000142; EXI84592.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A011Q5M7; -.
DR   STRING; 1454005.AW12_02427; -.
DR   PATRIC; fig|1454005.3.peg.2375; -.
DR   Proteomes; UP000020878; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR   GO; GO:0008792; F:arginine decarboxylase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006520; P:amino acid metabolic process; IEA:InterPro.
DR   Gene3D; 3.40.50.2300; -; 1.
DR   Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR   Gene3D; 3.90.100.10; Orn/Lys/Arg decarboxylase, C-terminal domain; 1.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR   InterPro; IPR005308; OKR_de-COase_N.
DR   InterPro; IPR011193; Orn/lys/arg_de-COase.
DR   InterPro; IPR000310; Orn/Lys/Arg_deCO2ase_major_dom.
DR   InterPro; IPR008286; Prn/Lys/Arg_de-COase_C.
DR   InterPro; IPR036633; Prn/Lys/Arg_de-COase_C_sf.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR   PANTHER; PTHR45229:SF3; BIODEGRADATIVE ARGININE DECARBOXYLASE; 1.
DR   PANTHER; PTHR45229; CONSTITUTIVE ORNITHINE DECARBOXYLASE; 1.
DR   Pfam; PF01276; OKR_DC_1; 1.
DR   Pfam; PF03711; OKR_DC_1_C; 1.
DR   Pfam; PF03709; OKR_DC_1_N; 1.
DR   PIRSF; PIRSF009393; Orn_decarb; 1.
DR   SUPFAM; SSF55904; Ornithine decarboxylase C-terminal domain; 1.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR   PROSITE; PS00703; OKR_DC_1; 1.
PE   3: Inferred from homology;
KW   Lyase {ECO:0000313|EMBL:EXI84592.1};
KW   Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW   ECO:0000256|PIRSR:PIRSR009393-1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000020878}.
FT   DOMAIN          388..402
FT                   /note="Orn/Lys/Arg decarboxylases family 1 pyridoxal-P
FT                   attachment site"
FT                   /evidence="ECO:0000259|PROSITE:PS00703"
FT   MOD_RES         393
FT                   /note="N6-(pyridoxal phosphate)lysine"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR009393-1"
SQ   SEQUENCE   745 AA;  83877 MW;  A397EDE34A9A917E CRC64;
     MHFAFPVIII DKDYRSENTG GLGIRALAKA IEKKGFEVLG VTSYGDLTSF AQQQSRASAF
     ILSIDDEDFR DGKADDTVAS LRAFVKEIRC RNEDIPIFLY GETRTSGHIP NDVLRELHGF
     IHMFEDTAEF IGRYVIREAK TYLDSLAPPF FRALTHYAED GSYSWHCPGH SGGVAFLKSP
     VGRMFHQFFG ENMLRADVCN AVEELGQLLD HTGPVAASER NAARIFNADH LFFVTNGTST
     SNKIVWHSTV APGDVVVVDR NCHKSVLHSI IMTGAIPVFL MPTRNHYGII GPIPKEQFRW
     ENIRKKIEAH PFARAVTAKP RVLTITQSTY DGILYNVEEI KEMLDGAIDT LHFDEAWLPH
     AAFHEFYGDY HAIGADRPRC KDAMIFSTQS THKLLAGLSQ ASQILVQNSE GRKLDRDIFN
     EAYLMHTSTS PQYAIIASCD VAAAMMEAPG GTALVEESIA EALNFRRTMR KVEQEWGADW
     WFKVWGPDDL SEEGIEERAA WILKPGERWH GFGMLAEGFN MLDPIKATVI TPGLDVDGDF
     ADWGIPAAIV TKYLAEHGII VEKCGLYSFF IMFTIGITKG RWNTMVTELQ QFKDSYDQNL
     PLWKVMPEFL TKNPRYERYG LKDLCKQIHG IYAANDVAHL TTEMYLSDME PAMKPTDAFA
     SMAHREIDRV PIDDLEGRIT STLLTPYPPG IPLLIPGERF NATIVRYLRF ARDFNERFPG
     FETDVHGLVK ALVNGKAVYS VDCVR
//