ID A0A016T483_9BILA Unreviewed; 533 AA.
AC A0A016T483;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=RRM domain-containing protein {ECO:0000259|PROSITE:PS50102};
GN Name=Acey_s0141.g2271 {ECO:0000313|EMBL:EYB97436.1};
GN Synonyms=Acey-psf-1 {ECO:0000313|EMBL:EYB97436.1};
GN ORFNames=Y032_0141g2271 {ECO:0000313|EMBL:EYB97436.1};
OS Ancylostoma ceylanicum.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC Ancylostomatinae; Ancylostoma.
OX NCBI_TaxID=53326 {ECO:0000313|EMBL:EYB97436.1, ECO:0000313|Proteomes:UP000024635};
RN [1] {ECO:0000313|Proteomes:UP000024635}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=HY135 {ECO:0000313|Proteomes:UP000024635};
RX PubMed=25730766; DOI=10.1038/ng.3237;
RA Schwarz E.M., Hu Y., Antoshechkin I., Miller M.M., Sternberg P.W.,
RA Aroian R.V.;
RT "The genome and transcriptome of the zoonotic hookworm Ancylostoma
RT ceylanicum identify infection-specific gene families.";
RL Nat. Genet. 47:416-422(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EYB97436.1}.
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DR EMBL; JARK01001477; EYB97436.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A016T483; -.
DR STRING; 53326.A0A016T483; -.
DR Proteomes; UP000024635; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd12931; eNOPS_SF; 1.
DR CDD; cd12332; RRM1_p54nrb_like; 1.
DR CDD; cd12333; RRM2_p54nrb_like; 1.
DR Gene3D; 3.30.70.330; -; 2.
DR Gene3D; 6.10.250.1170; -; 1.
DR InterPro; IPR012975; NOPS.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR PANTHER; PTHR23189:SF126; FI21126P1-RELATED; 1.
DR PANTHER; PTHR23189; RNA RECOGNITION MOTIF-CONTAINING; 1.
DR Pfam; PF08075; NOPS; 1.
DR Pfam; PF00076; RRM_1; 2.
DR SMART; SM00360; RRM; 2.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR PROSITE; PS50102; RRM; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000024635};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00176}.
FT DOMAIN 88..159
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 161..242
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 1..66
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 350..533
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..44
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 416..430
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 485..500
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 533 AA; 57582 MW; 48DFB53B7E31791A CRC64;
MSRHNNDRNN KRDERRHDDR RRSGRDDDDG SRSRREHHRS SNGGGSDMHR GMSMGGGPQR
GAGSFSGMAF TESELMGDLP KKKFTGRCRL FVGNLPNEVK EAELKELFSP HGDIAECYLS
GKGFAFLRMD TRAHAESAKE AIDGRVIHGR QVRVRFAVHG AALRVKELSP TVSNEMLYHA
FSHFGDVERA VHIVDEKGRP TGEGIVEFER KPSCNEAMQA IKEKVFLLTA SPKPLVVELL
EPRDEDDGLA ERMIPRTSQL IKERELGPRF PSQNTFEFVY GMKWKELYAM ERQRKAQLDE
ELKEARRRLE SDMELAYQDY QAQMLREDLQ RRQQELERLE AARRERLNMR AAAGAGGPPG
PGGPGGPGMG MGGPMQPFGQ PGPFAQSVPG GPMGGAPMGG PMGGPPMGGP PMGGHYQPQQ
YQQAPPNQMQ PQGGPGGPGG MGPGGPAGMG PGGPGGQGGP GGAQGGQRPA ANNMLEGVQR
LLQIFKNEPS GQQRPSSGGP NSFGGPGGPG SMSPFVGGPG GPGDYPPEKR MRR
//
