ID   A0A016TN94_9BILA        Unreviewed;       361 AA.
AC   A0A016TN94;
DT   11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT   11-JUN-2014, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EYC04225.1};
GN   Name=Acey_s0089.g2294 {ECO:0000313|EMBL:EYC04225.1};
GN   ORFNames=Y032_0089g2294 {ECO:0000313|EMBL:EYC04225.1};
OS   Ancylostoma ceylanicum.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC   Ancylostomatinae; Ancylostoma.
OX   NCBI_TaxID=53326 {ECO:0000313|EMBL:EYC04225.1, ECO:0000313|Proteomes:UP000024635};
RN   [1] {ECO:0000313|Proteomes:UP000024635}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=HY135 {ECO:0000313|Proteomes:UP000024635};
RX   PubMed=25730766; DOI=10.1038/ng.3237;
RA   Schwarz E.M., Hu Y., Antoshechkin I., Miller M.M., Sternberg P.W.,
RA   Aroian R.V.;
RT   "The genome and transcriptome of the zoonotic hookworm Ancylostoma
RT   ceylanicum identify infection-specific gene families.";
RL   Nat. Genet. 47:416-422(2015).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EYC04225.1}.
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DR   EMBL; JARK01001425; EYC04225.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A016TN94; -.
DR   STRING; 53326.A0A016TN94; -.
DR   Proteomes; UP000024635; Unassembled WGS sequence.
DR   CDD; cd02440; AdoMet_MTases; 1.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR025714; Methyltranfer_dom.
DR   InterPro; IPR048711; Rv2258c-like_HTH.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR45581:SF3; METHYLTRANFER_DOM DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR45581; PROTEIN CBG10435; 1.
DR   Pfam; PF21320; HTH_65; 1.
DR   Pfam; PF13847; Methyltransf_31; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000024635}.
FT   DOMAIN          20..88
FT                   /note="S-adenosylmethionine-dependent methyltransferase
FT                   Rv2258c-like winged HTH"
FT                   /evidence="ECO:0000259|Pfam:PF21320"
FT   DOMAIN          170..337
FT                   /note="Methyltransferase"
FT                   /evidence="ECO:0000259|Pfam:PF13847"
SQ   SEQUENCE   361 AA;  39963 MW;  7F110FA2BAD73B6A CRC64;
     MVEKSDFQKR LMQIGIDGIL SASIAMGNRL QLFQALAKVG SEDKPATPAE VATESGCKER
     YVKEWLSVMA TADLITVTED EKFYIKKEHV EDLAGDVNIS IDSFLPICMK VYDQLCQVFK
     KEGPFGLNYS EYTDFYVAMA DFSEAMHRKH LISDLIPALG GNVKERLEQG GMMCLDVGCG
     KGFQAALLAQ NFPKSNFTGI DVTLEAVHLA NQQRKDNGET YENLAIIQMD GAKMDADWTN
     KFDLVTIFDA CHDQMRPDLC LKEIHRVLKP GGVFGMVEIM GYSNVFKDKQ ALGSTAAMMY
     GISTFVCLPV GSNSEDALCL GAMWGKERAL KMLKEAGFAD ARLVETPYYG ANTTLYVCTK
     N
//