ID A0A016SXS7_9BILA Unreviewed; 653 AA.
AC A0A016SXS7;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=ABC transporter, ATP-binding protein {ECO:0008006|Google:ProtNLM};
GN Name=Acey_s0163.g3465 {ECO:0000313|EMBL:EYB95124.1};
GN Synonyms=Acey-pmp-3 {ECO:0000313|EMBL:EYB95124.1};
GN ORFNames=Y032_0163g3465 {ECO:0000313|EMBL:EYB95124.1};
OS Ancylostoma ceylanicum.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC Ancylostomatinae; Ancylostoma.
OX NCBI_TaxID=53326 {ECO:0000313|EMBL:EYB95124.1, ECO:0000313|Proteomes:UP000024635};
RN [1] {ECO:0000313|Proteomes:UP000024635}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=HY135 {ECO:0000313|Proteomes:UP000024635};
RX PubMed=25730766; DOI=10.1038/ng.3237;
RA Schwarz E.M., Hu Y., Antoshechkin I., Miller M.M., Sternberg P.W.,
RA Aroian R.V.;
RT "The genome and transcriptome of the zoonotic hookworm Ancylostoma
RT ceylanicum identify infection-specific gene families.";
RL Nat. Genet. 47:416-422(2015).
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. ABCD family.
CC Peroxisomal fatty acyl CoA transporter (TC 3.A.1.203) subfamily.
CC {ECO:0000256|ARBA:ARBA00008575}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EYB95124.1}.
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DR EMBL; JARK01001499; EYB95124.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A016SXS7; -.
DR Proteomes; UP000024635; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd03223; ABCD_peroxisomal_ALDP; 1.
DR Gene3D; 1.20.1560.10; ABC transporter type 1, transmembrane domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011527; ABC1_TM_dom.
DR InterPro; IPR036640; ABC1_TM_sf.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR025662; Sigma_54_int_dom_ATP-bd_1.
DR PANTHER; PTHR11384; ATP-BINDING CASSETTE, SUB-FAMILY D MEMBER; 1.
DR PANTHER; PTHR11384:SF71; LYSOSOMAL COBALAMIN TRANSPORTER ABCD4; 1.
DR Pfam; PF06472; ABC_membrane_2; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF90123; ABC transporter transmembrane region; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50929; ABC_TM1F; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
DR PROSITE; PS00675; SIGMA54_INTERACT_1; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000024635};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 24..43
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 63..84
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 140..161
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 173..190
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 253..280
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 292..310
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 24..280
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
FT DOMAIN 416..649
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 653 AA; 74230 MW; E1975D118C52E9FC CRC64;
MLFIRRLGTL LKLLFPCHRR SKTAWLALVV LVTSFLDQVG TYFVGVLPSQ FYVALGNRDL
SAFHLLIAKA TVIVIAKSLS LASIKYFTSI LAIKCRELCS YTLHRLYFKR RAFYKLGTAS
EGLDNIDQRL TQDIEKTTQV LAVDLFAPVI TAPFIILYYS YLTWKSSGWM GPFTIYIYFA
FVTTVNRYLL SPIVGLVNET EKREGDFRQR HMEVRTNVEQ IAFYQSGLIE NIMSNQKLKM
LLKTKQKLVE WRFVLGIVTN IFDYFGGTLS YLIIAIPIFM THTYDSLSGT ELNGVVSMNA
FFYLYLIYSF TNLITLSEKL GDLAGVTHRV IELLEELRRL HSDCLETDRP PSTVPSSVVV
IGSEDEEKAA TNRAIEELHG KQLSLERDCD DEEEAQFLLG NNTDRDEECA DDGVAMTVDS
ATLAAPTDAH TIIIASLSVQ LIQGQNVLIT GDSGTGKTSL LRMFAGLWNN VSGKVDRHWR
QRPQNMLFVP QKSYFPSGGV TLRQQLVYPL KALPVEKDLV RLTQVLEWVK MEHLLERCQG
FDHPVDWDWN ETLSPGELQR LSMARVFYTK PRIAFLDEAT SAIGFEMEMQ LYRKLQEENI
TFVSVGHRFS LKQFHDMELR LLGRGEWAMY DIDSASIASR AASLLGNDTV ISM
//
