ID A0A016SH22_9BILA Unreviewed; 859 AA.
AC A0A016SH22;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=JmjC domain-containing protein {ECO:0000259|PROSITE:PS51184};
GN Name=Acey_s0230.g2966 {ECO:0000313|EMBL:EYB89574.1};
GN ORFNames=Y032_0230g2966 {ECO:0000313|EMBL:EYB89574.1};
OS Ancylostoma ceylanicum.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC Ancylostomatinae; Ancylostoma.
OX NCBI_TaxID=53326 {ECO:0000313|EMBL:EYB89574.1, ECO:0000313|Proteomes:UP000024635};
RN [1] {ECO:0000313|Proteomes:UP000024635}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=HY135 {ECO:0000313|Proteomes:UP000024635};
RX PubMed=25730766; DOI=10.1038/ng.3237;
RA Schwarz E.M., Hu Y., Antoshechkin I., Miller M.M., Sternberg P.W.,
RA Aroian R.V.;
RT "The genome and transcriptome of the zoonotic hookworm Ancylostoma
RT ceylanicum identify infection-specific gene families.";
RL Nat. Genet. 47:416-422(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EYB89574.1}.
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DR EMBL; JARK01001566; EYB89574.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A016SH22; -.
DR STRING; 53326.A0A016SH22; -.
DR Proteomes; UP000024635; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0051213; F:dioxygenase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR Gene3D; 1.20.58.1360; -; 1.
DR Gene3D; 2.60.120.650; Cupin; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR041070; JHD.
DR InterPro; IPR003347; JmjC_dom.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR23123:SF37; JMJC DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR PANTHER; PTHR23123; PHD/F-BOX CONTAINING PROTEIN; 1.
DR Pfam; PF17811; JHD; 1.
DR Pfam; PF02373; JmjC; 1.
DR Pfam; PF00628; PHD; 1.
DR SMART; SM00558; JmjC; 1.
DR SMART; SM00249; PHD; 1.
DR SUPFAM; SSF51197; Clavaminate synthase-like; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR PROSITE; PS51184; JMJC; 1.
DR PROSITE; PS01359; ZF_PHD_1; 1.
PE 4: Predicted;
KW Chromatin regulator {ECO:0000256|ARBA:ARBA00022853};
KW Dioxygenase {ECO:0000256|ARBA:ARBA00022964};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00022964};
KW Reference proteome {ECO:0000313|Proteomes:UP000024635};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 385..538
FT /note="JmjC"
FT /evidence="ECO:0000259|PROSITE:PS51184"
FT REGION 40..82
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 626..711
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 822..859
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 61..76
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 669..707
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 859 AA; 97664 MW; 23DA51EF2B61058E CRC64;
MENCGDDSTY ECGANRQYEF HEFIPSGSCS GLDSSNVVAV SRPSQPETVS LPTPPKVPRR
EGTEATVKKQ EPETEERYWS TSATADPKLE CKTDVIKTEE TSLGEHYVSG CSSGVLLPLS
IETKNEHSAG SFNECGVCGP EKAIWVPDTS DTGEPLIEPT SGHGLSIKID PIDTFWIQCD
ECEKWFHGSC VGVEEYEDVL IDKFHCGPCA AAKGPTKMKT ILLRHRFAFD DLSQANLPPE
VGTETWIKEF IKTEANIPPP NDQHVTICKT GFDFMDQFNR RADWKKVYLI EQARGLELRV
PDKNENFTLR SIVDILGRSY KVDTIDVYRQ MTQSMCIGTF YDKMIASQRM RLYNILSLEF
SQNESMRKMI SPPLLVPELS FVHKLWPDKN DLVNWDPELQ QVVEVLEEHR RNKPEVALFC
LCGMAGSYTD FHIDFGGSSV WYHIYEGQKI FYIVEPTDEY LDLFEEYQRS ETKTETFFGD
LLPPGALRRV VIEEGQTLMI PSGWIHAVYT PIDSLVFGGN FLHALNVPMQ LKIYEMEQRL
KKEVGTEDKY LFPHFELVNW YAARSFILEH LREANDEGNR AEQYMMDAAL ALLPRLKEWM
RRDKEDKANV THSSFNDVLV KLQREINKQQ RLRRSHSPLC RSPKKTTKKR RSEEHDISLE
PGPSTPRASE PVQLPSKESF SVETGSIKEN APVSEPISST GTESSADSHD ETPIDFRLKL
TKKGKNVCRN YASSVVEKPD PMLEDVNMTQ MFARRSSSGR KPRPAAWLAE AVGLDELEKT
AKQLEEQGEQ MPEREIVTYD TEMELACEEE ERNLLREERA KKKGKVVVGP GDPLRGVTGV
AKRKPSTVKQ RLAAKLKLK
//
