ID A0A016SGX9_9BILA Unreviewed; 407 AA.
AC A0A016SGX9;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Peptidase S1 domain-containing protein {ECO:0000259|PROSITE:PS50240};
GN Name=Acey_s0230.g2977 {ECO:0000313|EMBL:EYB89591.1};
GN ORFNames=Y032_0230g2977 {ECO:0000313|EMBL:EYB89591.1};
OS Ancylostoma ceylanicum.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC Ancylostomatinae; Ancylostoma.
OX NCBI_TaxID=53326 {ECO:0000313|EMBL:EYB89591.1, ECO:0000313|Proteomes:UP000024635};
RN [1] {ECO:0000313|Proteomes:UP000024635}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=HY135 {ECO:0000313|Proteomes:UP000024635};
RX PubMed=25730766; DOI=10.1038/ng.3237;
RA Schwarz E.M., Hu Y., Antoshechkin I., Miller M.M., Sternberg P.W.,
RA Aroian R.V.;
RT "The genome and transcriptome of the zoonotic hookworm Ancylostoma
RT ceylanicum identify infection-specific gene families.";
RL Nat. Genet. 47:416-422(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EYB89591.1}.
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DR EMBL; JARK01001566; EYB89591.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A016SGX9; -.
DR STRING; 53326.A0A016SGX9; -.
DR Proteomes; UP000024635; Unassembled WGS sequence.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 2.40.10.10; Trypsin-like serine proteases; 1.
DR InterPro; IPR009003; Peptidase_S1_PA.
DR InterPro; IPR043504; Peptidase_S1_PA_chymotrypsin.
DR InterPro; IPR001314; Peptidase_S1A.
DR InterPro; IPR001254; Trypsin_dom.
DR InterPro; IPR018114; TRYPSIN_HIS.
DR InterPro; IPR033116; TRYPSIN_SER.
DR PANTHER; PTHR24260; -; 1.
DR PANTHER; PTHR24260:SF136; PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00089; Trypsin; 1.
DR PRINTS; PR00722; CHYMOTRYPSIN.
DR SMART; SM00020; Tryp_SPc; 1.
DR SUPFAM; SSF50494; Trypsin-like serine proteases; 1.
DR PROSITE; PS50240; TRYPSIN_DOM; 1.
DR PROSITE; PS00134; TRYPSIN_HIS; 1.
DR PROSITE; PS00135; TRYPSIN_SER; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Hydrolase {ECO:0000256|RuleBase:RU363034};
KW Protease {ECO:0000256|RuleBase:RU363034};
KW Reference proteome {ECO:0000313|Proteomes:UP000024635};
KW Serine protease {ECO:0000256|RuleBase:RU363034};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..407
FT /note="Peptidase S1 domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001486375"
FT DOMAIN 50..299
FT /note="Peptidase S1"
FT /evidence="ECO:0000259|PROSITE:PS50240"
SQ SEQUENCE 407 AA; 46135 MW; BC36D7B9D2462485 CRC64;
MLRFFLFFLL FALLFVNSRK LTTEENERNS KKCGVHFLGN EEQNRRSKRS YGGRKFKENE
YPWTVLLKGQ GECSGVLISQ RHVLTAAHCV LLYDDDHRAE QCNSDKNYNV VAVKISPRSV
FIHFRATETD CDDAEYCPPH DVAKITVHNL EICTLHNDIA LIELKENISE TVATPICMPS
EDLQLESVLY AAGSGMDHDA PITLADSSRS SRGQQVVAQR KHSFNKTTKK IVTVTFGKTI
LPGDSGGPLF QVDESDRHIL VGINSAGNTA RPKANVGQNF EAFHADVRSY LDWICKHSGV
CPIEDRRADA LPYIRLKKKN VNFKKNTISS LYSIETRRHP ILFERGSSAK YKRRRTLPME
VLEAQFGDTG KGGVRRYHGV KWLDQCEWIL SAELPQLLVR FESCDVI
//
