ID A0A016TF12_9BILA Unreviewed; 529 AA.
AC A0A016TF12;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Sulfatase N-terminal domain-containing protein {ECO:0000259|Pfam:PF00884};
GN Name=Acey_s0106.g3741 {ECO:0000313|EMBL:EYC01524.1};
GN ORFNames=Y032_0106g3741 {ECO:0000313|EMBL:EYC01524.1};
OS Ancylostoma ceylanicum.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC Ancylostomatinae; Ancylostoma.
OX NCBI_TaxID=53326 {ECO:0000313|EMBL:EYC01524.1, ECO:0000313|Proteomes:UP000024635};
RN [1] {ECO:0000313|Proteomes:UP000024635}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=HY135 {ECO:0000313|Proteomes:UP000024635};
RX PubMed=25730766; DOI=10.1038/ng.3237;
RA Schwarz E.M., Hu Y., Antoshechkin I., Miller M.M., Sternberg P.W.,
RA Aroian R.V.;
RT "The genome and transcriptome of the zoonotic hookworm Ancylostoma
RT ceylanicum identify infection-specific gene families.";
RL Nat. Genet. 47:416-422(2015).
CC -!- COFACTOR:
CC Name=Ca(2+); Xref=ChEBI:CHEBI:29108;
CC Evidence={ECO:0000256|ARBA:ARBA00001913};
CC -!- SIMILARITY: Belongs to the sulfatase family.
CC {ECO:0000256|ARBA:ARBA00008779}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EYC01524.1}.
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DR EMBL; JARK01001442; EYC01524.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A016TF12; -.
DR Proteomes; UP000024635; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.30.1120.10; -; 1.
DR Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 1.
DR InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR InterPro; IPR024607; Sulfatase_CS.
DR InterPro; IPR000917; Sulfatase_N.
DR PANTHER; PTHR42693:SF15; ARYLSULFATASE; 1.
DR PANTHER; PTHR42693; ARYLSULFATASE FAMILY MEMBER; 1.
DR Pfam; PF00884; Sulfatase; 1.
DR Pfam; PF14707; Sulfatase_C; 1.
DR SUPFAM; SSF53649; Alkaline phosphatase-like; 1.
DR PROSITE; PS00523; SULFATASE_1; 1.
DR PROSITE; PS00149; SULFATASE_2; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000024635};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..15
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 16..529
FT /note="Sulfatase N-terminal domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5012294268"
FT DOMAIN 25..347
FT /note="Sulfatase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00884"
SQ SEQUENCE 529 AA; 59277 MW; DD05B43FC595B06B CRC64;
MKRLLLCALM GIVHSCERPP SPSHPNIVLL VVDDMGFGDV ASYGHPTQEY TSIDRMAHEG
TRFTQAYSAD SLCSPSRSGF MTGRLPIRLG TVGGKRIFQP YDVGGLPKNE TTMAEMLKQA
GYVTGMVGKW HLGINAHNRT DGSHLPSKRG FDFVGLNLPF TNAWECDTTG EYYKNGPDPS
RCFLYDGDEI VQQPIRFQWM TENLVHDWRR FLQERLQKDQ KKTPFFFYFS FPQVHSTQFA
NPSFLGSSVR GMYGDSINEM SWAIGEVLDS LLKAGIAENT LVIFMSDHGP HAELCLNGGS
TAGLKGGKSN SYEGGFRIPF IAWQPGTVKA GRVSHEVISS MDLYRTFRDM QNCPQQRGDL
PTRNQHSVEA TTVFGWNKHT GGTIHYKTSP IFLNDTVDPN LSYFCPNGKP RADWYVSASC
PDEHLTTHDP PSVFDLAKDP YERYALEESD FVKQMRSQGA NIVKEHRQTL VPVPIQMGHF
DKNVVPCCDP PACRCDKITR REKANEEPSL HYPSVYKFFE GIGGIKGGI
//
