UniProt: A0A016U4G3

Database: UniProt
Entry: A0A016U4G3_9BILA

LinkDB:  A0A016U4G3_9BILA 
Original site:  A0A016U4G3_9BILA

All links

Ontology (2)   
   GO (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
DNA sequence (1)   
   EMBL (1)   
Protein domain (11)   
   InterPro (7)   
   Pfam (3)   
   PROSITE (1)   
Literature (1)   
   PubMed (1)   
All databases (16)   

Download RDF

ID   A0A016U4G3_9BILA        Unreviewed;      2281 AA.
AC   A0A016U4G3;
DT   11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT   11-JUN-2014, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   RecName: Full=chitin synthase {ECO:0000256|ARBA:ARBA00012543};
DE            EC=2.4.1.16 {ECO:0000256|ARBA:ARBA00012543};
GN   Name=Acey_s0059.g3014 {ECO:0000313|EMBL:EYC09727.1};
GN   ORFNames=Y032_0059g3014 {ECO:0000313|EMBL:EYC09727.1};
OS   Ancylostoma ceylanicum.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC   Ancylostomatinae; Ancylostoma.
OX   NCBI_TaxID=53326 {ECO:0000313|EMBL:EYC09727.1, ECO:0000313|Proteomes:UP000024635};
RN   [1] {ECO:0000313|Proteomes:UP000024635}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=HY135 {ECO:0000313|Proteomes:UP000024635};
RX   PubMed=25730766; DOI=10.1038/ng.3237;
RA   Schwarz E.M., Hu Y., Antoshechkin I., Miller M.M., Sternberg P.W.,
RA   Aroian R.V.;
RT   "The genome and transcriptome of the zoonotic hookworm Ancylostoma
RT   ceylanicum identify infection-specific gene families.";
RL   Nat. Genet. 47:416-422(2015).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=[(1->4)-N-acetyl-beta-D-glucosaminyl](n) + UDP-N-acetyl-alpha-
CC         D-glucosamine = [(1->4)-N-acetyl-beta-D-glucosaminyl](n+1) + H(+) +
CC         UDP; Xref=Rhea:RHEA:16637, Rhea:RHEA-COMP:9593, Rhea:RHEA-COMP:9595,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:17029, ChEBI:CHEBI:57705,
CC         ChEBI:CHEBI:58223; EC=2.4.1.16;
CC         Evidence={ECO:0000256|ARBA:ARBA00000319};
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EYC09727.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; JARK01001395; EYC09727.1; -; Genomic_DNA.
DR   Proteomes; UP000024635; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004100; F:chitin synthase activity; IEA:UniProtKB-EC.
DR   CDD; cd04190; Chitin_synth_C; 1.
DR   CDD; cd09076; L1-EN; 1.
DR   CDD; cd01650; RT_nLTR_like; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 3.60.10.10; Endonuclease/exonuclease/phosphatase; 1.
DR   InterPro; IPR004835; Chitin_synth.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR036691; Endo/exonu/phosph_ase_sf.
DR   InterPro; IPR005135; Endo/exonuclease/phosphatase.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR000477; RT_dom.
DR   PANTHER; PTHR22914; CHITIN SYNTHASE; 1.
DR   PANTHER; PTHR22914:SF12; CHITIN SYNTHASE CHS-1; 1.
DR   Pfam; PF03142; Chitin_synth_2; 1.
DR   Pfam; PF03372; Exo_endo_phos; 1.
DR   Pfam; PF00078; RVT_1; 1.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR   SUPFAM; SSF56219; DNase I-like; 1.
DR   SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
DR   PROSITE; PS50878; RT_POL; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000024635};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        40..65
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        131..152
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1160..1183
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1189..1208
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1240..1258
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1278..1297
