ID A0A016SRA2_9BILA Unreviewed; 665 AA.
AC A0A016SRA2;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=Intermediate filament tail domain protein {ECO:0008006|Google:ProtNLM};
GN Name=Acey_s0186.g1053 {ECO:0000313|EMBL:EYB93055.1};
GN ORFNames=Y032_0186g1053 {ECO:0000313|EMBL:EYB93055.1};
OS Ancylostoma ceylanicum.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC Ancylostomatinae; Ancylostoma.
OX NCBI_TaxID=53326 {ECO:0000313|EMBL:EYB93055.1, ECO:0000313|Proteomes:UP000024635};
RN [1] {ECO:0000313|Proteomes:UP000024635}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=HY135 {ECO:0000313|Proteomes:UP000024635};
RX PubMed=25730766; DOI=10.1038/ng.3237;
RA Schwarz E.M., Hu Y., Antoshechkin I., Miller M.M., Sternberg P.W.,
RA Aroian R.V.;
RT "The genome and transcriptome of the zoonotic hookworm Ancylostoma
RT ceylanicum identify infection-specific gene families.";
RL Nat. Genet. 47:416-422(2015).
CC -!- SIMILARITY: Belongs to the intermediate filament family.
CC {ECO:0000256|PIRNR:PIRNR005546, ECO:0000256|RuleBase:RU000685}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EYB93055.1}.
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DR EMBL; JARK01001522; EYB93055.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A016SRA2; -.
DR STRING; 53326.A0A016SRA2; -.
DR Proteomes; UP000024635; Unassembled WGS sequence.
DR GO; GO:0005882; C:intermediate filament; IEA:UniProtKB-UniRule.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 2.60.40.1260; Lamin Tail domain; 1.
DR Gene3D; 1.20.5.500; Single helix bin; 1.
DR Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 2.
DR InterPro; IPR018039; IF_conserved.
DR InterPro; IPR039008; IF_rod_dom.
DR InterPro; IPR016451; Intermed_filament_ifa/ifb.
DR InterPro; IPR001322; Lamin_tail_dom.
DR InterPro; IPR036415; Lamin_tail_dom_sf.
DR PANTHER; PTHR45721:SF12; INTERMEDIATE FILAMENT PROTEIN IFA-1; 1.
DR PANTHER; PTHR45721; LAMIN DM0-RELATED; 1.
DR Pfam; PF00038; Filament; 1.
DR Pfam; PF00932; LTD; 1.
DR PIRSF; PIRSF005546; Intermed_filamnt_Ifb-2; 2.
DR SMART; SM01391; Filament; 1.
DR SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 2.
DR SUPFAM; SSF74853; Lamin A/C globular tail domain; 1.
DR SUPFAM; SSF57997; Tropomyosin; 1.
DR PROSITE; PS00226; IF_ROD_1; 1.
DR PROSITE; PS51842; IF_ROD_2; 1.
DR PROSITE; PS51841; LTD; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|PIRNR:PIRNR005546};
KW Intermediate filament {ECO:0000256|ARBA:ARBA00022754,
KW ECO:0000256|PIRNR:PIRNR005546};
KW Reference proteome {ECO:0000313|Proteomes:UP000024635}.
FT DOMAIN 117..470
FT /note="IF rod"
FT /evidence="ECO:0000259|PROSITE:PS51842"
FT DOMAIN 503..662
FT /note="LTD"
FT /evidence="ECO:0000259|PROSITE:PS51841"
FT REGION 96..118
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 375..469
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 665 AA; 77442 MW; DB549689A638401A CRC64;
MDKDIHDYYT DFVDTHLHLQ PWYEISQDSR RESSLLAFST AKSRTQPTMM EITRETMSYS
TTQPGGRAPL GGRQAGNVVS QDRMLKIVTE MRSGAGSGLS PFGQNAASTI RDSREREKKE
MSDLNDRLAS YIEKVRFLEA QNRKLAADLD ALRSKWGKDT HNIRNMYEGE LSDAQKLIDE
TNRQRKEMEM QIKKMQDELA ELRRKYEDAV RGRETDRAKI DDLLVHLSNL EAEINLLKRR
IAQLEDEVKR IKQENQRLLS ELQRARTDLD QETLNRIDYQ NQVQTLLEEI DFLRRVHDNE
IKELQTLASR DTTPENREFF KNELSSAIRD IREEYDQITN VHRTDMESWY RLKVQEIQTQ
SARQSMEHGY AKEEVKRLRT QLSDLRGKLA DLESRNSLLE KQIQELNYQL EDDQRSYESA
LNDRDAQIRK MREECQALMV ELQMLLDTKQ TLDAEIAIYR KMLEGEENRA GLKQLVEQVV
KTHAITQETD TETMRVVKGE TASRQSFQRS AKGNVSIHEA SPDGKFIVLQ NTHRAKDESI
GEWKLKRRID GKREIVYSLP KDFVLRAGKS VKVSISPGTT SDFQDSLHKN TLYPCRSSLA
TKVFRRHLTS SYTMARIHSD PAVPSKPFSL TEREKYVQPR GNFYVTNNVH DFQERATHIQ
RQSNA
//
