ID   A0A016SAJ6_9BILA        Unreviewed;      1546 AA.
AC   A0A016SAJ6;
DT   11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT   11-JUN-2014, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   RecName: Full=Carboxypeptidase {ECO:0000256|RuleBase:RU361156};
DE            EC=3.4.16.- {ECO:0000256|RuleBase:RU361156};
GN   Name=Acey_s0263.g601 {ECO:0000313|EMBL:EYB87431.1};
GN   ORFNames=Y032_0263g601 {ECO:0000313|EMBL:EYB87431.1};
OS   Ancylostoma ceylanicum.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC   Ancylostomatinae; Ancylostoma.
OX   NCBI_TaxID=53326 {ECO:0000313|EMBL:EYB87431.1, ECO:0000313|Proteomes:UP000024635};
RN   [1] {ECO:0000313|Proteomes:UP000024635}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=HY135 {ECO:0000313|Proteomes:UP000024635};
RX   PubMed=25730766; DOI=10.1038/ng.3237;
RA   Schwarz E.M., Hu Y., Antoshechkin I., Miller M.M., Sternberg P.W.,
RA   Aroian R.V.;
RT   "The genome and transcriptome of the zoonotic hookworm Ancylostoma
RT   ceylanicum identify infection-specific gene families.";
RL   Nat. Genet. 47:416-422(2015).
CC   -!- SIMILARITY: Belongs to the peptidase S10 family.
CC       {ECO:0000256|ARBA:ARBA00009431, ECO:0000256|RuleBase:RU361156}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EYB87431.1}.
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DR   EMBL; JARK01001599; EYB87431.1; -; Genomic_DNA.
DR   STRING; 53326.A0A016SAJ6; -.
DR   MEROPS; S10.A60; -.
DR   Proteomes; UP000024635; Unassembled WGS sequence.
DR   GO; GO:0004185; F:serine-type carboxypeptidase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 3.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR001563; Peptidase_S10.
DR   InterPro; IPR033124; Ser_caboxypep_his_AS.
DR   InterPro; IPR018202; Ser_caboxypep_ser_AS.
DR   PANTHER; PTHR11802:SF480; CARBOXYPEPTIDASE; 1.
DR   PANTHER; PTHR11802; SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE; 1.
DR   Pfam; PF00450; Peptidase_S10; 3.
DR   PRINTS; PR00724; CRBOXYPTASEC.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 3.
DR   PROSITE; PS00560; CARBOXYPEPT_SER_HIS; 3.
DR   PROSITE; PS00131; CARBOXYPEPT_SER_SER; 2.
PE   3: Inferred from homology;
KW   Carboxypeptidase {ECO:0000256|RuleBase:RU361156};
KW   Hydrolase {ECO:0000256|RuleBase:RU361156};
KW   Protease {ECO:0000256|RuleBase:RU361156};
KW   Reference proteome {ECO:0000313|Proteomes:UP000024635}.
FT   REGION          1478..1504
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1546 AA;  172044 MW;  62CE06BA032267CB CRC64;
     MILVENERFL ETLGTTWEED LNRVVILGCP RNDGRSRGES YGGVYVPVLT SLLIDNIQAG
     NLPGLNLAGM AVGNGELSAI QQLNSIIHMA YFHGIYGKQE WDLLQKCCPQ TGSATWFEYC
     DFSQYITFDS AGNAHPKTSS GECGALIAQM GQTDIWNSLN DVYNIYQDCY QQSSKVFGTR
     IKSHQRQGIV DYFVDQGQKV SISSTDNQGG FQCYASDAAA QYLNQDDVRN ALHIVSTAGN
     WSSCNDDMNN NYIQQHNDTG KVFDHILRSG YPLRMLIYNG DVDQACNFLG DQWFVEAVAA
     RWNMSVSKDF NSWWYRTQIA GYVKQFTYGP ASIDLLTVKG AGHLVPSDRP GPALQMFENF
     LRGQDYSKEL PFNYQLHPLK EDYQIQETVT AERTGMPVPG SVSTRKLKLK SRKMRKNKST
     ALRERFASAP LDPPPIGTKQ DDLVTDLPGL TWKPNFNHYS GYLAASPGNY LHYWLTESQG
     SPKDDPLILW LNGGPGCSSL GGLFEELGPF HINSDGTTLF ENVFSWNKVG NVLFMEAPRD
     VGFSYRASNV SDSKYNDDYT ASDNVLALAS FFTKFPEYKN RTFFITGESY GGVYVPTLTS
     ALIKKIQSKG SDSMSYVNLA GVAIGNGEMS EIQQINSAVS LLYFRGEHGK SDYDALSKCC
     NTTSPQAYCD FTSYITLDVA GNAWPKVNDN SIAGQCGNLV VQQGFNDVWG TANDVYNTFQ
     DCYSTAPDGT RSRRKRSVDM PPLMNSKPFV DQAKTINYQS TDANGGFACF NGDATEAYLN
     LATVRKAIHI PENFTHWSDC NDNMNANYIQ QHNDTSSVFV DILNSGYPLR FLIYNGDVDM
     ACQFLGDEWF IEKLAADNGM TSNTRAPWNY TQGSFMPRLG GYVKSFQYKN SASFDLLTVK
     GGGHFVPTDR PGPALQMIYN FVNKLDYSTN LTLSLTRQPL LPQYTPVVPT VPRMKADKIG
     ELPGLTFKPN FHHHAGYLRA SPGNYLHYWF IESQNNTQAD PLVLWLTGGP GCSSLGALLT
     ENGPFHPNPD GSTLFENVYS WNKGANVLYL ESPRLVGFSY QDKSLNDTLW NDDKEILVSL
     QTASDIYLAL KDFFTEYPQF STNDFFVTGE SYGGVYVPTL TRLLIQKIQA NDIKLNLVGM
     SIGNGMISTI QDIRSLPDFM YFHGIYGKAD WDKLHQCCPA SNASNSSAST SYCNYDYFVT
     VDQSGNILPK NFTDPRDQDC ANMVVNLAFT RVWNTENYIY NLYQDCYTQT TAMFGSAAEA
     KSRVHYDGPP SFTHSFAAQM SGLVPSPSTL DPISTDNFGG FQCYMVDAAS RYLSQSHVRQ
     ALHVPDFVQS WDFCSDVVGN NYVLQYNDTT SVFQDILNSG YNLRVLVYNG DADTACSMFE
     AEWMIESFAR INKMVVPSQR GAWMYGQQIA GYTKRFQTAN MTIDLLTVKG AGHFVPTDRP
     GPALQMISNF FAGHSNYNNP VPFDLTRRPL LAQYTEQGNG PINTANPSAP TTTTTTTTTT
     TTSTTTANNN AVATTTMVQP KTQSSHGSLI NLPLTLLFAF VFLLRF
//