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1309..1332
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1795..1820
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1832..1849
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1861..1883
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1889..1908
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1915..1938
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        2113..2131
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        2172..2193
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          726..993
FT                   /note="Reverse transcriptase"
FT                   /evidence="ECO:0000259|PROSITE:PS50878"
SQ   SEQUENCE   2281 AA;  260986 MW;  388390FB692AC595 CRC64;
     MMSSGDDDFR WNVFRSHKRA TTEKPSLTPW MITSLQATKL LLFLVCNTFL TLGAAISKIC
     ILILATNLWE KRYTSDPYAR RCTRVPVERT PRAVAAMYLS LMLIQSVPDV VSMMRSLMRL
     YRGDKAGRVR FSFVALETLR AFGLSLLVFT VFPQLDLYRC LCLCACFPII TALQHLMSTI
     SSTFKPGRSF GTRMSHFLPQ YPAHRALPSQ TSDGTATGER RSNLGLRRTS LISDQGDKGT
     TRHGDCFMLC TYNARTVSTN ADLHALLEAA GRIKFHVIAL QETKSKKSEV RQLNDGTLII
     RGEKFPSRNV GGVGFVVHPS VVHLVDSHEI LSPRLAILRL HLPRRKSISI INCYSPTLTA
     DESELDTFYE RLEDVIHNEK SFYKFVVGDF NAQLGKAEDD EYRIGRFGLG DRNENGNRLA
     GLLSAARLFH GNSVFMKKDH RRWTWESPNG TTHTEIDHIL TNRRWCLLDV SVVPSFCCGS
     DHRLLRAKIR FSCTIEKNVC HRGGGKRAVV YDGAVLEKAL SELDWHIMED PTEDYDLLLQ
     KLQACAERAS TPQTTNLERI SIATKELLER RRALRLDPNA SHIEQLVANA CCRRALQEDL
     QKHRRKKILE AAEGRRSLKK CRRDLRDHNI PLTALLNEEG IVTSSRREME AITERFYTNL
     FRSSVPVMNP NIPAGDEPPR ILPAEVRVAI QSMKPSTAPG PDRISADLLR AGGHHLHVIL
     AEHMSSYLRK ERIPNQWRTS RTVLIHKKGD REDLRNYRPI CLLSVLYKLF TKIILTRISR
     TLDEAQPQEQ AGFRQGFSCM DNIQTVSRVI EVCREYRLPL VLTFVDYEKA FDSVETNAIL
     SALVDQGVDA SYVRTLADCY RQCSTTVQLF QRPITIPIAK GVRQGDTISP KLFTAALQWA
     MKSLNWDERG IRVDGRFLSN LRFADDIVLF SRSTEEAQAM LNELNEVGKK IGLRMNRTKT
     KFMKNAFCDG ERIELEGTQI AETMSYVYLG RSLNMENDLK EELGRRRRAA WAAFGPLREA
     TDQLTDHELR AHLFDSTVLP ALCYAAETWS DTAATLKSLR TVHRALERCL LRYNRRTQLQ
     AGLRSSDLRR ISRLHDPAEY ISKAKHRWAG HIMRREDDRW TRRTLEWIPR ETKRPRGRPP
     TRWADVFAAR MDQLNAQLET ILSTTTLPHL ILFLGLFSAT YLWNVMETPF QGVWVLPLGL
     FSISIGFWES WVGKRHSGTI FHELYQVKYG LRKLNVSTRL VIAVVRIVVV VTIMSYAAQG
     RVKPYLFLNV LTSYSFRFKQ TQLLLAAFGI IFLNLSLRGC ARFLAAIGMK AFSILHPVTI
     VPAVGYAIVA FICNQRICGI AGSLAKLGLR WCCDQWGRNT RPFDDWYICM IWLAVGAYRG
     YQFVHQKSYD RCDEVVDSMP PVPNGFCIEQ SLVVFHNSLS KAEPTLDIDD DHGDPLDELR
     VRNDEVDKTL TLYMCATMWH ETATEMAQML RSILKLDEEH AHRLSTKKVD QLRFRLEGHI
     FFDDAWEDQT EFGITKRVPN DFFHTFFDTL SELTGELVDE SGLMMSRILV NTPYGGRLVV
     RLPAGTLLFV HLKDKKLIRH KKRWSQVMYM YYLLGHRIMD SPLSIEDRQQ MADNTFILAI
     DGDSKFEPEA VMRLLNLMNT KSDIGCACGR IHPIGSGVMV WYQKFEYAIA HWFQKAAEHV
     FGCVLCAPGC FSLFRASALM DDNIMHKYTK TAQEPRHFVQ YDQGEDRWLS TLMLKQGYRI
     EYVAASDAET YAPEGFEEFF NQRRRWTPSS IANTIDLLAD YKRASENNDS ISMSYIAYQF
     IVIFFSMLGP AIMFCMLVFA QVAAFGVDSA KMMVYNGVPI SLFIVLCFTT ESNVQLFYAK
     LMSIIYAFVM LAVLIATASQ IVLETVISPT SMFIVTMVLV FFIAACLHPK EFTNIIYGIV
     FFLMIPSTYV FLTLYSLINL NVINWGTREA VAKATGKVET SSTFERWLRR IGEGPWSALC
     PSLRARPDEA MQLIERRLER MERSLTNLQK ISEDDEIAVE KLKKVAKDVD EAEGTNEVVE
     IRRPVVEPEP MRVVDKYMWM EGDYLRVCER GRLKAAEEQF WRQLIEAYLK PIESTPQQQS
     AIAEGLASLR NNIAFAIILV NALLALAIYL IQKHKNVLSI RWTPYRDFKW TKMNEMTGQF
     EETKDPLKID PLGMAIIVFL LGILVVQTIG MLIHRLNTMI GAFQEVNQLH DLVPALKFNK
     IDDERILTAA RQMIDTTSYA MSHAADGYTR HRELDADNDN VLYKLQRARL AKRMQRAEEK
     K
//

DBGET integrated database retrieval system