ID A0A016TMA9_9BILA Unreviewed; 336 AA.
AC A0A016TMA9;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=K+ channel tetramerisation domain protein {ECO:0008006|Google:ProtNLM};
GN Name=Acey_s0089.g2211 {ECO:0000313|EMBL:EYC04094.1};
GN Synonyms=Acey-kvs-3 {ECO:0000313|EMBL:EYC04094.1};
GN ORFNames=Y032_0089g2211 {ECO:0000313|EMBL:EYC04094.1};
OS Ancylostoma ceylanicum.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC Ancylostomatinae; Ancylostoma.
OX NCBI_TaxID=53326 {ECO:0000313|EMBL:EYC04094.1, ECO:0000313|Proteomes:UP000024635};
RN [1] {ECO:0000313|Proteomes:UP000024635}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=HY135 {ECO:0000313|Proteomes:UP000024635};
RX PubMed=25730766; DOI=10.1038/ng.3237;
RA Schwarz E.M., Hu Y., Antoshechkin I., Miller M.M., Sternberg P.W.,
RA Aroian R.V.;
RT "The genome and transcriptome of the zoonotic hookworm Ancylostoma
RT ceylanicum identify infection-specific gene families.";
RL Nat. Genet. 47:416-422(2015).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EYC04094.1}.
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DR EMBL; JARK01001425; EYC04094.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A016TMA9; -.
DR STRING; 53326.A0A016TMA9; -.
DR Proteomes; UP000024635; Unassembled WGS sequence.
DR GO; GO:0008076; C:voltage-gated potassium channel complex; IEA:InterPro.
DR GO; GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro.
DR GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR CDD; cd18317; BTB_POZ_Kv; 1.
DR Gene3D; 1.20.120.350; Voltage-gated potassium channels. Chain C; 1.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR003971; K_chnl_volt-dep_Kv9.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR InterPro; IPR003131; T1-type_BTB.
DR InterPro; IPR027359; Volt_channel_dom_sf.
DR PANTHER; PTHR11537:SF286; POTASSIUM VOLTAGE-GATED CHANNEL PROTEIN SHAB; 1.
DR PANTHER; PTHR11537; VOLTAGE-GATED POTASSIUM CHANNEL; 1.
DR Pfam; PF02214; BTB_2; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR PRINTS; PR00169; KCHANNEL.
DR PRINTS; PR01494; KV9CHANNEL.
DR SUPFAM; SSF54695; POZ domain; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE 4: Predicted;
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Potassium {ECO:0000256|ARBA:ARBA00022958};
KW Potassium channel {ECO:0000256|ARBA:ARBA00022826};
KW Potassium transport {ECO:0000256|ARBA:ARBA00022538};
KW Reference proteome {ECO:0000313|Proteomes:UP000024635};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 173..195
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 207..229
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 19..118
FT /note="Potassium channel tetramerisation-type BTB"
FT /evidence="ECO:0000259|Pfam:PF02214"
FT DOMAIN 174..316
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
SQ SEQUENCE 336 AA; 38338 MW; 5153D437C5805589 CRC64;
MTETCALLQA NGSVPSPTVV INVGGRRARL SVDMVSRRLE NCRLSVFCRK SHIEKLTDCD
AYFEQSGEYY FERSPIIFEY IVDFFVTGKL HRPMDICPIR LRYELDYWRI PVHFLSPCCM
LEENNNLNKK RIEMAAQESS CPASSFDKVW MGPMRLSLYR LLENPRSSSG AKALSIISAF
FVLLSLLGLI LSSMPELQDQ NKEPHQALQW LELCCMAYFT VEYLARFFVN PNKAKFVRSP
LNVIDVLTIL PFIIEAFNEL QWIKNFRGAM LVVRVMRLAR VARIFKLARY STGLRAFGET
MKKSAAELSM LGMFLVTDIA GNMVSDVIAG RVDSSD
//
