ID A0A016TF02_9BILA Unreviewed; 397 AA.
AC A0A016TF02;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Sidoreflexin {ECO:0000256|RuleBase:RU362000};
GN Name=Acey_s0109.g87 {ECO:0000313|EMBL:EYC01235.1};
GN Synonyms=Acey-sfxn-5 {ECO:0000313|EMBL:EYC01235.1};
GN ORFNames=Y032_0109g87 {ECO:0000313|EMBL:EYC01235.1};
OS Ancylostoma ceylanicum.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC Ancylostomatinae; Ancylostoma.
OX NCBI_TaxID=53326 {ECO:0000313|EMBL:EYC01235.1, ECO:0000313|Proteomes:UP000024635};
RN [1] {ECO:0000313|Proteomes:UP000024635}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=HY135 {ECO:0000313|Proteomes:UP000024635};
RX PubMed=25730766; DOI=10.1038/ng.3237;
RA Schwarz E.M., Hu Y., Antoshechkin I., Miller M.M., Sternberg P.W.,
RA Aroian R.V.;
RT "The genome and transcriptome of the zoonotic hookworm Ancylostoma
RT ceylanicum identify infection-specific gene families.";
RL Nat. Genet. 47:416-422(2015).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Mitochondrion
CC membrane {ECO:0000256|RuleBase:RU362000}; Multi-pass membrane protein
CC {ECO:0000256|RuleBase:RU362000}.
CC -!- SIMILARITY: Belongs to the sideroflexin family.
CC {ECO:0000256|ARBA:ARBA00005974, ECO:0000256|RuleBase:RU362000}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU362000}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EYC01235.1}.
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DR EMBL; JARK01001445; EYC01235.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A016TF02; -.
DR Proteomes; UP000024635; Unassembled WGS sequence.
DR GO; GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015075; F:monoatomic ion transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR004686; Mtc.
DR NCBIfam; TIGR00798; mtc; 1.
DR PANTHER; PTHR11153; SIDEROFLEXIN; 1.
DR PANTHER; PTHR11153:SF6; SIDEROFLEXIN-5; 1.
DR Pfam; PF03820; SFXNs; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362000};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128,
KW ECO:0000256|RuleBase:RU362000};
KW Reference proteome {ECO:0000313|Proteomes:UP000024635};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362000};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362000}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 169..187
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362000"
FT TRANSMEM 221..242
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362000"
FT TRANSMEM 345..367
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362000"
SQ SEQUENCE 397 AA; 44409 MW; 6EC7DF3095814124 CRC64;
MVRLIGKTER NLHAHYPSRM DARIWIKWSA LINPVTRDAP RIRLHPIIVE ALNAHVPCTV
TCGGHPMNQM SSDTVFGFVK YPPFRLNQPR FPQETFLGRY LHYLDVVDPS TLFVSDKRLR
ECVQLLDDYK LGKATAPDKE LWRAQKIKQA ILHPDTGEKV LAPFRMSGFV PFGWITVTGM
LLPNPSWPTL LFWQWMNQSH NACVNYANRN ATQPQPLSTY VGAYAAAVSA ACSISAGLTY
FIKKSTSLPP TTQLIVQRFV PLPAVSLASS LNVICMRWNE LRTGIEVYEK GGKVVGVSKT
AAKQAVTDTT LVRAFLPVPL LLAPPCIMPF LERYKWVSGS PWRHLFVNAI VCTLSFAASL
PVALALFPQE STIATSVLEP EIQSKTNSEQ LFYNKGL
//
